DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment C1GalTA and c1galt1b

DIOPT Version :9

Sequence 1:	NP_609258.1	Gene:	C1GalTA / 34215	FlyBaseID:	FBgn0032078	Length:	388	Species:	Drosophila melanogaster
Sequence 2:	NP_956345.1	Gene:	c1galt1b / 337131	ZFINID:	ZDB-GENE-030131-9075	Length:	374	Species:	Danio rerio

Alignment Length:	375	Identity:	163/375 - (43%)
Similarity:	219/375 - (58%)	Gaps:	33/375 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    27 VGLIVGFCLAELFVYSTPERSEFMPYDGHRHGDVNDAHHSHDMMEMSGPEQ-----------DVG 80
            ||.:||.|    .:|....::.|....|.|    ....|...::||...|.           ::.
Zfish    12 VGFLVGTC----SLYLLLRQAGFTRDSGSR----EPGTHDKTLLEMLEEENKNWKKERSALFNLN 68

  Fly    81 GHEHVHENSTIAERLYSEVRVLCWIMTNPSNHQKKARHVKRTWGKRCNKLIFMSSAKDDELDAVA 145
            ...|..|:..:|:.||..||:|||:||.|.|.:|||||||.||.:.||.::|:||..:.:...|.
Zfish    69 HPHHTGEDGALADSLYKRVRILCWVMTGPDNLEKKARHVKATWSRHCNIVVFISSVDNPDFPTVG 133

  Fly   146 LPVGEGRNNLWGKTKEAYKYIYEHHINDADWFLKADDDTYTIVENMRYMLYPYSPETPVYFGCKF 210
            |...|||:.|:.||..|:.|:.|.|.::||||||||||||.||:|:|::|..:|||.|||||.:|
Zfish   134 LNTKEGRDQLYWKTIRAFHYVMEKHSDEADWFLKADDDTYVIVDNLRWILARHSPEDPVYFGRRF 198

  Fly   211 KPYVKQGYMSGGAGYVLSREAVRRFVVEALPNPKLCKSDNSGAEDVEIGKCLQNVNVLAGDSRDS 275
            ||||||||||||||||||:||:||| ||.. ..|:| :..:..||:.:|:|::.:.|.||||||:
Zfish   199 KPYVKQGYMSGGAGYVLSKEALRRF-VEGF-RTKVC-THTTSVEDLAMGQCMEKIGVKAGDSRDT 260

  Fly   276 NGRGRFFPFVPEHHLIPSHTDKKFWYWQYIFYKTDEGLDCCSDNAISFHYVSPNQMYVLDYLIYH 340
            ..|..|.|||||.||..:. .|.||||.|.:|...:|..||||.|:|||||..:.||:|:|..||
Zfish   261 MQRETFHPFVPESHLTGTF-PKTFWYWNYCYYPIVQGPQCCSDLAVSFHYVDASHMYLLEYYTYH 324

  Fly   341 LRPYGI---INTPDALPNKLAVGELMPEIKEQATESTSDGVSKRSAETKT 387
            ||.:|.   ...|:  ||..|     ||..|.......|.|..:..|.::
Zfish   325 LRAFGYKYRYQPPE--PNVKA-----PEKVETRVLEQKDKVEAQEEENQS 367

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
C1GalTA	NP_609258.1	Galactosyl_T	119..>265	CDD:304462	78/145 (54%)
c1galt1b	NP_956345.1	Galactosyl_T	107..274	CDD:304462	92/169 (54%)
c1galt1b	NP_956345.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	355..374		3/13 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	173	1.000	Domainoid score	I3636
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	314	1.000	Inparanoid score	I2547
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1407357at2759
OrthoFinder	1	1.000	-	-		FOG0000473
OrthoInspector	1	1.000	-	-		mtm6507
orthoMCL	1	0.900	-	-		OOG6_103571
Panther	1	1.100	-	-	O	PTHR23033
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2430
SonicParanoid	1	1.000	-	-		X502
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	12	11.960