Protein Alignment CG9541 and AK8

DIOPT Version :10

• Sequence 1: NP_001260273.1
• Gene: CG9541 / 34220
• FlyBaseID: FBgn0032083
• Length: 646
• Species: Drosophila melanogaster
• Sequence 2: XP_005272226.1
• Gene: AK8 / 158067
• HGNCID: 26526
• Length: 491
• Species: Homo sapiens
• Alignment Length: 548
• Identity: 107/548 - (19%)
• Similarity: 175/548 - (31%)
• Gaps: 196/548 - (35%)

  Fly    64 DPPKVPVIFVLGGPGSGKVTHCDTFMQERRGVTHINMMDLLQQYAMGNDMQDFSQLSSKTVTEV- 127
            |...||.|.:||.|.|||.|......:      |:|...|..:..:.|:.       |.|.||.
Human    65 DNDNVPRIVILGPPASGKTTIAMWLCK------HLNSSLLTLENLILNEF-------SYTATEAR 116

  Fly   128 -LMLEMKMAPAA-----------------KAYLISGYPRSMRDVVEYSEKIQVV----NGVILIS 170
             |.|:.|..|:|                 :.:::.|.|.:.    |.:.:||.:    ..||::|
Human   117 RLYLQRKTVPSALLVQLIQERLAEEDCIKQGWILDGIPETR----EQALRIQTLGITPRHVIVLS 177

  Fly   171 WRQSVLQKQIDYGAKLGHVVLSLAKMELENFFKNVMPVAD--YFDQSDMLLAVNGERAPTEVYKD 233
            ...:||.::                    |..|.:.|...  |....|.         |.|....
Human   178 APDTVLIER--------------------NLGKRIDPQTGEIYHTTFDW---------PPESEIQ 213

  Fly   234 FRTAVLDILSTLENQEAVMNGVTGMGRGIHDIPGSIVSVDTAPSQA----QQGTQIAEDNDVTNA 294
            .|..|.:.:|.||..:.::.....:.|.|...| .|:.|.:|....    .|.....:.|..|||
Human   214 NRLMVPEDISELETAQKLLEYHRNIVRVIPSYP-KILKVISADQPCVDVFYQALTYVQSNHRTNA 277

  Fly   295 SETAGTVLARDLAIERMDGGPNGAVTALKTGTTSADDDSGVVVTQQPKLRQAAGPDESGSDLPPI 359
            ..|                                                            |.
Human   278 PFT------------------------------------------------------------PR 282

  Fly   360 IWVIGGPGSNKATLCLKAVGLNPGWAHISV--GRLLRNITDSAPRAN----TESFAVKEALAAGD 418
            :.::|..||.|:   |:|..|...:..::|  |:||:...  |.|..    .:.|..|| :|..|
Human   283 VLLLGPVGSGKS---LQAALLAQKYRLVNVCCGQLLKEAV--ADRTTFGELIQPFFEKE-MAVPD 341

  Fly   419 MAPEKSLNQLLETNLRQLRDRTGIIVDGYPRNLQQVK------------YFEN------------ 459
            ....|.|:|.|:   :|...:.|.::.|.||:|.|..            :|.|
Human   342 SLLMKVLSQRLD---QQDCIQKGWVLHGVPRDLDQAHLLNRLGYNPNRVFFLNVPFDSIMERLTL 403

  Fly   460 -------------KYKQRPPIILLDCSKLQLGRGRIDDTVSSFRRRLELFREQTLPMLKILDTSN 511
                         .||. ||.:.:....||..:    |.....:.:::||...:..:.::..::.
Human   404 RRIDPVTGERYHLMYKP-PPTMEIQARLLQNPK----DAEEQVKLKMDLFYRNSADLEQLYGSAI 463

  Fly   512 RLQIVDGDTDSPSVQREFERLIRNHIQR 539
            .|   :||.|..:|....|..|.|.:.:
Human   464 TL---NGDQDPYTVFEYIESGIINPLPK 488

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG9541	NP_001260273.1	ADK	70..230	CDD:238713	37/184 (20%)
		aden_kin_iso1	358..521	CDD:130427	44/205 (21%)
AK8	XP_005272226.1	DD_AK8	9..65	CDD:438548	107/548 (20%)
		ADK	71..261	CDD:238713	49/236 (21%)
		ADK	282..474	CDD:238713	44/208 (21%)