Protein Alignment LManVI and Man2a1

DIOPT Version :9

• Sequence 1: NP_609253.1
• Gene: LManVI / 34206
• FlyBaseID: FBgn0032069
• Length: 1007
• Species: Drosophila melanogaster
• Sequence 2: NP_032575.2
• Gene: Man2a1 / 17158
• MGIID: 104669
• Length: 1150
• Species: Mus musculus
• Alignment Length: 1091
• Identity: 272/1091 - (24%)
• Similarity: 458/1091 - (41%)
• Gaps: 232/1091 - (21%)

  Fly    38 INIHMVPHSHDDVGWLKTVDQYFYGHRSNIQHAGVQYIIDTVIAELIKDPARRFIQVETSFFAKW 102
            :.:.:|||||:|.|||||.:.||        ....|||.:.::.:|.:|.:|:|:..|.|:.|||
Mouse   165 LQVFVVPHSHNDPGWLKTFNDYF--------RDKTQYIFNNMVLKLKEDSSRKFMWSEISYLAKW 221

  Fly   103 WAEQSETAKQVVRKLVNEGRLEFTGGAWSMNDEAAVNYQSVIDQFTLGLKFLDDTFGSCARPRIG 167
            |.......|:.|:.|:..|:||...|.|.|.|||..:|.::|||...|.::|:...|  .:||.|
Mouse   222 WDIIDIPKKEAVKSLLQNGQLEIVTGGWVMPDEATPHYFALIDQLIEGHQWLEKNLG--VKPRSG 284

  Fly   168 WQIDPFGHSREQASIFAQMGYDGEFFARMDHRDKNDRIDNLGMEMIWDAS-DSLSNDEIFTGLLY 231
            |.|||||||...|.:..:.|:......|:.:..|.....:..:|..|..: |..|..:|...::
Mouse   285 WAIDPFGHSPTMAYLLKRAGFSHMLIQRVHYAIKKHFSLHKTLEFFWRQNWDLGSATDILCHMM- 348

  Fly   232 RHYSAPPGYCFDV-H-CGDDPII----DTKSY-----------------DNNVKSRVDDFLSYVT 273
                  |.|.:|: | ||.||.|    |.|..                 ..||:||....|....
Mouse   349 ------PFYSYDIPHTCGPDPKICCQFDFKRLPGGRYGCPWGVPPEAISPGNVQSRAQMLLDQYR 407

  Fly   274 SVAQHYRSNHIMIPMGDDF---QYEDAQVNFKNMDKLIKYVNERQAEGSTFNLFYSTPACYLNSL 335
            ..::.:|:..::.|:||||   :|.:..:..:|.::|..|:|.:  ......:.:.|.:.|.::|
Mouse   408 KKSKLFRTKVLLAPLGDDFRFSEYTEWDLQCRNYEQLFSYMNSQ--PHLKVKIQFGTLSDYFDAL 470

  Fly   336 HEGL--------QTWPNKTQDFFPYGSDDNSYWTGYFTSRPTQKRFERDGNHILQVAKQLSVFAE 392
            .:.:        ..:|..:.|||.|...|:.||:|||||||..||.:|.....::.|:   :..:
Mouse   471 EKAVAAEKKSSQSVFPALSGDFFTYADRDDHYWSGYFTSRPFYKRMDRIMESRIRAAE---ILYQ 532

  Fly   393 LNTKQQKE-------------DLEYLREIMGVMQHHDAITGTEKQHVSDDYDRILYDAILGGVNT 444
            |..||.::             .|...|..:|:.|||||||||.|..|..||...|:.::
Mouse   533 LALKQAQKYKINKFLSSPHYTTLTEARRNLGLFQHHDAITGTAKDWVVVDYGTRLFQSL------ 591

  Fly   445 ARDGLRKLTNLPNGEFESCLQLNISE---------CAFTKDDA---------DNVVVTL------ 485
              :.|.|:..      :|...|.:.:         .||.:.|.         ..:::.|
Mouse   592 --NSLEKIIG------DSAFLLILKDKKLYQSDPSKAFLEMDTKQSSQDSLPQKIIIQLSAQEPR 648

  Fly   486 ----YNPLAHTSTQYVRVPVKNENYEVTDEKGRVVASEVVPVAWQVLAL--EFRN-NDTQHELVF 543
                |||........|.:.|.:...:|..:.|:       ||..||.|:  :.|. :...:|:.|
Mouse   649 YLVVYNPFEQERHSVVSIRVNSATVKVLSDSGK-------PVEVQVSAVWNDMRTISQAAYEVSF 706

  Fly   544 KASVDKIANYYIKKVASQ-ETKNVAAHTKSKRSIKAEEANLEVPKRFKKVHSLKNATETFDDDEG 607
            .|.:..:.....|.:.|| .:.::|.:........||..          :..:||..     |.|
Mouse   707 LAHIPPLGLKVFKILESQSSSSHLADYVLYNNDGLAENG----------IFHVKNMV-----DAG 756

  Fly   608 ETVVQTSQVKLVIDNKTGLLKTVEMNGVSENIDQS-----YGVYRTYD-SGAYVFRQYHQADFIV 666
            :.:...:....:..:::||::.|.....|...:..     ||.....| ||||:|....|....|
Mouse   757 DAITIENPFLAIWFDRSGLMEKVRRKEDSRQHELKVQFLWYGTTNKRDKSGAYLFLPDGQGQPYV 821

  Fly   667 QYEGVEFTVYDGALVKEVHQQFSEYISQVIRIYEGKNLVEIEWQVGPIER----EEEFGREVVII 727
            ........|..|.:..:| ..|.|:::..:|:|   |:..||.|...:..    .....||:|:.
Mouse   822 SLRPPFVRVTRGRIYSDV-TCFLEHVTHKVRLY---NIQGIEGQSMEVSNIVNIRNVHNREIVMR 882

  Fly   728 FNSTIASDGVSYTDSNGREMIKRVKDQRETFTPGLDRQPTAANYYPVTSRIALQDSKKRIAVLND 792
            .:|.|.:....|||.||.::     ..|.|    :.:.|..||.||:.:...:||::.|:.:|:.
Mouse   883 ISSKINNQNRYYTDLNGYQI-----QPRRT----MSKLPLQANVYPMCTMAYIQDAEHRLTLLSA 938

  Fly   793 RAQGGASMLNGQLELMLHRRLVRDDGYGVGEALNEEKYGQPMIARGKVYLILSPSDESTAAEREA 857
            ::.|.:||.:||:|:.:.|||::||..|:|:.:::.|      ....::.||  .::.:|...|.
Mouse   939 QSLGASSMASGQIEVFMDRRLMQDDNRGLGQGVHDNK------ITANLFRIL--LEKRSAVNMEE 995

  Fly   858 EKEIHLPFWKFFSKNTGS---------TTAAAKSVPSF----------NDFPKSVHLLTL----- 898
            ||:..:.:....|..|.|         ..:.....|:|          :..|..:||:.|
Mouse   996 EKKSPVSYPSLLSHMTSSFLNHPFLPMVLSGQLPSPAFELLSEFPLLQSSLPCDIHLVNLRTIQS 1060

  Fly   899 ---EPFNDDEVLLRVENFLDHTEGQVVSFNIRPIFDYLNGVEIRETTLDGNLPLSDMKRF-KFHH 959
               :.::|:..|:.      |.:|....|:.|       |:.:..:|..|.  :|.:|.| ||
Mouse  1061 KMGKGYSDEAALIL------HRKGFDCQFSSR-------GIGLPCSTTQGK--MSVLKLFNKF-- 1108

  Fly   960 DSSGQKPDAVEYFTSA-----HKPLAAEQSQEASEFSVTLHPMQIRTFIIK 1005
                    |||....:     |.|..|:...|     |:|.||:|.||.|:
Mouse  1109 --------AVESLVPSSLSLMHSPPDAQNMSE-----VSLSPMEISTFRIR 1146

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
LManVI	NP_609253.1	GH38N_AMII_LAM_like	38..312	CDD:212121	91/300 (30%)
		Alpha-mann_mid	359..434	CDD:286360	32/87 (37%)
		Glyco_hydro_38C	482..1002	CDD:285047	128/576 (22%)
Man2a1	NP_032575.2	PLN02701	127..1148	CDD:178304	272/1091 (25%)
		GH38N_Man2A1	164..507	CDD:212131	104/360 (29%)
		Alpha-mann_mid	502..587	CDD:214875	32/87 (37%)
		Glyco_hydro_38C	757..1143	CDD:285047	101/436 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1959
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810