Protein Alignment LManV and man2b1

DIOPT Version :10

• Sequence 1: NP_609252.1
• Gene: LManV / 34205
• FlyBaseID: FBgn0032068
• Length: 982
• Species: Drosophila melanogaster
• Sequence 2: NP_001072469.1
• Gene: man2b1 / 779924
• XenbaseID: XB-GENE-958698
• Length: 995
• Species: Xenopus tropicalis
• Alignment Length: 1011
• Identity: 412/1011 - (40%)
• Similarity: 590/1011 - (58%)
• Gaps: 72/1011 - (7%)

  Fly     7 VLCVAFLALQA----KSAQAVCGYESCHETKSNMINIHLVPHSHDDVGWLKTVDQYYYGHRNNIQ 67
            :|.:..|.|.|    |.|:. ||.:||.:.....:|:||:||:|:||||||||||||||..|:||
 Frog     6 LLLLPLLLLGAAGRLKQAEG-CGEQSCPQAPDGFLNVHLIPHTHNDVGWLKTVDQYYYGAHNDIQ 69

  Fly    68 HAGVQYIIDTVISELIKNPDRRFIQVETSFFSKWWNEQSETMRAVVKMLVNEGRLQFINGAWSMN 132
            |||||||:|:|:|:|:.:|.:|||.||::||.:||.:|.|.:|..|..||.||||:||||.||||
 Frog    70 HAGVQYILDSVVSQLLHDPSKRFIYVESAFFWRWWKQQDELVRRDVTRLVEEGRLEFINGGWSMN 134

  Fly   133 DEAAVNYQSVIDQFTVGLKFLDDTFGVCGRPRVGWQIDPFGHSREQASIYAQMGFDGEFFSRMDH 197
            ||||.:|.|:|||.|:||:||..|||.||||||.|.|||||||||||.::||||:||.||.|:|:
 Frog   135 DEAATHYSSIIDQMTLGLQFLKSTFGDCGRPRVAWHIDPFGHSREQALLFAQMGYDGFFFGRLDY 199

  Fly   198 NDKGRRMNDLALEMIWDASESLS--QVKLFTGLLYTFYWDTPGFCFDVHCSDDPIIDSDSY-DNN 259
            .||..|.....:||:|.||:.:|  ...||||:|...|....|||:|..|.|.||||..|. |.|
 Frog   200 QDKANREKTKQMEMLWRASDDISPPYADLFTGVLPNGYNPPDGFCWDQLCDDTPIIDDPSVEDYN 264

  Fly   260 VKSRVDDFIAYAAQVAEKFRTNHIMIPMGGDFQYEDAEVNYKNMDKLIKYVNERQSSGSKYNIIY 324
            ....|..|:..|.|.|:|:.::||::.||.|||||:|.:.:||||:|||.||.:|.:|||.|:.|
 Frog   265 ADVIVQKFLKAATQQAQKYLSSHIVMTMGSDFQYENAIMWFKNMDRLIKNVNMQQINGSKVNVFY 329

  Fly   325 STPTCYLNSVHKSVQSYPNKTLDFFPYGSDTNSFWTGYYTSRPTQKRFERDGNHILQVAKQLSA- 388
            |||:|||.|:|::..::|.|..|||||....:.|||||:||||..|.:||..|:.|||..|:.|
 Frog   330 STPSCYLQSLHRANLTWPMKMDDFFPYADGPHMFWTGYFTSRPAFKGYERLSNNFLQVCNQMEAL 394

  Fly   389 ---------FAELSSTQQKEDLEYLREIMGVMQHHDAITGTEKQHVSDDYDRILYDAIVGGVKTA 444
                     :.:.|||       .:|..|||.|||||:|||.||||::||...|.:.........
 Frog   395 SGLEARNGPYGQSSST-------VMRRAMGVAQHHDAVTGTAKQHVNNDYSLRLSEGWDSCQVVI 452

  Fly   445 GDALRKLTNLPNGEFESCLQLNISECAFTKDGADNVVVTLYNALAHTTKQYVRVPVKNENYQVTD 509
            .::|..||.... .|..|..||||.|..| :.|:|..|.|||.|..:....||:||....|:|..
 Frog   453 SNSLSSLTGTKE-NFAFCNLLNISVCHVT-ETANNFKVYLYNPLGRSVTWTVRLPVNGHAYKVIG 515

  Fly   510 EKGRVVASEIVPVPAEVLALEFRDSDTQHELVFKASVDKI--ANYYIKKVDSKESSNGVRVISQP 572
            .....|.||:|.|.....||.|:....:.||:|:..:..:  :::.:.|:...:     |.:.:.
 Frog   516 PNDETVPSEVVDVSDFTKALRFQQGGAERELIFQGQIPAVGFSSFTVGKLSLPD-----RFVIKG 575

  Fly   573 KANAETYDDEETIVQTSLIKLVLDNKTGLLKRVE--MNGVSENIEQSYGLYR--------TYDSG 627
            |...:..|.    :|....::..|.:|||:..:.  ...:|..::||:..|.        :..||
 Frog   576 KRGKKQPDK----IQNQYYRVDFDPETGLISGIHNLEKKISLPLKQSFYWYNASVGNEESSQPSG 636

  Fly   628 AYVFRQYNQGDFVIQEDGVEFTVYDGALVKEVHQRFSEYISQVIRISEDKPYVEFEWLVGPIPVE 692
            ||:||. |..|.|.....|...:...:||:||||.||.:.|||:|:..|:.|:|.||.|||:|:.
 Frog   637 AYIFRP-NNSDSVPVSQHVRSYLVQNSLVQEVHQNFSSWCSQVVRLYRDQRYIELEWTVGPVPIG 700

  Fly   693 EEFGTEVVTIFSSEIASNGVFYTDSNGRELIRREKDKREDFTPELAVQPTSGNYYPITSRIALQD 757
            :|:|.||:::..:.:.::||||||||||::::|.:|.||.:... ..:|.:|||||:.|||.::.
 Frog   701 DEWGKEVISLIETNLKTDGVFYTDSNGRQILKRRRDSRETWKLN-QTEPIAGNYYPVNSRIYIKG 764

  Fly   758 SNKRLAILNDRAQGGTSMKDGQIELMLHRRLVRDDGYGVGEALNEE-KYGQPLIARGKVFLILNA 821
            .|.::.:|.||:|||:|::||.:|||:||||:|||..||||.|.|. ..|:.::.||:..|:|:.
 Frog   765 KNTQVTVLTDRSQGGSSIRDGSLELMVHRRLLRDDYRGVGEPLLENGLLGEGIVVRGRHLLLLDH 829

  Fly   822 ADESTSAEREAEKEFHLPLWKFFSKNTG-----STTAAAKSVPSFDDFPKSVHLLTLEPFNDDEI 881
            |||:....|....:.::......|...|     |.|...|......:.|::.||||......|:|
 Frog   830 ADEAADTHRTLALQQYMSPQVVLSSGDGIPYSQSGTPKRKFSALNGELPQNGHLLTFAMHAADKI 894

  Fly   882 LLRVENFKDHIEGK----VVSFNIRPIFDYLNGVEIRETTLDGNLPLSDMKQFKFHAEGSGIRGS 942
            |||:|:.....|.|    .::.|:..:|..::.....||||..|:..|.:|:.::..     |..
 Frog   895 LLRLEHPFQSQESKNNSQPITINLNTLFSSVSLSNFEETTLGANMEKSRLKRLQWRT-----RTG 954

  Fly   943 EPEYYTSSHKPLSANQTQDAAEFAVTLYPMQIRTFI 978
            .|....|...|:     .|.:.  :||.||:||||:
 Frog   955 SPLQMDSPRAPV-----VDPSN--ITLSPMEIRTFL 983

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
LManV	NP_609252.1	GH38N_AMII_LAM_like	37..311	CDD:212121	158/276 (57%)
		PLN02701	39..873	CDD:178304	370/864 (43%)
man2b1	NP_001072469.1	PLN02701	39..987	CDD:178304	402/977 (41%)
		GH38N_AMII_LAM_like	39..317	CDD:212121	159/277 (57%)