Protein Alignment Tsp29Fb and TSPAN7

DIOPT Version :10

• Sequence 1: NP_523516.1
• Gene: Tsp29Fb / 34212
• FlyBaseID: FBgn0032075
• Length: 308
• Species: Drosophila melanogaster
• Sequence 2: NP_004606.2
• Gene: TSPAN7 / 7102
• HGNCID: 11854
• Length: 249
• Species: Homo sapiens
• Alignment Length: 254
• Identity: 70/254 - (27%)
• Similarity: 126/254 - (49%)
• Gaps: 13/254 - (5%)

  Fly     1 MSNRELQLNSGMKCAKYMLIIVSFMFALTAILLIMVGTTIQTIFGDFSLFIDGHFSSPPALLIAI 65
            |::|.::....:.|.|.:|||.||:|.:|.::|:.||...:...|.:...|..:.::.|.:||..
Human     1 MASRRMETKPVITCLKTLLIIYSFVFWITGVILLAVGVWGKLTLGTYISLIAENSTNAPYVLIGT 65

  Fly    66 GFILIAVAALGAYGAVKESVMVINLYGVCLFLVFILEVSAAIAAFVMQSQVRGMLIRTMNQALAE 130
            |..::.....|.:...:.|..::.||.:.|.|||:.|:.|.|:.||.:.:::...:||...|:..
Human    66 GTTIVVFGLFGCFATCRGSPWMLKLYAMFLSLVFLAELVAGISGFVFRHEIKDTFLRTYTDAMQT 130

  Fly   131 YEHDPYVESGVDFMQSMLECCGVNEPEDWKDYLSANVNFTLGVDDVVVPNSCCGNQ----PTSLN 191
            |..:......||.:|..|.||||....:|    |.:..|.    :..:|.|||.|:    |..|:
Human   131 YNGNDERSRAVDHVQRSLSCCGVQNYTNW----STSPYFL----EHGIPPSCCMNETDCNPQDLH 187

  Fly   192 DSTQMTCMETYDYGCFRKMNFIVSQSAMLIATGATTVAFVQLLGVLCAFMLAKTLRRNK 250
            :.| :...:....||:..:...:..:..:||..|..:||.||:|:|.|..|::.:..|:
Human   188 NLT-VAATKVNQKGCYDLVTSFMETNMGIIAGVAFGIAFSQLIGMLLACCLSRFITANQ 245

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tsp29Fb	NP_523516.1	Tetraspanin	16..244	CDD:459767	66/231 (29%)
		tetraspanin_LEL	109..210	CDD:351888	27/104 (26%)
TSPAN7	NP_004606.2	Tetraspanin	15..239	CDD:459767	66/232 (28%)
		TM4SF2_6_like_LEL	110..213	CDD:239414	27/111 (24%)