Protein Alignment Tsp29Fa and TSPAN6

DIOPT Version :10

• Sequence 1: NP_523515.1
• Gene: Tsp29Fa / 34211
• FlyBaseID: FBgn0032074
• Length: 248
• Species: Drosophila melanogaster
• Sequence 2: NP_003261.1
• Gene: TSPAN6 / 7105
• HGNCID: 11858
• Length: 245
• Species: Homo sapiens
• Alignment Length: 236
• Identity: 68/236 - (28%)
• Similarity: 109/236 - (46%)
• Gaps: 25/236 - (10%)

  Fly    12 KYTLFGFNLIFLITGIILIAVGAGVGAVYTGYKLFLAGKFFSIPTFLIVIGSFIIIISFFGCWGA 76
            |..|..:..||.|||:||:|||.........|...|..|..::|..||..|:.||::..|||:..
Human    18 KSVLLIYTFIFWITGVILLAVGIWGKVSLENYFSLLNEKATNVPFVLIATGTVIILLGTFGCFAT 82

  Fly    77 LKENYCLVLSFSVMLAIIFILELAAGISGYVLRNDASDLIKTSLTYSLNEYNSINPNATTKLWDD 141
            .:.:..::..:::.|.::|::||.|.|.|:|.|::..:..|.:...:|.:|||.....:..: |.
Human    83 CRASAWMLKLYAMFLTLVFLVELVAAIVGFVFRHEIKNSFKNNYEKALKQYNSTGDYRSHAV-DK 146

  Fly   142 IQDEFECCGVTSYNDWITA--FPNGDLPISCCNVHVGAVGTFTCNNAQSSVADR-HKVGCLDGFS 203
            ||:...|||||.|.||...  :.....|.|||.:.       .|...:.  ||: :..||
Human   147 IQNTLHCCGVTDYRDWTDTNYYSEKGFPKSCCKLE-------DCTPQRD--ADKVNNEGC----- 197

  Fly   204 GYISAHAVSLGAAGVV------IAILQFFGVIFACYIAREI 238
             :|....:.....|||      :|..|..|:..|..::|.|
Human   198 -FIKVMTIIESEMGVVAGISFGVACFQLIGIFLAYCLSRAI 237

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tsp29Fa	NP_523515.1	Tetraspanin	11..236	CDD:459767	66/232 (28%)
		tetraspanin_LEL	126..201	CDD:351888	23/77 (30%)
TSPAN6	NP_003261.1	Tetraspanin	17..235	CDD:459767	66/232 (28%)
		TM4SF2_6_like_LEL	112..209	CDD:239414	28/112 (25%)