Protein Alignment Tsp29Fa and TSPAN1

DIOPT Version :10

• Sequence 1: NP_523515.1
• Gene: Tsp29Fa / 34211
• FlyBaseID: FBgn0032074
• Length: 248
• Species: Drosophila melanogaster
• Sequence 2: XP_011538762.1
• Gene: TSPAN1 / 10103
• HGNCID: 20657
• Length: 258
• Species: Homo sapiens
• Alignment Length: 229
• Identity: 67/229 - (29%)
• Similarity: 109/229 - (47%)
• Gaps: 20/229 - (8%)

  Fly    11 VKYTLFGFNLIFLITGIILIAVGAGV---GAVYTGYKLF-----LAGKFFSIPTFLIVIGSFIII 67
            :|..:..|||:..:.|..|:|||..|   ||.:  .|:|     .|.:|.::..|||..|..:..
Human     7 IKTMMILFNLLIFLCGAALLAVGIWVSIDGASF--LKIFGPLSSSAMQFVNVGYFLIAAGVVVFA 69

  Fly    68 ISFFGCWGALKENYCLVLSFSVMLAIIFILELAAGISGYVLRNDASDLIKTSLTYSL-NEYNSIN 131
            :.|.||:||..|:.|.:::|..:|.:|||.|:||.:...|....|...:...:..:: .:|.|
Human    70 LGFLGCYGAKTESKCALVTFFFILLLIFIAEVAAAVVALVYTTMAEHFLTLLVVPAIKKDYGS-- 132

  Fly   132 PNATTKLWDDIQDEFECCGVTSYNDWITAFP----NGDLPISCCNVHVGAVGTFTCNNAQSSVAD 192
            ....|::|:......:|||.|:|.|:..: |    |...|..|||.:|......||...::.  |
Human   133 QEDFTQVWNTTMKGLKCCGFTNYTDFEDS-PYFKENSAFPPFCCNDNVTNTANETCTKQKAH--D 194

  Fly   193 RHKVGCLDGFSGYISAHAVSLGAAGVVIAILQFF 226
            :...||.:.....|..:||::|.....|..|:||
Human   195 QKVEGCFNQLLYDIRTNAVTVGGVAAGIGGLEFF 228

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tsp29Fa	NP_523515.1	Tetraspanin	11..236	CDD:459767	67/229 (29%)
		tetraspanin_LEL	126..201	CDD:351888	22/78 (28%)
TSPAN1	XP_011538762.1	Tetraspanin	7..>151	CDD:459767	42/147 (29%)
		uroplakin_I_like_LEL	110..212	CDD:239409	24/106 (23%)