Protein Alignment Tsp29Fa and TSPAN10

DIOPT Version :10

• Sequence 1: NP_523515.1
• Gene: Tsp29Fa / 34211
• FlyBaseID: FBgn0032074
• Length: 248
• Species: Drosophila melanogaster
• Sequence 2: NP_114151.3
• Gene: TSPAN10 / 83882
• HGNCID: 29942
• Length: 355
• Species: Homo sapiens
• Alignment Length: 264
• Identity: 69/264 - (26%)
• Similarity: 106/264 - (40%)
• Gaps: 29/264 - (10%)

  Fly     2 SLLTGSANAVKYTLFGFNLIFLITGIILIAVGAGVGAVYTGYKLFLAGKFFSIPTFLIVIGSFII 66
            ||..|| :.|||.:|..|..|.:.|::.:|:|....||.......|.|...:.|...:.:|..::
Human    68 SLSPGS-SCVKYLIFLSNFPFSLLGLLALAIGLWGLAVKGSLGSDLGGPLPADPMLGLALGGLVV 131

  Fly    67 -IISFFGCWGALKENYCLVLSFSVMLAIIFILELAAGISGYVLRNDASDLIKTSLTYSLNEYNSI 130
             .:|..|..|||.||.||:..||..:....:||..||.....|.....|.::.:|..::..|..
Human   132 SAVSLAGYLGALCENTCLLRGFSGGILAFLVLEAVAGALVVALWGPLQDSLEHTLRVAIAHYQD- 195

  Fly   131 NPNATTKLWDDIQDEFECCGVTSYNDW-----ITAFPNG----DLPISCC----------NVHVG 176
            :|:... |.|.:|....|||..||.||     ......|    .||.|||          |...|
Human   196 DPDLRF-LLDQVQLGLRCCGAASYQDWQQNLYFNCSSPGVQACSLPASCCIDPREDGASVNDQCG 259

  Fly   177 AVGTFTCNNAQSSVADR--HKVGCLDGFSGYISAHAVSLGAAGVVIAILQFFGVIFACYIAREIK 239
                |......:..|.|  :..||......::.|:..:.|...:.:.:||...::.|..:...:.
Human   260 ----FGVLRLDADAAQRVVYLEGCGPPLRRWLRANLAASGGYAIAVVLLQGAELLLAARLLGALA 320

  Fly   240 IRNG 243
            .|.|
Human   321 ARRG 324

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tsp29Fa	NP_523515.1	Tetraspanin	11..236	CDD:459767	63/246 (26%)
		tetraspanin_LEL	126..201	CDD:351888	25/95 (26%)
TSPAN10	NP_114151.3	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..33
		Tetraspanin	76..226	CDD:459767	45/151 (30%)
		oculospanin_like_LEL	172..291	CDD:239420	29/124 (23%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	327..355