Protein Alignment Tsp29Fb and TSPAN2

DIOPT Version :10

• Sequence 1: NP_523516.1
• Gene: Tsp29Fb / 34212
• FlyBaseID: FBgn0032075
• Length: 308
• Species: Drosophila melanogaster
• Sequence 2: NP_005716.2
• Gene: TSPAN2 / 10100
• HGNCID: 20659
• Length: 221
• Species: Homo sapiens
• Alignment Length: 259
• Identity: 59/259 - (22%)
• Similarity: 108/259 - (41%)
• Gaps: 54/259 - (20%)

  Fly     7 QLNSGMKCAKYMLIIVSFMFALTAILLIMVGTTIQTIFGDFSLFIDGHFSSPP------ALLIAI 65
            :...|::|.||:|:..:.:|.|....:|..|...:  ||.....:.....||.      .:|:..
Human     3 RFRGGLRCIKYLLLGFNLLFWLAGSAVIAFGLWFR--FGGAIKELSSEDKSPEYFYVGLYVLVGA 65

  Fly    66 GFILIAVAALGAYGAVKESVMVINLYGVCLFLVFILEVSAAIAAFVMQSQVRGMLIRTMNQALAE 130
            |.:::||...|..||::||..|:..:..||.::|..||:..:.||:    .:|:.||
Human    66 GALMMAVGFFGCCGAMRESQCVLGSFFTCLLVIFAAEVTTGVFAFI----GKGVAIR-------- 118

  Fly   131 YEHDPYVESGVDFMQSMLECCGVNEPEDWKDYLS--ANVNFTLGVDDVVVPNS---CCGNQPTSL 190
                        .:|:|.|       |.:.|||.  ...|.||     :..:|   |||.:.
Human   119 ------------HVQTMYE-------EAYNDYLKDRGKGNGTL-----ITFHSTFQCCGKES--- 156

  Fly   191 NDSTQMTCMETY--DYGCFRKMNFIVSQSAMLIATGATTVAFVQLLGVLCAFMLAKTLRRNKSI 252
            ::..|.||.:..  ...|..::..|:|....||......:|.:.:.|::.:.:|...:|.::.:
Human   157 SEQVQPTCPKELLGHKNCIDEIETIISVKLQLIGIVGIGIAGLTIFGMIFSMVLCCAIRNSRDV 220

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tsp29Fb	NP_523516.1	Tetraspanin	16..244	CDD:459767	56/240 (23%)
		tetraspanin_LEL	109..210	CDD:351888	23/107 (21%)
TSPAN2	NP_005716.2	Tetraspanin	11..212	CDD:459767	56/241 (23%)
		CD81_like_LEL	110..186	CDD:239404	24/114 (21%)