Protein Alignment LManVI and Man2b2

DIOPT Version :9

• Sequence 1: NP_609253.1
• Gene: LManVI / 34206
• FlyBaseID: FBgn0032069
• Length: 1007
• Species: Drosophila melanogaster
• Sequence 2: NP_032576.2
• Gene: Man2b2 / 17160
• MGIID: 1195262
• Length: 1018
• Species: Mus musculus
• Alignment Length: 1094
• Identity: 300/1094 - (27%)
• Similarity: 460/1094 - (42%)
• Gaps: 231/1094 - (21%)

  Fly    38 INIHMVPHSHDDVGWLKTVDQYFYGHRSNIQHAGVQYIIDTVIAELIKDPARRFIQVETSFFAKW 102
            |...:|||||.||||:.||.:....:.:|        :..||:|||::...||||.||..||..|
Mouse    27 IRAFVVPHSHMDVGWVFTVQESMRAYAAN--------VYTTVVAELVRGGQRRFIAVEQEFFRLW 83

  Fly   103 W-AEQSETAKQVVRKLVNEGRLEFTGGAWSMNDEAAVNYQSVIDQFTLGLKFLDDTFGSCARPRI 166
            | ...||..||.||:|::||||||..|...|:|||..:....|.|.|.|..||.:|||  .||:.
Mouse    84 WDGVASEQQKQQVRQLLHEGRLEFVLGGQVMHDEAVTHLDDQILQLTEGHGFLYETFG--IRPQF 146

  Fly   167 GWQIDPFGHSREQASIFAQMGYDGEFFARMDHRDKNDRIDNLGM-EMIWDASDSLS-NDEIFTGL 229
            .|.:||||.|....::||..|::....:|:|: |..|.:....| :.:|..|.||| ..||||.:
Mouse   147 SWHVDPFGASATTPTLFALAGFNAHLISRIDY-DLKDAMQEAQMLQFVWHGSPSLSGQQEIFTHV 210

  Fly   230 LYRHYSAPPGYCFDVHC----------------------GDDPIIDTKSYDNNVKSRVDDFLSYV 272
            : .|||    ||...|.                      |..|.:.......|:....:..::.|
Mouse   211 M-DHYS----YCTPSHIPFSNRSGFYWNGVAVFPEPPPDGVYPNMSEPVTGANIHLYAEALVANV 270

  Fly   273 TSVAQHYRSNHIMIPMGDDFQYEDAQVNFKNMDKLIKYVNERQAEGSTFNLFYSTPACYLNSLHE 337
            ...|..:|:.|::.|.|.|.|:.:|.|.|.|||.|:.|:|:|.|:.. .::.|:|...|..:||.
Mouse   271 KQRAAWFRTPHVLWPWGCDKQFFNASVQFDNMDPLLDYINQRTAQFG-ISVQYATLNDYFQALHA 334

  Fly   338 GLQTWPNKT-QDFFPYGSDDNSYWTGYFTSRPTQKRFERDGNHILQVAKQLSVFAE--------- 392
            ...||..:. |||.||.|:....|||::|||.|.|...|..:.:|...:  |:|..
Mouse   335 TNMTWGIRDHQDFLPYSSEPLQAWTGFYTSRSTLKGLARQASALLYAGE--SMFTRYMWPDPSGT 397

  Fly   393 LNTKQQKEDLEYLREIMGVMQHHDAITGTEKQHVSDDYD-----------RILYDAILGGVNTAR 446
            |:.....:.|:.||..:..:||||||||||...|.:.|.           :::....|||...:.
Mouse   398 LDPTWALQQLQQLRWAVSEVQHHDAITGTESPKVKNMYTEHLRMGMLGVRKLMVSIALGGPPGSG 462

  Fly   447 DGLRKLTNLPNGEFESCLQLNISECAFTKDDADNVVVTLYNPLAHTSTQYVRVPVKNENYEVTDE 511
            .|..|  ::...:....|.::.....::        .::|||||...|..:.:.|...|..||||
Mouse   463 TGAPK--DIMGPQVTPVLSVDTRPVGYS--------ASVYNPLAWKITTIITLTVAFPNVSVTDE 517

  Fly   512 KGRVVASEVV-----PVAWQVL------ALEFRNNDTQHELVFKASVDKIANYYIKKVASQETKN 565
            .|..|::::.     |.|:.:|      .|.:|:....|
Mouse   518 LGHPVSTQIQNSTKDPSAYDLLILTTIPGLNYRHYQVMH-------------------------- 556

  Fly   566 VAAHTKSKRSIKAEEANLEVPKRFKKVHSLKNATETFDDDEGETVVQTSQVKLVIDNKTGLL--- 627
                   .|..:|....|..|:......|||...:...:.:....|......|:.|..|.:|
Mouse   557 -------ARGDQAGTRELVAPRANTLKFSLKLRNQPSQEGKRLVPVMNDCYILLFDQDTNMLHSI 614

  Fly   628 ------KTVEMNGVSENIDQSYGVYRTYDSGAYVFRQYHQADFIVQYEGVEFTVYDGALVKEVHQ 686
                  :||.|.........::.|.:...|..|:|...:.|:  ..:|.|...:..|.||.::.|
Mouse   615 QDRQSNRTVRMTQEFLEYQANWDVKQGPISDNYLFAPNNTAE--PSWEAVGMEMVAGTLVTDIRQ 677

  Fly   687 QFSEYISQVIRIYE-----------GKNL---VEIEWQVGPIEREEEFGREVVIIFNSTIASDGV 737
            .|..||:....||.           |:.|   :|.:::|||:    :..||.::..:|.:.|..|
Mouse   678 YFYRYITDQEYIYSIHTRLAHPSLAGELLCQRIEQQYRVGPL----DLNREAILRTSSDLNSQQV 738

  Fly   738 SYTDSNGREMIKRVKDQRETFTPGLDRQPTAANYYPVTSRIALQDSKKRIAVLNDRAQGGASMLN 802
            .|:|:||.:|      ||..: ......|...||||:.....::|.|.|:.:|.:|..|.:|..|
Mouse   739 LYSDNNGYQM------QRRPY-KAFKSNPIPRNYYPMVQSAFIEDDKSRLVLLAERPHGVSSQGN 796

  Fly   803 GQLELMLHRR----LVRDDGYGVGEALNEEKYGQPMIARGKVYLILSPSDESTAAE--------- 854
            ||:|:|||||    |..|..|.:  .||:.....|::     :|:|.|....||..
Mouse   797 GQVEVMLHRRLWNNLAWDLKYNL--TLNDTSIVHPVL-----WLMLGPKSTMTALHPRSGVALQH 854

  Fly   855 ---------REAEKEIHLPFWKFFSKNTGSTTAAAK------SVPSFNDFPKS--VHLLTLE--- 899
                     .:.|..:|.|      .|....|....      |||.:. :.:|  .||..|:
Mouse   855 GPVVLLKELADEETPVHGP------HNPWPVTLPPNLHLQILSVPGWT-YSRSHAQHLRNLQRGH 912

  Fly   900 ----PFNDDEVLLRVENFLDHTEGQVVSFNIRP----IFDYLNG----VEIRETTLDGNLPLSDM 952
                ..|...||||:.:..:..|..|:|   ||    :...|.|    |.:.|.:|.|...:..:
Mouse   913 PEKPQANLQRVLLRLRHLYEAGEDPVLS---RPATVDLKVVLRGLGSVVAVEERSLTGTWDVQML 974

  Fly   953 KRFKFHHDSSGQKPDAVE-YFTSAHKPLAAEQSQEASEFSVTLHPMQIRTFIIK 1005
            :|:   |.|:  |.|.:: :.||..:|....        .:|::|.:||||.||
Mouse   975 QRW---HWST--KTDHLKGHPTSPPRPPGGS--------IITVYPKEIRTFFIK 1015

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
LManVI	NP_609253.1	GH38N_AMII_LAM_like	38..312	CDD:212121	105/298 (35%)
		Alpha-mann_mid	359..434	CDD:286360	28/94 (30%)
		Glyco_hydro_38C	482..1002	CDD:285047	141/599 (24%)
Man2b2	NP_032576.2	GH38N_AMII_Epman_like	27..352	CDD:212122	120/341 (35%)
		Alpha-mann_mid	358..439	CDD:214875	28/82 (34%)
		Glyco_hydro_38C	491..1012	CDD:285047	141/596 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1959
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S7020
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11607
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.860