Protein Alignment Tsp29Fa and TSPAN33

DIOPT Version :10

• Sequence 1: NP_523515.1
• Gene: Tsp29Fa / 34211
• FlyBaseID: FBgn0032074
• Length: 248
• Species: Drosophila melanogaster
• Sequence 2: NP_848657.1
• Gene: TSPAN33 / 340348
• HGNCID: 28743
• Length: 283
• Species: Homo sapiens
• Alignment Length: 255
• Identity: 76/255 - (29%)
• Similarity: 124/255 - (48%)
• Gaps: 37/255 - (14%)

  Fly    11 VKYTLFGFNLIFLITGIILIAVGAGVGAVYTGY----KLFLAGKFFSIPTFLIVIGSFIIIISFF 71
            |||.||.||::|.:..::::|||     ||...    :..||.........|||:|..:.:::|.
Human    22 VKYLLFFFNMLFWVISMVMVAVG-----VYARLMKHAEAALACLAVDPAILLIVVGVLMFLLTFC 81

  Fly    72 GCWGALKENYCLVLSFSVMLAIIFILELAAGISGYVL----RNDASDLIKTSLTYSLNEYNSINP 132
            ||.|:|:||.||:.:||:.|..:|:|:|||||.|:|.    |...|::|..::.:..::.:..|
Human    82 GCIGSLRENICLLQTFSLCLTAVFLLQLAAGILGFVFSDKARGKVSEIINNAIVHYRDDLDLQN- 145

  Fly   133 NATTKLWDDIQDEFECCGVTSYNDWITAF--------PNGD---LPISCC--NVHVGAVGTFTCN 184
                 |.|..|.:|.|||..||.||....        |:.:   :|.|||  ......:.|....
Human   146 -----LIDFGQKKFSCCGGISYKDWSQNMYFNCSEDNPSRERCSVPYSCCLPTPDQAVINTMCGQ 205

  Fly   185 NAQS-SVADRHKV----GCLDGFSGYISAHAVSLGAAGVVIAILQFFGVIFACYIAREIK 239
            ..|: ...:..||    ||:|....:|.::...||...:.:||.|..|::.:..:..:||
Human   206 GMQAFDYLEASKVIYTNGCIDKLVNWIHSNLFLLGGVALGLAIPQLVGILLSQILVNQIK 265

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tsp29Fa	NP_523515.1	Tetraspanin	11..236	CDD:459767	74/250 (30%)
		tetraspanin_LEL	126..201	CDD:351888	23/92 (25%)
TSPAN33	NP_848657.1	Tetraspanin	22..262	CDD:459767	74/250 (30%)
		penumbra_like_LEL	116..236	CDD:239411	29/125 (23%)