Protein Alignment Tsp29Fa and TSPAN16

DIOPT Version :10

• Sequence 1: NP_523515.1
• Gene: Tsp29Fa / 34211
• FlyBaseID: FBgn0032074
• Length: 248
• Species: Drosophila melanogaster
• Sequence 2: NP_036598.1
• Gene: TSPAN16 / 26526
• HGNCID: 30725
• Length: 245
• Species: Homo sapiens
• Alignment Length: 239
• Identity: 56/239 - (23%)
• Similarity: 110/239 - (46%)
• Gaps: 20/239 - (8%)

  Fly     9 NAVKYTLFGFNLIFLITGIILIAVGAG---VGAVYTGYKLFLAGKFFSIPTFLIVIGSFIIIISF 70
            :::|..|...|....::||||:.:|.|   .||..|......:.....:....:|:|...:::..
Human     9 SSLKKLLSLLNGFVAVSGIILVGLGIGGKCGGASLTNVLGLSSAYLLHVGNLCLVMGCITVLLGC 73

  Fly    71 FGCWGALKENYCLVLSFSVMLAIIFILELAAG---ISGYVLRNDASDLIKTSLTYSLNEYNSIN- 131
            .|.:||.||:...:|...:.:.|:.|:|:.|.   :..:.:..|.: |..|.:|...| |...|
Human    74 AGWYGATKESRGTLLFCILSMVIVLIMEVTAATVVLLFFPIVGDVA-LEHTFVTLRKN-YRGYNE 136

  Fly   132 PNATTKLWDDIQDEFECCGVTSYNDWI-TAF---PNGDLPISCCNVHVGAVGTFTCNNAQSSVAD 192
            |:..:..|:.:.::.:||||.:|.|:. ::|   .....|.|||.    ::|:.:|:....|...
Human   137 PDDYSTQWNLVMEKLKCCGVNNYTDFSGSSFEMTTGHTYPRSCCK----SIGSVSCDGRDVSPNV 197

  Fly   193 RHKVGCLDGFSGYISAHAVSLGAAGVVIAILQFFGVIFACYIAR 236
            .|:.||...........:.:|..:.:..|::|.:|   :.|:|:
Human   198 IHQKGCFHKLLKITKTQSFTLSGSSLGAAVIQRWG---SRYVAQ 238

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tsp29Fa	NP_523515.1	Tetraspanin	11..236	CDD:459767	55/235 (23%)
		tetraspanin_LEL	126..201	CDD:351888	21/79 (27%)
TSPAN16	NP_036598.1	Tetraspanin	19..>155	CDD:459767	32/137 (23%)
		uroplakin_I_like_LEL	120..215	CDD:239409	25/99 (25%)