Protein Alignment Tsp29Fb and UPK1B

DIOPT Version :10

• Sequence 1: NP_523516.1
• Gene: Tsp29Fb / 34212
• FlyBaseID: FBgn0032075
• Length: 308
• Species: Drosophila melanogaster
• Sequence 2: NP_008883.2
• Gene: UPK1B / 7348
• HGNCID: 12578
• Length: 260
• Species: Homo sapiens
• Alignment Length: 263
• Identity: 66/263 - (25%)
• Similarity: 108/263 - (41%)
• Gaps: 49/263 - (18%)

  Fly     9 NSGMKCAKYMLIIVSFMFALTAILLIMVGTTIQTIFGDFSLFIDGHFSSPPALL----------- 62
            ||.::|.:.:||..:.:.....|.|     |.:.||     |:....|..|.|.
Human     5 NSTVRCFQGLLIFGNVIIGCCGIAL-----TAECIF-----FVSDQHSLYPLLEATDNDDIYGAA 59

  Fly    63 ---IAIGFILIAVAALGAYGAVKESVMVINLYGVCLFLVFILEVSAAIAAFVMQSQVRGMLIRTM 124
               |.:|..|..::.||..|.:|.|..::..|.:.:|:|:..||::.|.|...|......|.  :
Human    60 WIGIFVGICLFCLSVLGIVGIMKSSRKILLAYFILMFIVYAFEVASCITAATQQDFFTPNLF--L 122

  Fly   125 NQALAEYEH-------DPYVESGV----DFMQSMLECCGVNEPEDWKDYLSANVNFTLGVDDVVV 178
            .|.|..|::       |.:..:||    |.:.....|||||.|.||:.|.||   |....:|...
Human   123 KQMLERYQNNSPPNNDDQWKNNGVTKTWDRLMLQDNCCGVNGPSDWQKYTSA---FRTENNDADY 184

  Fly   179 --PNSCC--GNQPTSLN-DSTQMTCMETY-DYGCFRKMNFIVSQSAMLIATGATTV---AFVQLL 234
              |..||  .|....|| ::.::.....| :.||:..::..:::.|..:|.....:   .|..||
Human   185 PWPRQCCVMNNLKEPLNLEACKLGVPGFYHNQGCYELISGPMNRHAWGVAWFGFAILCWTFWVLL 249

  Fly   235 GVL 237
            |.:
Human   250 GTM 252

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tsp29Fb	NP_523516.1	Tetraspanin	16..244	CDD:459767	63/256 (25%)
		tetraspanin_LEL	109..210	CDD:351888	32/117 (27%)
UPK1B	NP_008883.2	Tetraspanin	14..>161	CDD:459767	36/158 (23%)
		uroplakin_I_like_LEL	118..230	CDD:239409	30/116 (26%)