DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment LManVI and AT5G13980

DIOPT Version :9

Sequence 1:	NP_609253.1	Gene:	LManVI / 34206	FlyBaseID:	FBgn0032069	Length:	1007	Species:	Drosophila melanogaster
Sequence 2:	NP_196902.2	Gene:	AT5G13980 / 831246	AraportID:	AT5G13980	Length:	1024	Species:	Arabidopsis thaliana

Alignment Length:	1060	Identity:	386/1060 - (36%)
Similarity:	569/1060 - (53%)	Gaps:	107/1060 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 KYLCGIVLFVALLAISVRPSEEACGYEACPKTKTNMINIHMVPHSHDDVGWLKTVDQYFYGHRSN 66
            |:||.|||   ||.||:..|.... |..........:|:|:|||||||||||||||||:.|..::
plant     5 KFLCWIVL---LLGISLVESRYMV-YNTSHTIVPGKLNVHVVPHSHDDVGWLKTVDQYYVGSNNS 65

  Fly    67 IQHAGVQYIIDTVIAELIKDPARRFIQVETSFFAKWWAEQSETAKQVVRKLVNEGRLEFTGGAWS 131
            ||.|.||.::|:::..|:.|..|:||.||.:||.:||.||||..|::|::|::.|:||...|...
plant    66 IQVACVQNVLDSIVPALLADKNRKFIYVEQAFFQRWWNEQSEEIKRIVKELIHSGQLELINGGMC 130

  Fly   132 MNDEAAVNYQSVIDQFTLGLKFLDDTFGSCARPRIGWQIDPFGHSREQASIF-AQMGYDGEFFAR 195
            |:||||.:|..:|||.|||.:|:...|.  ..|||||||||||||..||.:. |::|:|..||.|
plant   131 MHDEAAPHYIDMIDQTTLGHRFIIREFN--VTPRIGWQIDPFGHSAVQAYLLGAEVGFDSVFFGR 193

  Fly   196 MDHRDKNDRIDNLGMEMIWDASDSL-SNDEIFTGLLYRHYSAPPGYCFDVHCGDDPII--DTKSY 257
            :|::|:..|.....:|:||..|.|| |:.:||.|....:|..|||..:.....|.|::  |...:
plant   194 IDYQDREKRYKEKTLEVIWRGSKSLGSSSQIFAGAFPTNYEPPPGGFYYEITDDSPVVQDDPDLF 258

  Fly   258 DNNVKSRVDDFLSYVTSVAQHYRSNHIMIPMGDDFQYEDAQVNFKNMDKLIKYVNERQAEGSTFN 322
            |.||:.||:.|::.....|...|.||||..||.||:|:.|...::.|||||.|||   .:|.. |
plant   259 DYNVQERVNAFVAAALDQANITRINHIMFTMGTDFRYQYAHTWYRQMDKLIHYVN---LDGRV-N 319

  Fly   323 LFYSTPACYLNSLHEGLQTWPNKTQDFFPYGSDDNSYWTGYFTSRPTQKRFERDGNHILQVAKQL 387
            .|||||:.|.::.|...:.||.||:|:|||....|:||||||||||..||:.|..:.....|:||
plant   320 AFYSTPSIYTDAKHAANEAWPLKTEDYFPYADRINAYWTGYFTSRPALKRYVRVMSAYYLAARQL 384

  Fly   388 SVFAELNTKQQKEDLEYLREIMGVMQHHDAITGTEKQHVSDDYDRILYDAILGGVNTARDGLRKL 452
            ..|.  ...|:..:.:.|.:.:.:.|||||::||.||||::||.:.|....:...:.....|..|
plant   385 EFFK--GRSQKGPNTDSLADALAIAQHHDAVSGTSKQHVANDYAKRLAIGYVEAESVVATSLAHL 447

  Fly   453 TNLP---NGEFESCLQLNISECAFTK---DDADNVVVTLYNPLAHTSTQYVRVPVKNENYEVTDE 511
            |.:.   |..|:.||.||||.|..::   .|..:::|..||||.......||:||...:..|.|.
plant   448 TKVDPTLNPTFQQCLLLNISYCPSSEVNLSDGKSLIVLAYNPLGWKRVDIVRLPVVGGDVSVHDS 512

  Fly   512 KGRVVASEVVPVAWQVLALE-------FRNNDTQ---HELVFKASVDKI--ANYYIKKVASQETK 564
            :|..|.|::||...:.:||.       ...:.||   :.|||..:|..:  ..|.|.  .:::|.
plant   513 EGHEVESQLVPFTDEYVALRKYHVEAYLGQSPTQVPKYWLVFSVTVPPLGFTTYTIS--TAKKTD 575

  Fly   565 NVAAHTKSKRSIKAEEANLEVPKRFKKVHSLKNATETFDDDEGETVVQTSQVKLVIDNKTGLLKT 629
            ..::.:.....:|.|::.:.:.....|:        :|..|:|..:       ..::.:|.:
plant   576 GYSSKSYVSNILKGEQSIINIGHGHLKL--------SFSTDQGTAI-------NYVNGRTSM--- 622

  Fly   630 VEMNGVSENIDQSYGVYRTY------------DSGAYVFRQYHQADFIVQYEG-VEFTVYDGALV 681
                  :|.:.|::..|..|            :|||||||.  ...|.:..|| |..||..|.||
plant   623 ------TEPVKQTFSYYSAYNGSNDKEPLIPQNSGAYVFRP--NGTFPINPEGQVPLTVIHGPLV 679

  Fly   682 KEVHQQFSEYISQVIRIYEGKNLVEIEWQVGPIEREEEFGREVVIIFNSTIASDGVSYTDSNGRE 746
            .|||||.:.:|||:.|:|:||..||:|:.||.|..::..|:|||...:|::.|:...||||:||:
plant   680 DEVHQQINPWISQITRVYKGKEHVEVEFIVGNIPIDDGIGKEVVTQISSSLKSNKTFYTDSSGRD 744

  Fly   747 MIKRVKDQRETFTPGLD-RQPTAANYYPVTSRIALQDSKKRIAVLNDRAQGGASMLNGQLELMLH 810
            .|||::|.|..:.  || .||.|.||||:...|.||||||..:|:.|||.||:|:::||:|||||
plant   745 YIKRIRDYRSDWK--LDVNQPIAGNYYPINHGIYLQDSKKEFSVMVDRAFGGSSIVDGQVELMLH 807

  Fly   811 RRLVRDDGYGVGEALNEEKYGQP----MIARGKVYLILSPSDESTAAEREAEKEIHLPFWKFFSK 871
            |||:.||..||.|.|||....|.    :..:||.|..:.|..|.....|...:||:.|....|::
plant   808 RRLLLDDSRGVAENLNETVCVQDKCTGLTIQGKYYYRIDPYGEGAKWRRTFGQEIYSPLLLAFAQ 872

  Fly   872 NTG----STTAAAKS--VPSFNDFPKSVHLLTLEPFNDDEVLLRVENFLDHTEGQ----VVSFNI 926
            ...    |..||:.|  .||:: .|.:|.||||:..:|..||||:.:..:..|.:    |.|..:
plant   873 QDDGKPMSFGAASFSGIDPSYS-LPDNVALLTLQELDDGNVLLRLAHLYEVEEDKELSGVASVEL 936

  Fly   927 RPIFDYLNGVEIRETTLDGNLPLSDM--KRFKFHHDSSGQKPDAVEYFTSAHKPLAAEQSQEAS- 988
            :.:|......::.|.:|..|...|.|  ||..:..:..|          |..:...|::.:|..
plant   937 KKLFPGKKIGKLTEMSLSANQERSTMEKKRLVWKVEGEG----------SYGEEKKAKRGREIDP 991

  Fly   989 -EFSVTLHPMQIRTFIIKTE 1007
             :..:.|:||:|||.:|..|
plant   992 RKLEMELYPMEIRTVLIHLE 1011

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
LManVI	NP_609253.1	GH38N_AMII_LAM_like	38..312	CDD:212121	127/277 (46%)
		Alpha-mann_mid	359..434	CDD:286360	32/74 (43%)
		Glyco_hydro_38C	482..1002	CDD:285047	178/563 (32%)
AT5G13980	NP_196902.2	PLN02701	36..820	CDD:178304	319/821 (39%)
AT5G13980	NP_196902.2	GH38N_AMII_LAM_like	37..313	CDD:212121	127/277 (46%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	310	1.000	Domainoid score	I311
eggNOG	1	0.900	-	-		E1_KOG1959
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	649	1.000	Inparanoid score	I170
OMA	1	1.010	-	-		QHG55625
OrthoDB	1	1.010	-	-		D201312at2759
OrthoFinder	1	1.000	-	-		FOG0001724
OrthoInspector	1	1.000	-	-		mtm1010
orthoMCL	1	0.900	-	-		OOG6_101099
Panther	1	1.100	-	-	O	PTHR11607
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X1279
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	14	13.840