Protein Alignment Tsp29Fb and TSPAN6

DIOPT Version :10

• Sequence 1: NP_523516.1
• Gene: Tsp29Fb / 34212
• FlyBaseID: FBgn0032075
• Length: 308
• Species: Drosophila melanogaster
• Sequence 2: NP_003261.1
• Gene: TSPAN6 / 7105
• HGNCID: 11858
• Length: 245
• Species: Homo sapiens
• Alignment Length: 257
• Identity: 77/257 - (29%)
• Similarity: 128/257 - (49%)
• Gaps: 29/257 - (11%)

  Fly     3 NRELQLNSGMKCAKYMLIIVSFMFALTAILLIMVGTTIQTIFGDFSLFIDGHFS-------SPPA 60
            :|.||....:.|.|.:|:|.:|:|.:|.::|:.||     |:|..||  :.:||       :.|.
Human     5 SRRLQTKPVITCFKSVLLIYTFIFWITGVILLAVG-----IWGKVSL--ENYFSLLNEKATNVPF 62

  Fly    61 LLIAIGFILIAVAALGAYGAVKESVMVINLYGVCLFLVFILEVSAAIAAFVMQSQVRGMLIRTMN 125
            :|||.|.::|.:...|.:...:.|..::.||.:.|.|||::|:.|||..||.:.:::........
Human    63 VLIATGTVIILLGTFGCFATCRASAWMLKLYAMFLTLVFLVELVAAIVGFVFRHEIKNSFKNNYE 127

  Fly   126 QALAEYEH-DPYVESGVDFMQSMLECCGVNEPEDWKDYLSANVNFTLGVDDVVVPNSCCGNQPTS 189
            :||.:|.. ..|....||.:|:.|.||||.:..||.|     .|:   ..:...|.|||     .
Human   128 KALKQYNSTGDYRSHAVDKIQNTLHCCGVTDYRDWTD-----TNY---YSEKGFPKSCC-----K 179

  Fly   190 LNDST-QMTCMETYDYGCFRKMNFIVSQSAMLIATGATTVAFVQLLGVLCAFMLAKTLRRNK 250
            |.|.| |....:..:.|||.|:..|:.....::|..:..||..||:|:..|:.|::.:..|:
Human   180 LEDCTPQRDADKVNNEGCFIKVMTIIESEMGVVAGISFGVACFQLIGIFLAYCLSRAITNNQ 241

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tsp29Fb	NP_523516.1	Tetraspanin	16..244	CDD:459767	72/236 (31%)
		tetraspanin_LEL	109..210	CDD:351888	29/102 (28%)
TSPAN6	NP_003261.1	Tetraspanin	17..235	CDD:459767	72/237 (30%)
		TM4SF2_6_like_LEL	112..209	CDD:239414	31/109 (28%)