Protein Alignment Tsp29Fb and TSPAN33

DIOPT Version :10

• Sequence 1: NP_523516.1
• Gene: Tsp29Fb / 34212
• FlyBaseID: FBgn0032075
• Length: 308
• Species: Drosophila melanogaster
• Sequence 2: NP_848657.1
• Gene: TSPAN33 / 340348
• HGNCID: 28743
• Length: 283
• Species: Homo sapiens
• Alignment Length: 254
• Identity: 63/254 - (24%)
• Similarity: 117/254 - (46%)
• Gaps: 33/254 - (12%)

  Fly    16 KYMLIIVSFMFALTAILLIMVGTTIQTIFGDFSLFIDGHFS----SPPALLIAIGFILIAVAALG 76
            ||:|...:.:|.:.:::::.||     ::.......:...:    .|..|||.:|.::..:...|
Human    23 KYLLFFFNMLFWVISMVMVAVG-----VYARLMKHAEAALACLAVDPAILLIVVGVLMFLLTFCG 82

  Fly    77 AYGAVKESVMVINLYGVCLFLVFILEVSAAIAAFVMQSQVRGMLIRTMNQALAEYEHDPYVESGV 141
            ..|:::|::.::..:.:||..||:|:::|.|..||...:.||.:...:|.|:..|..|..:::.:
Human    83 CIGSLRENICLLQTFSLCLTAVFLLQLAAGILGFVFSDKARGKVSEIINNAIVHYRDDLDLQNLI 147

  Fly   142 DFMQSMLECCGVNEPEDWKDYLSANVNFTLGVDD-----VVVPNSCCGNQPTSLNDSTQMTC--- 198
            ||.|....|||....:||    |.|:.|....|:     ..||.|||  .||.........|
Human   148 DFGQKKFSCCGGISYKDW----SQNMYFNCSEDNPSRERCSVPYSCC--LPTPDQAVINTMCGQG 206

  Fly   199 METYDY----------GCFRKMNFIVSQSAMLIATGATTVAFVQLLGVLCAFMLAKTLR 247
            |:.:||          ||..|:...:..:..|:...|..:|..||:|:|.:.:|...::
Human   207 MQAFDYLEASKVIYTNGCIDKLVNWIHSNLFLLGGVALGLAIPQLVGILLSQILVNQIK 265

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tsp29Fb	NP_523516.1	Tetraspanin	16..244	CDD:459767	63/249 (25%)
		tetraspanin_LEL	109..210	CDD:351888	33/118 (28%)
TSPAN33	NP_848657.1	Tetraspanin	22..262	CDD:459767	63/249 (25%)
		penumbra_like_LEL	116..236	CDD:239411	34/125 (27%)