DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG9541 and ak5

DIOPT Version :9

Sequence 1:	NP_001260273.1	Gene:	CG9541 / 34220	FlyBaseID:	FBgn0032083	Length:	646	Species:	Drosophila melanogaster
Sequence 2:	XP_012815974.2	Gene:	ak5 / 100127649	XenbaseID:	XB-GENE-5764752	Length:	560	Species:	Xenopus tropicalis

Alignment Length:	501	Identity:	118/501 - (23%)
Similarity:	207/501 - (41%)	Gaps:	115/501 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    63 FDP--PKVPVIFVLGGPGSGKVTHCDTFMQERRGVTHINMMDLLQQYAMGNDMQDFSQLSSKTVT 125
            |||  |...:|.|:|||||||.|. ...:.||.|..:|::.:||::............|.:|.:|
Frog   125 FDPSRPHPKIILVIGGPGSGKGTQ-SLKIAERYGFEYISVGELLRKKIHSTSSNRKWSLIAKIIT 188

  Fly   126 -------EVLMLEMK----MAPAAKAYLISGYPRSMRDVVEYSEKIQVVNGVILISWRQSVLQKQ 179
                   |..:.|:|    ..|.::..:|.|:||.:...:.:.::|...:.|:.::.....|:::
Frog   189 TGELAPQETTITEIKQKLMQIPDSEGIVIDGFPRDVAQALSFEDQICTPDLVVFLACASHKLKER 253

  Fly   180 IDYGA-KLGHV--VLSLAKMELENFFKNVMPVADYFDQSDMLLAVNGERAPTEVYKDFRTAVLDI 241
            :...| :.|..  .|...:..|.||.:|.:|:.:||.:..:::..:.:|...||:.|...||
Frog   254 LQKRAEQQGRPDDNLKAIQRRLMNFKQNAVPLVNYFQEKGLIITFDADREEEEVFCDISAAV--- 315

  Fly   242 LSTLENQEAVMNGVTGMGRGIHDIPGSIVSVDTAPSQAQQGTQIAEDND-----VTNASETAGTV 301
                :|:                         ..|::    |.:||.::     :.::.:|.
Frog   316 ----DNK-------------------------LFPAK----TPVAEPSELDLSLIIDSGDTC--- 344

  Fly   302 LARDLAIERMDGGPNGAVTALKTGTTSADDDSGVVVTQQPKLRQAAGPD---ESGSDLPPIIWVI 363
               ||.:...|                          |:.:|.|..|.|   ........:|:|:
Frog   345 ---DLELNFED--------------------------QRHELMQPFGDDCRLREELKKAKVIFVL 380

  Fly   364 GGPGSNKATLCLKAV---GLNPGWAHISVGRLLRNITDSAPRANTE-SFAVKEALAAGDMAPEKS 424
            |||||.|.|.|.|..   ||:|    ::|..||:  :|.|  ..|| |..:|:.:..||..|...
Frog   381 GGPGSGKGTQCEKLAHRYGLSP----LAVSELLQ--SDLA--TFTERSKLIKDIMEHGDQVPMDI 437

  Fly   425 LNQLL-ETNLRQLRDRTGIIVDGYPRNLQQVKYFENKYKQRPPIILLDCS---------KLQLGR 479
            :.::: ||....|.:..|.:.||:||..:|.:.||.|..:...::.||||         |.....
Frog   438 ILEIVKETMSSCLGNSKGFLFDGFPRETKQAEEFECKISKPNIVLYLDCSAETMTSRLQKRSKAS 502

  Fly   480 GRIDDTVSSFRRRLELFREQTLPMLKILDTSNRLQIVDGDTDSPSV 525
            .|.|....:.|||||.:.:...|::...|..:.|..::.:.....|
Frog   503 HRNDINTETIRRRLEAYYQAINPIITYYDRKSLLYKINAEKSPEDV 548

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9541	NP_001260273.1	aden_kin_iso1	67..238	CDD:130427	44/184 (24%)
		ADK	70..230	CDD:238713	41/173 (24%)
		aden_kin_iso1	358..521	CDD:130427	53/176 (30%)
		ADK	359..521	CDD:238713	53/175 (30%)
ak5	XP_012815974.2	ADK	134..307	CDD:238713	41/173 (24%)
ak5	XP_012815974.2	aden_kin_iso1	372..559	CDD:130427	54/185 (29%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1378291at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X3899
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	3.010