DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG9525 and F07C3.3

DIOPT Version :9

Sequence 1:	NP_609260.1	Gene:	CG9525 / 34217	FlyBaseID:	FBgn0032080	Length:	678	Species:	Drosophila melanogaster
Sequence 2:	NP_505391.4	Gene:	F07C3.3 / 184124	WormBaseID:	WBGene00017194	Length:	746	Species:	Caenorhabditis elegans

Alignment Length:	705	Identity:	141/705 - (20%)
Similarity:	258/705 - (36%)	Gaps:	198/705 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly    34 HEHYI------KTSECHIPYINKPLENEKGNIKKQHTICSKDESLINLRFDEKSHQYLLYVNDHV 92
            |.|::      :..:|.:..|       :|.::|.....:|:...|....:..|:: .|:||...
Worm   142 HPHFVDWPRLERDVQCKVDII-------EGGLRKPERNMTKNSMFIKKTLEIPSNE-RLFVNADA 198

  Fly    93 AQLKLRSMKKKS--PNLIGYNCSYRELKRLNRDYIVDAPVVYVCYLTDRSLKFEDQFLYSLGEEV 155
            ..:...:..||:  |.:..:...:..:|..|..             .|..|:.:|  |||.|:
Worm   199 FVINCYNHSKKAVKPEVPIWKKPFPGMKDKNLP-------------EDEILRVKD--LYSYGD-- 246

  Fly   156 KFWNGYIVPPSVEGMRATCRNELAEDLQS--DTFVLVQPPKTYAPLISWHRIPNVLLIGFDGISQ 218
                              ..|::.|.:..  |.:                   ::.::|||..::
Worm   247 ------------------YGNKIREQVSKAVDRY-------------------SIDILGFDSTAR 274

  Fly   219 INFRRNFPLVFNQLKMQDWFRMDGYTGIGENTQSNLMASLTGYSPHTLMNLKCDSS----VIGCL 279
            ..|.|:.|.....:...|:..:.|||.:.:|:..||...|.|.....|...|.|.|    :...|
Worm   275 TMFMRHMPRTVEVMAKLDYHYLYGYTKVADNSMVNLAPILVGDMEEALKKPKYDKSGDFNINWLL 339

  Fly   280 KT--------VPLIWKHFKKK-GFITAYGEGIS----NLFD----SEKYGIFEGTIDFYAR---- 323
            .|        :..:||..|:| |..:.:.|.||    .||:    ..:.|..|...|.|.|
Worm   340 PTEDKMDPTKLNFLWKIMKEKYGCESLFNEDISTKGLGLFNYPPTEFQPGFTENPADHYYRAYYL 404

  Fly   324 --HKN--LQSCID------------RRFNIKHNY-DYCEEFLKRHANTNRPFFGVFFGNGITNRS 371
              ::|  .::|.|            |||  .|.| :.|.             ||..|...:|:
Worm   405 AVYENWKYEACRDGEQLQNEFVNIWRRF--AHRYRNICH-------------FGFTFVTTLTH-- 452

  Fly   372 YDNARIQTELLDK-----VKKFKKMGILTQSIVVLF---SYPVSSVKEKKTNFSQEDLPILYIWL 428
              .|.:..|:||:     :.:....|.|..::.::.   ...:.::|.:.|...:|.:|::.:..
Worm   453 --EAGLVLEILDEKLAAHLSQMHLNGDLDNTLSIIMGDHGNRIGAIKSRYTGRIEERMPLMAMRF 515

  Fly   429 PPWFKAFRPEIVQALRINSKRLTSPYDLHLTLQHL--LELGERWPRAVDKLVDCPTCQTLFAPVP 491
            |..|....|...:....|..:|||.:|:|.||..:  :.||:...::     |.....:||..:|
Worm   516 PTGFAETYPVEYKNFLDNKHKLTSNFDVHKTLHDIVHMRLGDNKAKS-----DEGRGISLFDAIP 575

  Fly   492 ENRTCSDAGIGESQCPC------DSYKLLSSNQMKQLSVGKQIVRSINEFLNHHNLHELCHNLTL 550
            ..|||:|..:.|:.|.|      .:..|.:.|:.|..........::..:|...||.: |.:::
Worm   576 NTRTCADVIVPENFCMCMIDVSSIANPLPNFNKKKPTDQKMDQFNTLKSWLKTENLDD-CVDVS- 638

  Fly   551 KSVKMVLQRKDRKLSSGSTYRAYFSANP---------NNAEFSTTIRYANNRQ-ELEYINVE-SI 604
                        .|.:|.|::. .:.||         |||.....::..|.:. ||.|||.| |:
Worm   639 ------------SLETGQTFQE-MAINPLSRFGLRTKNNASMLELMKERNKKNPELNYINFEFSV 690

  Fly   605 NRLNNYQNDSSCMRRLRGRKFCICKSQILENHSTSEVTKLIPNKNKIDDKLYELP 659
            :  ..|:|.......:|        :::....|||::.        .:..:.|:|
Worm   691 S--GTYKNGEPLSMLVR--------TELFVEKSTSQLI--------FEPMIQEMP 727

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9525	NP_609260.1	DUF229	66..554	CDD:281053	111/549 (20%)
CG9525	NP_609260.1	ALP_like	206..466	CDD:293745	70/311 (23%)
F07C3.3	NP_505391.4	DUF229	75..623	CDD:308570	113/566 (20%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160165304
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_28JJT
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.740