DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG32984 and CG15695

DIOPT Version :9

Sequence 1:	NP_788014.2	Gene:	CG32984 / 34218	FlyBaseID:	FBgn0052984	Length:	650	Species:	Drosophila melanogaster
Sequence 2:	NP_650920.3	Gene:	CG15695 / 42468	FlyBaseID:	FBgn0038832	Length:	725	Species:	Drosophila melanogaster

Alignment Length:	602	Identity:	218/602 - (36%)
Similarity:	333/602 - (55%)	Gaps:	36/602 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly    47 NQKRFYVNSSNCQMAYVEPFNAEFTKLYTPKNFTRCSNQSDLVTVHFDSILKQYVLHVDEEVLHK 111
            |.|:::|:|..|||::..||......:|...::..|....|::||:::.....|.||.:|
  Fly   152 NGKKYFVHSPQCQMSHPNPFANNIQHIYKKHSYIVCDKSRDMITVNYNVTDSTYRLHKNE----- 211

  Fly   112 LSQSKSNKFACFYQNITYGQS--ADHYDRMGKKTKFTHDYVVPLNVQGMLVECRSGDEKRILQED 174
                  |...||.|.:..|.|  |||..::|...:|..|::||..|..|:..||.....::.|:|
  Fly   212 ------NSTCCFKQILRAGTSANADHKYKLGPCVEFHQDFLVPTEVSAMITYCRRPPFDKVSQKD 270

  Fly   175 AFSFVQYQK---TSPNLDIDRKASVIMYGIDTVSRTNLRRLMPVVFGFLKSPGWYEMMGYNKVAD 236
            |||||..:|   .:|.....|:.||:::|||::||.||...||.::.:|.:..|:|:.||||:.|
  Fly   271 AFSFVHPRKDQIENPTTPHRRRPSVLLWGIDSISRMNLELTMPRMYEYLNNQHWFELQGYNKMGD 335

  Fly   237 NTYPNIFSILTGYSPNSAKNQICDTTQPGCLDKIPFIWKDMKKNGYLTAYAEDTVFSNIFNYMKP 301
            ||:||:.::|||::...| |..|...:...||..||||||.|..||.||:|||....:.|:|...
  Fly   336 NTFPNLMAVLTGFNKTYA-NARCHPEKVRGLDACPFIWKDFKDKGYTTAFAEDWSKFSTFDYSSR 399

  Fly   302 GFLSRPTDYYFRPLLDALEKETIKLYCPGCKMVYCLGRRLANSYIFDYCRQF--MQRYVADRPIW 364
            ||.:.|||.|.|||:.|:||| :.:...| :|.|||||:.|:.||:|...||  :.|   :...:
  Fly   400 GFFNPPTDVYGRPLVLAVEKE-LTILQRG-QMPYCLGRKPASEYIYDMGVQFTMVNR---NSTFF 459

  Fly   365 GFFWSNHISHDDFSMLSAMQHKIVGDLLNFEKDGSFEHTIMIFFSDHGSRFGPLMRTRESFLEER 429
            |.||:|..||:||||.|||..::|..:...:|:|..::||:|||||||||||||......|:|||
  Fly   460 GMFWTNTFSHNDFSMPSAMDERMVKYMRTLDKNGIMDNTIIIFFSDHGSRFGPLRNLDSGFVEER 524

  Fly   430 QPIMFIYLPPWFREKYPRYVEALAQNQNRLSSNFDIYNTLKHIINIEGLVEDTKWSYDCPQCQSL 494
            .|.::|.:|.|.|||||:.:..|..|:|||:|.:||:.||:||:.::...:.......|..|.|:
  Fly   525 LPFIYIRVPRWIREKYPKLLRNLQMNKNRLTSPYDIHATLRHILELDTPKDKLPRPDGCSSCHSV 589

  Fly   495 FYELPESRSCSEAAIPEAYCTCHNYEEV-QEDHGTWRMAELVVDRINQFLQYHNLQNLCSSLTLK 558
            |.|:..||:||:|.|.:.:|.|:::.:| ..|.....|:..:|:.||:::........||.|.|.
  Fly   590 FEEVDWSRNCSQAGIEDHWCACNSFSDVPTTDPSARSMSTQLVEAINEYVASKKGTKRCSRLKLN 654

  Fly   559 LVNITEVRITESDEHVSLGKGLRHYHTKFQVHQNLAEFFATVLYDRKTEELQINVELISRINIYR 623
            .::..:.|          |...| |..:.......|.|.|||.:|...:.:...:..|||::.|.
  Fly   655 RISSVQRR----------GNSNR-YLIQLMAQPGDALFEATVDWDASAQRIPAQMPSISRLDTYA 708

  Fly   624 PDASCLDDNIQKLFCIC 640
            ..:.|......|.:|||
  Fly   709 AKSRCSSVKETKKYCIC 725

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG32984	NP_788014.2	DUF229	75..561	CDD:308570	189/493 (38%)
CG15695	NP_650920.3	DUF229	180..656	CDD:281053	189/492 (38%)
CG15695	NP_650920.3	ALP_like	293..571	CDD:293745	130/283 (46%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45469430
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG27040
OrthoDB	1	1.010	-	-		D31599at6960
OrthoFinder	1	1.000	-	-		FOG0005924
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR10974
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	6	5.960