Protein Alignment LManVI and AMS1

DIOPT Version :10

• Sequence 1: NP_609253.1
• Gene: LManVI / 34206
• FlyBaseID: FBgn0032069
• Length: 1007
• Species: Drosophila melanogaster
• Sequence 2: NP_011359.1
• Gene: AMS1 / 852721
• SGDID: S000003124
• Length: 1083
• Species: Saccharomyces cerevisiae
• Alignment Length: 1066
• Identity: 188/1066 - (17%)
• Similarity: 351/1066 - (32%)
• Gaps: 374/1066 - (35%)

  Fly    37 MINIHMVPHSHDDVGWLKTVDQYFYGHRSNIQHAGVQYIIDTVIAELIKDPARRFIQVETSFFAK 101
            :.|::.:.:.|.|..||.   .:....|..::....|..:      :.:.|..:|:..:...| |
Yeast   288 LTNVYGIGNCHIDTAWLW---PFAETRRKIVRSWSSQCTL------MDRFPEYKFVASQAQQF-K 342

  Fly   102 WWAE-QSETAKQVVRKLVNEGRLEFTGGAWSMNDEAAVNYQSVIDQFTLGLKFLDDTFGSCARPR 165
            |..| ..|...:|:...:.:.:....||.|..||....:.:|:..||..|.:|....||  .:.:
Yeast   343 WLLEDHPEFFNKVLIPKIQQSQFFAVGGTWVENDTNIPSGESLARQFFFGQRFFLKHFG--LKSK 405

  Fly   166 IGWQIDPFGHSREQASIFAQMGYDGEFFARMDHRDKNDRIDNLGMEMIWDASDSLSNDEI-FTGL 229
            |.|..|.||:|.:...:....|.| :|               |..::.|:..:|..:... :.|:
Yeast   406 IFWLPDTFGYSSQMPQLCRLSGID-KF---------------LTQKLSWNNINSFPHSTFNWAGI 454

  Fly   230 ----LYRHYSAPPG--YCFDVHCGDDPIIDTKSYDNNVKSRVDDFLSYVTSVAQHYRSNHIMIPM 288
                |..|  .|||  |..|.|.||  ::.|...:               ...::|.|..::...
Yeast   455 DGSQLLTH--MPPGNTYTADSHFGD--VLRTAKQN---------------KTPEYYGSGLMLYGK 500

  Fly   289 GDDFQYEDAQVNFKNMDKL--IKYVNERQAE-------GSTFNLFYSTPACYLNSLHEGLQTWPN 344
            ||.......::    :.|:  |:.:|.|...       |.|.:.||.......|..|: |.||..
Yeast   501 GDGGGGPTEEM----LQKMRRIRSMNNRNGNVIPKLQVGITVDEFYDDILKRTNQGHD-LPTWSG 560

  Fly   345 KTQDFFPYGSDDNSYWTGYFTSRPTQKRFERDGN---HILQ-VAKQLSVFAELNTKQQKEDLEYL 405
            :.  :|       .:..|.:||:...|:..|...   |.|: :|.:.||....:.|...:.:..|
Yeast   561 EL--YF-------EFHRGTYTSQAQTKKLMRLSEIKLHDLEWIAAKTSVLYPDSYKYPSKQINEL 616

  Fly   406 REIMGVMQHHDAITGTEKQHVSDDYDRILYDAILGGVNTARDGLRKLTNLPNGEFESCLQLNISE 470
            .|.:.:.|.||.:.|                                         ||:::
Yeast   617 WENVLLCQFHDVLPG-----------------------------------------SCIEM---- 636

  Fly   471 CAFTKDDADNVVVTLYNPLAHTSTQYVRVPVKNENYEVTDEKGRVVASEVVPVAWQVLALEFRNN 535
                                                        |...|.||:.
Yeast   637 --------------------------------------------VYKYEAVPML----------- 646

  Fly   536 DTQHELVFKAS--VDKIANYYIKKVASQETKNVAAHTKSKRSIKAEEANLEVPKRFKKVHSLKNA 598
               |.:|.:.:  :||... :::..:..:...:...|.||....:||.:|.        .|..::
Yeast   647 ---HNVVKECTSLIDKTVQ-FLQSQSKADLVEMRTLTWSKPEKVSEECSLN--------GSYTSS 699

  Fly   599 TETFDDDEGETVVQTSQVKLVIDNKTGLLKTV--EMNGVSENIDQSYG----------VY----- 646
            ...:||   ..|:...::|::|..|||::.::  |..|| |.:|..:|          :|
Yeast   700 VTGYDD---YIVLANGKLKVIICKKTGVITSITDETLGV-EYLDTEHGRNKLGANQFVIYDDKPL 760

  Fly   647 --RTYDSGAYVFRQYHQADFIVQYEGVEFTVYDGALVKEVHQQFSEYISQVIRIY-----EGKNL 704
              :.:|:..|...||                              :|:::..::.     :.|..
Yeast   761 GWQAWDTELYSVNQY------------------------------KYVTKPKKVQVSCNTKEKCA 795

  Fly   705 VEIEWQVGPIEREEEFGREVVIIFNSTIASDG------VSYTDSNGREMIKRVKDQ-----RETF 758
            ||:.:|:     .|:...:.||..|:|..:|.      :|.|..|.....|.:|.:     |..|
Yeast   796 VEVIFQI-----SEKCKIKSVISLNATAVTDAKLSKVDISTTVENWDARNKFLKVEFPVNIRNDF 855

  Fly   759 TP-----GLDRQPTAANYYPVTSRIA-----------LQDSKKRIAVLNDRAQGGASMLNGQLEL 807
            ..     |:.::||   :|..:..:|           ..:..|.:::|||...|.::
Yeast   856 ASYETQFGITKRPT---HYNTSWDVAKFEVCHHKFADYSEYSKGVSILNDCKYGFST-------- 909

  Fly   808 MLHRRLVRDDGYGVGEALNEEKYGQPMIARGKVYLILSPSDESTAAEREAEKEIHLPFWKFFSKN 872
              |..|:|                        :.|:.||.    |.:..|:...|...:..:...
Yeast   910 --HGNLMR------------------------LSLLRSPK----APDAHADMGTHEIKYAIYPHR 944

  Fly   873 TGSTTAAAKSVPSFN-----DFPKSV-----HLLTLEPFNDDEVLLRVENFLDHTEGQVV--SFN 925
            ...::...|....||     ..||.:     .::::.  .|:.|:|  .|.....:...|  :::
Yeast   945 GALSSDTVKLAHEFNYCFKYKLPKDIGMNFDDIISIS--GDENVIL--SNIKRGEDDSAVKSNYS 1005

  Fly   926 IRP---------IFDYLNGVEIR--ETTLDGNLPLSDMKRFKFHHDSSGQKPDAVEYFTSAHKPL 979
            :.|         :::.|.|....  .|||       ::||.        :|.|.:|  ...:|.|
Yeast  1006 LNPRDEQSIVVRVYESLGGESFASLNTTL-------NLKRI--------EKVDNLE--MKVYKSL 1053

  Fly   980 AA---EQSQEASEFSVTLHPMQIRTF 1002
            .|   |.:...:...:.|.|.:|.:|
Yeast  1054 TATRDESNHAINRIPIKLRPFEIASF 1079

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
LManVI	NP_609253.1	GH38N_AMII_LAM_like	38..312	CDD:212121	57/283 (20%)
		PLN02701	40..898	CDD:178304	163/941 (17%)
AMS1	NP_011359.1	MngB	289..1081	CDD:440152	188/1065 (18%)