Protein Alignment Tsp29Fb and ROM1

DIOPT Version :10

• Sequence 1: NP_523516.1
• Gene: Tsp29Fb / 34212
• FlyBaseID: FBgn0032075
• Length: 308
• Species: Drosophila melanogaster
• Sequence 2: NP_000318.2
• Gene: ROM1 / 6094
• HGNCID: 10254
• Length: 351
• Species: Homo sapiens
• Alignment Length: 304
• Identity: 72/304 - (23%)
• Similarity: 113/304 - (37%)
• Gaps: 69/304 - (22%)

  Fly    19 LIIVSFMFALT-AILLIMVGTTIQTI--FGDFSLFIDGHFSSPPALLIAIGFILIAVAALGAYGA 80
            |.::|::.||. .::|:..|..:..:  .|.| |.....|...|...:|.|.:.:....:|. ||
Human    21 LWLLSWLLALAGGVILLCSGHLLVQLRHLGTF-LAPSCQFPVLPQAALAAGAVALGTGLVGV-GA 83

  Fly    81 VKES---------------VMVINLYGVCLFLVFILEVSAAIAAFVMQSQVRGMLIRTMNQALAE 130
            .:.|               ::|....|....||..|.::.|:...:.::...|::     .|||.
Human    84 SRASLNAALYPPWRGVLGPLLVAGTAGGGGLLVVGLGLALALPGSLDEALEEGLV-----TALAH 143

  Fly   131 YEHDPYVESG------VDFMQSMLECCGVNEPEDW------------------KDYLSANVNFTL 171
            |: |..|...      ||.:|....|||.:..:||                  .|.:.:||....
Human   144 YK-DTEVPGHCQAKRLVDELQLRYHCCGRHGYKDWFGVQWVSSRYLDPGDRDVADRIQSNVEGLY 207

  Fly   172 GVDDVVVPNSCCGNQPTSLNDSTQMTCMETYDYGCF--RKMNFIVSQSAMLIATGATTVAF--VQ 232
            ..|.  ||.|||  .|.|.....|....::|.:..|  |:.|      ..|.|.|...|..  :|
Human   208 LTDG--VPFSCC--NPHSPRPCLQNRLSDSYAHPLFDPRQPN------QNLWAQGCHEVLLEHLQ 262

  Fly   233 LLGVLCAFMLAKTLRRNKSIREARRWQLQQSL----GVLISGGK 272
            .|......|||.|......:....|: ||.:|    ||:.:||:
Human   263 DLAGTLGSMLAVTFLLQALVLLGLRY-LQTALEGLGGVIDAGGE 305

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tsp29Fb	NP_523516.1	Tetraspanin	16..244	CDD:459767	62/270 (23%)
		tetraspanin_LEL	109..210	CDD:351888	30/126 (24%)
ROM1	NP_000318.2	peripherin_like_LEL	126..265	CDD:239415	36/154 (23%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	331..351