Protein Alignment Tsp29Fb and UPK1A

DIOPT Version :10

• Sequence 1: NP_523516.1
• Gene: Tsp29Fb / 34212
• FlyBaseID: FBgn0032075
• Length: 308
• Species: Drosophila melanogaster
• Sequence 2: XP_054175633.1
• Gene: UPK1A / 11045
• HGNCID: 12577
• Length: 313
• Species: Homo sapiens
• Alignment Length: 214
• Identity: 51/214 - (23%)
• Similarity: 81/214 - (37%)
• Gaps: 38/214 - (17%)

  Fly    33 LIMVGTTIQTIFGDFSLF------------------IDGHFSSPPALLIAI--GFILIAVAALGA 77
            |::||..|..:.| .|||                  :.|.........|||  ||....||:.|.
Human    20 LLVVGNIIILLSG-LSLFAETIWVTADQYRVYPLMGVSGKDDVFAGAWIAIFCGFSFFMVASFGV 83

  Fly    78 YGAVKESVMVINLYGVCLFLVFILEVSAAIAAFVMQSQVRGMLIRTMNQALAEYEHDPYVESGV- 141
            ..|:.....::..|.|.:.:|:|.|.::.|.::..:..:.........|.|..|..|  .:.|.
Human    84 GAALCRRRSMVLTYLVLMLIVYIFECASCITSYTHRDYMVSNPSLITKQMLTFYSAD--TDQGQE 146

  Fly   142 -----DFMQSMLECCGVNEPEDWKDYLSANVNFTLGVDDVVV--PNSCC---GNQPTSLNDSTQM 196
                 |.:....||||.:.|.||.::.||   |.....:||.  |..||   ||......:..::
Human   147 LTRLWDRVMIEQECCGTSGPMDWVNFTSA---FRAATPEVVFPWPPLCCRRTGNFIPLNEEGCRL 208

  Fly   197 TCME-TYDYGCFRKMNFIV 214
            ..|: .:..|||..:...:
Human   209 GHMDYLFTKGCFEHIGHAI 227

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tsp29Fb	NP_523516.1	Tetraspanin	16..244	CDD:459767	51/214 (24%)
		tetraspanin_LEL	109..210	CDD:351888	27/112 (24%)
UPK1A	XP_054175633.1	Tetraspanin	25..>163	CDD:459767	30/140 (21%)
		uroplakin_I_like_LEL	113..231	CDD:239409	28/120 (23%)