DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG9525 and CG15695

DIOPT Version :9

Sequence 1:	NP_609260.1	Gene:	CG9525 / 34217	FlyBaseID:	FBgn0032080	Length:	678	Species:	Drosophila melanogaster
Sequence 2:	NP_650920.3	Gene:	CG15695 / 42468	FlyBaseID:	FBgn0038832	Length:	725	Species:	Drosophila melanogaster

Alignment Length:	626	Identity:	177/626 - (28%)
Similarity:	285/626 - (45%)	Gaps:	87/626 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    35 EHYIKTSECHIPYINKPLENEKGNIKKQHT--ICSKDESLINLRFDEKSHQYLLYVNDHVAQLKL 97
            ::::.:.:|.:.:.| |..|...:|.|:|:  :|.|...:|.:.::.....|.|:.|::
  Fly   155 KYFVHSPQCQMSHPN-PFANNIQHIYKKHSYIVCDKSRDMITVNYNVTDSTYRLHKNEN------ 212

  Fly    98 RSMKKKSPNLIGYNCSYRELKR----LNRDYIVDAPVVYVCYLTDRSLKFEDQFLYSLGEEVKFW 158
                        ..|.::::.|    .|.|:                       .|.||..|:|.
  Fly   213 ------------STCCFKQILRAGTSANADH-----------------------KYKLGPCVEFH 242

  Fly   159 NGYIVPPSVEGMRATCRNELAEDL-QSDTFVLVQPPKTYA--PLISWHRIPNVLLIGFDGISQIN 220
            ..::||..|..|...||....:.: |.|.|..|.|.|...  |.....|.|:|||.|.|.||::|
  Fly   243 QDFLVPTEVSAMITYCRRPPFDKVSQKDAFSFVHPRKDQIENPTTPHRRRPSVLLWGIDSISRMN 307

  Fly   221 FRRNFPLVFNQLKMQDWFRMDGYTGIGENTQSNLMASLTGYSPHTLMNLKCDSSVIGCLKTVPLI 285
            .....|.::..|..|.||.:.||..:|:||..||||.|||:: .|..|.:|....:..|...|.|
  Fly   308 LELTMPRMYEYLNNQHWFELQGYNKMGDNTFPNLMAVLTGFN-KTYANARCHPEKVRGLDACPFI 371

  Fly   286 WKHFKKKGFITAYGEGIS--NLFDSEKYGIFEGTIDFYAR--------------HKNLQSCIDRR 334
            ||.||.||:.||:.|..|  :.||....|.|....|.|.|              ...:..|:.|:
  Fly   372 WKDFKDKGYTTAFAEDWSKFSTFDYSSRGFFNPPTDVYGRPLVLAVEKELTILQRGQMPYCLGRK 436

  Fly   335 FNIKHNYDYCEEFLKRHANTNRPFFGVFFGNGITNRSYDNARIQTELLDK-VKKFKKMGILTQSI 398
            ...::.||...:|..  .|.|..|||:|:.|..::..:.......|.:.| ::...|.||:..:|
  Fly   437 PASEYIYDMGVQFTM--VNRNSTFFGMFWTNTFSHNDFSMPSAMDERMVKYMRTLDKNGIMDNTI 499

  Fly   399 VVLFSYPVS---SVKEKKTNFSQEDLPILYIWLPPWFKAFRPEIVQALRINSKRLTSPYDLHLTL 460
            ::.||...|   .::...:.|.:|.||.:||.:|.|.:...|::::.|::|..|||||||:|.||
  Fly   500 IIFFSDHGSRFGPLRNLDSGFVEERLPFIYIRVPRWIREKYPKLLRNLQMNKNRLTSPYDIHATL 564

  Fly   461 QHLLELGERWPRAVDKLV---DCPTCQTLFAPVPENRTCSDAGIGESQCPCDSYKLLSSNQMKQL 522
            :|:|||..  |:  |||.   .|.:|.::|..|..:|.||.|||.:..|.|:|:..:.:......
  Fly   565 RHILELDT--PK--DKLPRPDGCSSCHSVFEEVDWSRNCSQAGIEDHWCACNSFSDVPTTDPSAR 625

  Fly   523 SVGKQIVRSINEFLNHHNLHELCHNLTLKSVKMVLQRKDRKLSSGSTYRAYFSANPNNAEFSTTI 587
            |:..|:|.:|||::......:.|..|.|..:..|.:|     .:.:.|.....|.|.:|.|..|:
  Fly   626 SMSTQLVEAINEYVASKKGTKRCSRLKLNRISSVQRR-----GNSNRYLIQLMAQPGDALFEATV 685

  Fly   588 RYANNRQELEYINVESINRLNNYQNDSSCMRRLRGRKFCIC 628
            .:..:.|.:. ..:.||:||:.|...|.|......:|:|||
  Fly   686 DWDASAQRIP-AQMPSISRLDTYAAKSRCSSVKETKKYCIC 725

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9525	NP_609260.1	DUF229	66..554	CDD:281053	150/517 (29%)
CG9525	NP_609260.1	ALP_like	206..466	CDD:293745	93/279 (33%)
CG15695	NP_650920.3	DUF229	180..656	CDD:281053	152/523 (29%)
CG15695	NP_650920.3	ALP_like	293..571	CDD:293745	94/280 (34%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45469440
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_28JJT
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D31599at6960
OrthoFinder	1	1.000	-	-		FOG0005924
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR10974
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	6	5.850