DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment LManVI and AT3G26720

DIOPT Version :9

Sequence 1:	NP_609253.1	Gene:	LManVI / 34206	FlyBaseID:	FBgn0032069	Length:	1007	Species:	Drosophila melanogaster
Sequence 2:	NP_189306.1	Gene:	AT3G26720 / 822284	AraportID:	AT3G26720	Length:	1019	Species:	Arabidopsis thaliana

Alignment Length:	1060	Identity:	374/1060 - (35%)
Similarity:	571/1060 - (53%)	Gaps:	128/1060 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 LFVALLAISV-RPSEEACGYEACPKTKTNMINIHMVPHSHDDVGWLKTVDQYFYGHRSNIQHAGV 72
            |::.|.||.: ..:.|...|...|:.....||:|:|||||||||||||||||:.|..::|:.|.|
plant     8 LYLILAAIVIGGVTSEYIEYNTKPRIVPEKINVHLVPHSHDDVGWLKTVDQYYVGSNNSIRGACV 72

  Fly    73 QYIIDTVIAELIKDPARRFIQVETSFFAKWWAEQSETAKQVVRKLVNEGRLEFTGGAWSMNDEAA 137
            |.::|:|||.|:.|..|:||.||.:||.:||.:||...|..|:|||:.|:|||..|...|:|||.
plant    73 QNVLDSVIASLLDDENRKFIYVEMAFFQRWWRQQSNAKKVKVKKLVDSGQLEFINGGMCMHDEAT 137

  Fly   138 VNYQSVIDQFTLGLKFLDDTFGSCARPRIGWQIDPFGHSREQASIF-AQMGYDGEFFARMDHRDK 201
            .:|..:|||.|||.:|:...||..  ||:||||||||||..||.:. |:.|:|..||||:|::|:
plant   138 PHYIDMIDQTTLGHQFIKTEFGQV--PRVGWQIDPFGHSAVQAYLLGAEFGFDSLFFARIDYQDR 200

  Fly   202 NDRIDNLGMEMIWDASDSL-SNDEIFTGLLYRHYSAPPGYCFDVH-----CGDDPIIDTKSYDNN 260
            ..|:....:|:||..|.|| |:.:||||:..|||..|.|:.|:::     ..|||::    :|.|
plant   201 AKRLREKTLEVIWQGSKSLGSSSQIFTGVFPRHYDPPEGFTFEINDVSAPIQDDPLL----FDYN 261

  Fly   261 VKSRVDDFLSYVTSVAQHYRSNHIMIPMGDDFQYEDAQVNFKNMDKLIKYVNERQAEGSTFNLFY 325
            |:.||:||::...:.....|:||||..||.||:|:.|...|:.:||.|.|||    :....|:.|
plant   262 VQERVNDFVAAALAQVNVTRTNHIMWLMGTDFRYQYAYSWFRQIDKFIHYVN----KDGRLNVLY 322

  Fly   326 STPACYLNSLHEGLQTWPNKTQDFFPYGSDDNSYWTGYFTSRPTQKRFERDGNHILQVAKQLSVF 390
            |||:.|.::.:...::||.||.|||||....|:||||||||||..|::.||.:.....|:||...
plant   323 STPSIYTDAKYAANESWPLKTDDFFPYADKPNAYWTGYFTSRPAFKKYVRDLSGYYLAARQLEFL 387

  Fly   391 AELNTKQQKEDLEYLREIMGVMQHHDAITGTEKQHVSDDYD-RI---------LYDAILGGVNTA 445
            ...::.....|:  |.:.:.:.|||||::||::|||:.||. |:         |..:.|..::.|
plant   388 RGRDSSGPTTDM--LADALAIAQHHDAVSGTQRQHVAADYALRLSMGYLQAEKLVASSLSFLSAA 450

  Fly   446 RDGLRKLTNLPNGEFESCLQLNISECAFTKD---DADNVVVTLYNPLAHTSTQYVRVPVKNENYE 507
            :....|..  |..:|:.|..||||.|..::.   ...::||.:||.|.....:.|||||.:||..
plant   451 KSSTEKKN--PGTKFQQCPLLNISYCPASEARLLSGKSLVVVVYNSLGWKREEVVRVPVSSENVI 513

  Fly   508 VTDEKGRVVASEVVPVAWQVLALEFRN-----------NDT-QHELVFKASVDKI--ANYYIKKV 558
            |.|..|:.|..:::|::  .:||..||           .|| :|.|.|.|||..:  ::|.|...
plant   514 VKDASGKEVVFQLLPLS--EIALRIRNEYVKAYLGRSPRDTAKHVLAFTASVPPLGFSSYVISDT 576

  Fly   559 ASQETKNVAAHTKS---KRSIKAEEANLEVPKRFKKVHSLKNATETFDDDEGETVVQTSQVKLVI 620
            ........|::..|   .::::..:.||::  |:              .:||..:.:....|
plant   577 GRTARGLSASYVTSGSMNQNVEVGQGNLKL--RY--------------SEEGVKITRHLSTK--- 622

  Fly   621 DNKTGLLKTVEMNGVSENIDQSYGVY--------RTYDSGAYVFRQYHQADFIV---QYEGVEFT 674
                        |.|:  .:|||..|        ....|||||||    .|.::   ..|..:.|
plant   623 ------------NQVT--AEQSYAYYIGSNGTDKDPQASGAYVFR----PDGVLPIKSKEEAQLT 669

  Fly   675 VYDGALVKEVHQQFSEYISQVIRIYEGKNLVEIEWQVGPIEREEEFGREVVIIFNSTIASDGVSY 739
            :..|.|..||||:.:.:|||:.|:|:|||..|||:.:|||..::...:|::....:|:.::|..|
plant   670 IVQGPLFDEVHQELNSWISQITRVYKGKNHAEIEFTIGPIPADDGISKEIITKLTTTMKTNGTFY 734

  Fly   740 TDSNGREMIKRVKDQRETFTPGLDRQPTAANYYPVTSRIALQDSKKRIAVLNDRAQGGASMLNGQ 804
            ||||||:.|||::|.|..:...: .||.|.||||:...|.:||....::||.|||.||:|:.|||
plant   735 TDSNGRDFIKRIRDFRTDWDLQV-YQPVAGNYYPLNLGIYMQDKTSELSVLVDRAVGGSSLENGQ 798

  Fly   805 LELMLHRRLVRDDGYGVGEALNE----EKYGQPMIARGKVYLILSPSDESTAAEREAEKEIHLPF 865
            :|||||||:..||..||||.|||    .:..:.:..:||.|:.:....:.....|...:||:.|.
plant   799 IELMLHRRMQHDDIRGVGEILNETVCLPEGCKGLTIQGKFYVQIDKPGDGAKWRRTFGQEIYSPL 863

  Fly   866 WKFFSKNTGST------TAAAKSVPSFNDFPKSVHLLTLEPFNDDEVLLRVENFLDHTEGQ---- 920
            ...|::..|.:      |..:...||:: .||:|.||||:...:.|||||:.:..:..|..
plant   864 LIAFTEQEGDSWINSHKTTFSAFEPSYS-LPKNVALLTLQELENGEVLLRLAHLFEVGEDSEYSV 927

  Fly   921 VVSFNIRPIFDYLNGVEIRETTLDGNLPLSDMKRFKFHHDSSGQKPDAVEYFTSAHKPLAAEQSQ 985
            :....::.:|......|::||:|.||...::|::.:......|          ||.:.:...::.
plant   928 MAKVELKKLFHNKKIREVKETSLSGNQEKAEMEKRRLIWKVEG----------SAGEEVKRGEAV 982

  Fly   986 EASEFSVTLHPMQIRTFIIK 1005
            :|.:..|.|.||:|||.:||
plant   983 DAEKLVVELVPMEIRTLLIK 1002

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
LManVI	NP_609253.1	GH38N_AMII_LAM_like	38..312	CDD:212121	133/280 (48%)
		Alpha-mann_mid	359..434	CDD:286360	31/84 (37%)
		Glyco_hydro_38C	482..1002	CDD:285047	170/561 (30%)
AT3G26720	NP_189306.1	PLN02701	36..997	CDD:178304	362/1025 (35%)
AT3G26720	NP_189306.1	GH38N_AMII_LAM_like	38..314	CDD:212121	135/285 (47%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	310	1.000	Domainoid score	I311
eggNOG	1	0.900	-	-		E1_KOG1959
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	649	1.000	Inparanoid score	I170
OMA	1	1.010	-	-		QHG55625
OrthoDB	1	1.010	-	-		D201312at2759
OrthoFinder	1	1.000	-	-		FOG0001724
OrthoInspector	1	1.000	-	-		mtm1010
orthoMCL	1	0.900	-	-		OOG6_101099
Panther	1	1.100	-	-	O	PTHR11607
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X1279
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	13	12.840