Protein Alignment Tsp29Fa and Tspan12

DIOPT Version :10

• Sequence 1: NP_523515.1
• Gene: Tsp29Fa / 34211
• FlyBaseID: FBgn0032074
• Length: 248
• Species: Drosophila melanogaster
• Sequence 2: NP_766595.1
• Gene: Tspan12 / 269831
• MGIID: 1889818
• Length: 305
• Species: Mus musculus
• Alignment Length: 260
• Identity: 66/260 - (25%)
• Similarity: 110/260 - (42%)
• Gaps: 43/260 - (16%)

  Fly     7 SANAVKYTLFGFNLIFLITGIILIAVGAGVGAVYTGYKLFLAGK-----------FFSIPTFLIV 60
            |...::..|:..||:|.:..|.::||.|.: ..|....|.|..:           |..:...:|.
Mouse     6 SVKCLRCLLYALNLLFWLMSISVLAVSAWM-RDYLNNVLTLTAETRVEEAVILTYFPVVHPVMIA 69

  Fly    61 IGSFIIIISFFGCWGALKENYCLVLSFSVMLAIIFILELAAGISGY----VLRNDASDLI--KTS 119
            :..|:||:...|..|.:|.|..|:..:...|.:||.:|||.|:..|    ::....||::  |..
Mouse    70 VCCFLIIVGMLGYCGTVKRNLLLLAWYFGTLLVIFCVELACGVWTYEQEVMVPVQWSDMVTLKAR 134

  Fly   120 LT-YSLNEYNSINPNATTKLWDDIQDEFECCGVTSYNDWITAFPNGDLPISCCNVHVGAVGTFT- 182
            :| |.|..|..:     |..|:..|.||:||||..:.||:........|.|||      |..|.
Mouse   135 MTNYGLPRYRWL-----THAWNYFQREFKCCGVVYFTDWLEMTEMDWPPDSCC------VREFPG 188

  Fly   183 CNNA--QSSVADRHKVGCLDGFSGYISAH---------AVSLGAAGVVIAILQFFGVIFACYIAR 236
            |:..  |..::|.::.||......::...         .:|:|...::..||. ..:::|.|..|
Mouse   189 CSKQAHQEDLSDLYQEGCGKKMYSFLRGTKQLQVLRFLGISIGVTQILAMILT-ITLLWALYYDR 252

  Fly   237  236
            Mouse   253  252

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tsp29Fa	NP_523515.1	Tetraspanin	11..236	CDD:459767	64/254 (25%)
		tetraspanin_LEL	126..201	CDD:351888	23/77 (30%)
Tspan12	NP_766595.1	Tetraspanin	10..246	CDD:459767	62/248 (25%)
		TM4SF12_like_LEL	116..218	CDD:239410	29/112 (26%)