DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment LManV and AT5G66150

DIOPT Version :9

Sequence 1:	NP_001285763.1	Gene:	LManV / 34205	FlyBaseID:	FBgn0032068	Length:	982	Species:	Drosophila melanogaster
Sequence 2:	NP_201416.1	Gene:	AT5G66150 / 836747	AraportID:	AT5G66150	Length:	1047	Species:	Arabidopsis thaliana

Alignment Length:	1061	Identity:	353/1061 - (33%)
Similarity:	555/1061 - (52%)	Gaps:	113/1061 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MKFLGIVLCVAFLALQAKSAQAVCG-----YESCHETKSNMINIHLVPHSHDDVGWLKTVDQYYY 60
            |..|...|||....|.....::|.|     |.:..:.....:|:||||||||||||||||||||.
plant     6 MSLLKGSLCVIVFLLLLSLVESVKGGGYVKYGTEAKVVPGKLNVHLVPHSHDDVGWLKTVDQYYV 70

  Fly    61 GHRNNIQHAGVQYIIDTVISELIKNPDRRFIQVETSFFSKWWNEQSETMRAVVKMLVNEGRLQFI 125
            |..|.||:|.|:.::|:|:..|:::|:|:|:..|.:||::||.|||...:..|:.||..|:|:|:
plant    71 GSNNRIQNACVRNVLDSVVDSLLRDPNRKFVFAEMAFFTRWWEEQSPERQEQVRRLVKSGQLEFV 135

  Fly   126 NGAWSMNDEAAVNYQSVIDQFTVGLKFLDDTFGVCGRPRVGWQIDPFGHSREQASIY-AQMGFDG 189
            ||.|:|||||..:|..:|||.|.|.:|:...|..  .||..|||||||||..||.:. |::|.|.
plant   136 NGGWAMNDEATCHYIDMIDQTTKGHRFIKQQFNT--TPRAAWQIDPFGHSSVQAYLLGAELGLDS 198

  Fly   190 EFFSRMDHNDKGRRMNDLALEMIWDASESL-SQVKLFTGLLYTFYWDTPGFCFDVHCSDD--PII 251
            ..|:|:|:.|:.:|..:.:||:||..|::| |..::||.:.:..|....||.::|  :||  |:.
plant   199 VHFARIDYQDREKRKAEKSLEVIWRGSKTLDSSSQIFTNIFFVHYGPPTGFHYEV--TDDYVPLQ 261

  Fly   252 DSDSYDN-NVKSRVDDFIAYAAQVAEKFRTNHIMIPMGGDFQYEDAEVNYKNMDKLIKYVNERQS 315
            |:..:|. |:|..|:||:..:...|...|.||:|..||.||||:.||..::.||:||.|||:
plant   262 DNPRFDGYNIKEAVNDFVNASLVYANVSRGNHVMWTMGDDFQYQFAESWFRQMDRLIHYVNK--- 323

  Fly   316 SGSKYNIIYSTPTCYLNSVHKSVQSYPNKTLDFFPYGSDTNSFWTGYYTSRPTQKRFERDGNHIL 380
             ..:.|.:||||:.|:::.:.:..::|.||.|||||.....::||||:||||..||:.|..:...
plant   324 -DGRVNALYSTPSLYVDAKNVANVTWPLKTHDFFPYADRAYAYWTGYFTSRPALKRYVRALSGYY 387

  Fly   381 QVAKQLSAFAELSSTQQKEDLEYLREIMGVMQHHDAITGTEKQHVSDDYDRILYDAIVGGVKTAG 445
            ..|:||...  :.......:...|.:.:|:.|||||:|||.||||::||.:.|............
plant   388 MAARQLEFL--VGKNSGGPNTYSLGDALGIAQHHDAVTGTAKQHVTNDYMKRLALGASEAEAVVN 450

  Fly   446 DALRKLTN-LPNGE--------FESCLQLNISECAFTKD---GADNVVVTLYNALAHTTKQYVRV 498
            .||..|.| .|.|.        .:.|..:|||.|..|::   |..::::..||:|.....:.:|:
plant   451 SALACLMNKAPKGGCTKPAIAFSQQCSLMNISYCPSTEETLPGQKSLILVAYNSLGWNRTEIIRI 515

  Fly   499 PVKNENYQVTDEKGRVVASEIVPVPAEVLALEFRDSDT------------QHELVFKASVDKIA- 550
            ||.:....|.|..|..:.::.:|:  :.:....|...|            ::.|||||.|..:.
plant   516 PVNDAGLSVEDSSGNTLDAQYIPM--DNVTSNLRSFYTKAYLGISSLQRPKYWLVFKAKVPPLGW 578

  Fly   551 -NYYIKKVDSKESSNGVR--VISQPKANAETYDDEETIVQTSLIKLVLDNKTGLLKRV--EMNGV 610
             .::|.|..::.|:|...  |:..|..|.       |.:....:|:|..:.:|.|:|:  ...|.
plant   579 NTFFISKASAQGSNNHKHSSVMLSPMNNT-------TEIGPGNLKMVFSSDSGRLERMYNSRTGA 636

  Fly   611 SENIEQSYGLYRT--------YDSGAYVFRQYNQGDFVIQEDGV---------------EFTVYD 652
            ...::|:|..|.:        ..||||:||......:.:....:               :..:..
plant   637 DIKVDQNYFWYASNVGDAKDPQVSGAYIFRPNGSLAYPVSSSKICTVTSAFIGNGNVQSKLQIVR 701

  Fly   653 GALVKEVHQRFSEYISQVIRISEDKPYVEFEWLVGPIPVEEEF--GTEVVTIFSSEIASNGVFYT 715
            |.|:.||||:||.:::||:|:.::|.:.|||:.:|||.|.:..  |.|::|...:::.:...|||
plant   702 GPLIDEVHQQFSPWVAQVVRLYKEKEHAEFEFTIGPISVGKGHLTGKEIITRMVTDMTTAKEFYT 766

  Fly   716 DSNGRELIRREKDKREDFTPELAVQPTSGNYYPITSRIALQDSNKRLAILNDRAQGGTSMKDGQI 780
            |||||:.::|.:|.|.|:..|:. :|.:|||||:...:.::|....|::|.|||.||.|:|||:|
plant   767 DSNGRDFLKRVRDNRTDWHLEVN-EPIAGNYYPLNLGMYIKDEKAELSVLVDRATGGASIKDGEI 830

  Fly   781 ELMLHRRLVRDDGYGVGEAL------NEEKYGQPLIARGKVFLILNAADESTSAEREAEKEFHLP 839
            |||||||...||..||.|:|      |:...|  |..||..::.:|...|.....||..:|.:.|
plant   831 ELMLHRRTSMDDSRGVEESLVETVCVNDTCAG--LTIRGNYYVSINKVGEGGRWRRETGQEIYSP 893

  Fly   840 LWKFFS-----KNTGSTTAAAKSVPSFDDFPKSVHLLTLEPFNDDEILLRV----ENFKDHIEGK 895
            |...|:     |...|.|....::......|:::.|:|||..:...:|||:    |..:|....|
plant   894 LLMAFAHENKEKWKASNTVKGYAMDHLYTLPQNIALITLEELDLGNVLLRLAHLYEAGEDSDYSK 958

  Fly   896 VVSFNIRPIFDYLNGVEIRETTLDGNLPLSDMKQ-FKFHAEGSGIRGSEPEYYTSSHKPLSANQT 959
            :....::.:|......|:.|.:|..|.....||: .|:..||      |.|..:|   ||.....
plant   959 IAKVELKKLFSGKMIKEVTEMSLSANQEKVKMKEKMKWKVEG------EAEQPSS---PLRGGPV 1014

  Fly   960 QDAAEFAVTLYPMQIRTFIIK 980
             |.:...|.|.||:||||:::
plant  1015 -DKSTLVVELGPMEIRTFVVQ 1034

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
LManV	NP_001285763.1	GH38N_AMII_LAM_like	37..311	CDD:212121	125/278 (45%)
		Alpha-mann_mid	358..433	CDD:286360	30/74 (41%)
		Glyco_hydro_38C	481..977	CDD:285047	157/554 (28%)
AT5G66150	NP_201416.1	GH38N_AMII_LAM_like	47..323	CDD:212121	126/279 (45%)
		Alpha-mann_mid	365..438	CDD:214875	30/74 (41%)
		Glyco_hydro_38C	498..1031	CDD:285047	157/554 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	310	1.000	Domainoid score	I311
eggNOG	1	0.900	-	-		E1_KOG1959
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	649	1.000	Inparanoid score	I170
OMA	1	1.010	-	-		QHG55625
OrthoDB	1	1.010	-	-		D201312at2759
OrthoFinder	1	1.000	-	-		FOG0001724
OrthoInspector	1	1.000	-	-		mtm1010
orthoMCL	1	0.900	-	-		OOG6_101099
Panther	1	1.100	-	-	O	PTHR11607
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X1279
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	14	13.840