DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG9541 and ak5

DIOPT Version :9

Sequence 1:	NP_001260273.1	Gene:	CG9541 / 34220	FlyBaseID:	FBgn0032083	Length:	646	Species:	Drosophila melanogaster
Sequence 2:	NP_001093554.1	Gene:	ak5 / 100003595	ZFINID:	ZDB-GENE-030131-8256	Length:	563	Species:	Danio rerio

Alignment Length:	493	Identity:	112/493 - (22%)
Similarity:	201/493 - (40%)	Gaps:	132/493 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly    63 FDP--PKVPVIFVLGGPGSGKVTHCDTFMQERRGVTHINMMDLLQQYAMGN--DMQDFSQLS--- 120
            |||  |:..||.::|||||||.|.| ..:.||.|..::::.:||::..:.|  ..:.:|.::
Zfish   125 FDPSRPRPKVILIIGGPGSGKGTQC-LKIAERYGFEYVSVGELLRKKMIHNATSNRKWSLIARII 188

  Fly   121 --------SKTVTEVLMLEMKMAPAAKAYLISGYPRSMRDVVEYSEKIQVVNGVILISWRQSVLQ 177
                    ..|:||:....||: |.|...:|.|:||.:...:.:.:::...:.|:.::.....|:
Zfish   189 TNGELAPQETTITEIKQKIMKI-PEASGIVIDGFPRDVGQALSFEDQVCTPDLVVFLACSNQRLK 252

  Fly   178 KQIDYGAKLGHVVLSLAK---MELENFFKNVMPVADYFDQSDMLLAVNGERAPTEVYKDFRTAVL 239
            ::::..|:.........|   ..|.||.:|.:|:..||.:..:::.::.:|...||:       .
Zfish   253 ERLEKRAEQQGRPDDNPKAIDRRLTNFKQNAIPLVKYFQEKGLIVTLDADRDEEEVF-------Y 310

  Fly   240 DILSTLEN-----QEAVMNGVTGMGRGIHDIPGSIVSVDTAPSQAQQGTQIAEDNDVTNASETAG 299
            ||..|::|     :|.|        .|..::..|:::..::.:..........|.:|...:|..|
Zfish   311 DISMTVDNKLFPTKEPV--------AGPSELDLSLIADSSSLTDVPAKFDEQADEEVAEYAEAIG 367

  Fly   300 TVLARDLAIERMDGGPNGAVTALKTGTTSADDDSGVVVTQQPKLRQAAGPDESGSDLPPIIWVIG 364
                                            :|..:.|::.|                :|:|||
Zfish   368 --------------------------------ESFPMETKKSK----------------VIFVIG 384

  Fly   365 GPGSNKA-------------TLCLKAVGLNPGWAHISVGRLLRNITDSAPRANTESFAVKEALAA 416
            ||||.||             .||...:..:...:|...||.||::                 |..
Zfish   385 GPGSGKALQSEKIEERYSLKRLCPGDILCSELQSHSERGRFLRDL-----------------LER 432

  Fly   417 GDMAPEKSLNQLL-ETNLRQLRDRTGIIVDGYPRNLQQVKYFENKYKQRPPIILLDCSKLQLGRG 480
            |:..||.:|..|| |.....:|...|.:|.|:|:|.:|.:.:|.|..|...::||:||.
Zfish   433 GEQLPEDTLLDLLCEAMASTVRQGKGFLVTGFPKNEKQAQEYEAKMGQPDIVLLLECSA------ 491

  Fly   481 RIDDTVSSFRRRLELFREQTLPMLKILDTSNRLQIVDG 518
               |.:|   |||:.....:|...:..|...|.: |||
Zfish   492 ---DIMS---RRLQQRATCSLHSKEARDRDTRRR-VDG 522

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9541	NP_001260273.1	aden_kin_iso1	67..238	CDD:130427	43/186 (23%)
		ADK	70..230	CDD:238713	41/175 (23%)
		aden_kin_iso1	358..521	CDD:130427	50/175 (29%)
		ADK	359..521	CDD:238713	50/174 (29%)
ak5	NP_001093554.1	aden_kin_iso1	133..317	CDD:130427	46/192 (24%)
		ADK	134..308	CDD:238713	41/175 (23%)
		aden_kin_iso1	375..562	CDD:130427	51/194 (26%)
		ADK	379..552	CDD:238713	50/174 (29%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170582286
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0563
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG58863
OrthoDB	1	1.010	-	-		D1378291at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR23359
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X3899
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	10	9.820