Protein Alignment LManV and man2b1

DIOPT Version :10

• Sequence 1: NP_609252.1
• Gene: LManV / 34205
• FlyBaseID: FBgn0032068
• Length: 982
• Species: Drosophila melanogaster
• Sequence 2: XP_005169420.1
• Gene: man2b1 / 541519
• ZFINID: ZDB-GENE-050327-52
• Length: 984
• Species: Danio rerio
• Alignment Length: 1031
• Identity: 420/1031 - (40%)
• Similarity: 595/1031 - (57%)
• Gaps: 119/1031 - (11%)

  Fly     6 IVLCVAFLALQAKSAQAVCGYESCHETKSNMINIHLVPHSHDDVGWLKTVDQYYYGHRNNIQHAG 70
            ::.|.:.:........::|||:||..||.:|:|:|||||:|||||||||||||:||.||||||||
Zfish    13 LLFCFSLVFSLPTGRNSICGYKSCPATKPSMLNVHLVPHTHDDVGWLKTVDQYFYGDRNNIQHAG 77

  Fly    71 VQYIIDTVISELIKNPDRRFIQVETSFFSKWWNEQSETMRAVVKMLVNEGRLQFINGAWSMNDEA 135
            ||||:|:||.:|.|:|.||||.|||:||.:||.:|::..|.:|..|||||||:||||.|.|:|||
Zfish    78 VQYILDSVIDQLQKDPARRFIYVETAFFYRWWRQQNQNTRRIVTQLVNEGRLEFINGGWCMSDEA 142

  Fly   136 AVNYQSVIDQFTVGLKFLDDTFGVCGRPRVGWQIDPFGHSREQASIYAQMGFDGEFFSRMDHNDK 200
            ..:|.:||||.|:||:||:||||.||||||.|.||||||:||.|||:||||:||.||.|:|:.||
Zfish   143 TTHYSAVIDQMTLGLRFLNDTFGECGRPRVAWHIDPFGHAREHASIFAQMGYDGFFFGRLDYQDK 207

  Fly   201 GRRMNDLALEMIWDASESLSQ--VKLFTGLLYTFYWDTPGFCFDVHCSDDPIIDS-DSYDNNVKS 262
            .|||....:||:|.|||||:.  ..||||:|...|....|||:|..|.|.||.|. |..|.||..
Zfish   208 DRRMKTKEMEMLWRASESLTPPIADLFTGVLPNGYNPPEGFCWDQSCDDAPIRDDPDLEDYNVDE 272

  Fly   263 RVDDFIAYAAQVAEKFRTNHIMIPMGGDFQYEDAEVNYKNMDKLIKYVNERQSSGSKYNIIYSTP 327
            .|..|:..:.:.|:.::||||::.||.|||||:|.:.||||||||||||..|:.|||.|::||||
Zfish   273 IVQKFLNASHKQADYYKTNHIIMTMGSDFQYENANLWYKNMDKLIKYVNALQAKGSKLNVLYSTP 337

  Fly   328 TCYLNSVHKSVQSYPNKTLDFFPYGSDTNSFWTGYYTSRPTQKRFERDGNHILQVAKQLSAFAEL 392
            :|||..::.:..::|.||.|||||..|.:.|||||:||||..|.:||..|..||...||......
Zfish   338 SCYLQELNLANFTWPMKTDDFFPYADDAHDFWTGYFTSRPALKLYERLSNSRLQTCNQLEVLGGP 402

  Fly   393 SSTQ---QKEDLEYLREIMGVMQHHDAITGTEKQHVSDDYDRIL------YDAIVG---GVKTAG 445
            :||.   .:.|.:.:|..|||.|||||::|||||||::||.|.|      .:.:|.   .|.:..
Zfish   403 TSTSGPFGEGDSDTMRRAMGVAQHHDAVSGTEKQHVANDYARRLATGWAHCEVLVSNSLAVLSGS 467

  Fly   446 DALRKLTNLPNGEFESCLQLNISECAFTKDGADNVVVTLYNALAHTTKQYVRVPVKNENYQVTDE 510
            :|.|..          |..||||.|..| :.:....:.:||.|..|.:..||:||....|.|||.
Zfish   468 EAPRVF----------CENLNISVCPLT-ESSHKFSMNVYNPLGRTVRWPVRLPVNGSVYNVTDA 521

  Fly   511 KGRVVASEIVPVPAEVLALEFRDSDTQHELVFKASVDKI--ANYYIKKVDSK----ESSNGVRVI 569
            .|:.|.||::|:......:.......:.||||:.....:  :.|.|..|..:    .|.|.|
Zfish   522 NGKAVDSEVIPLSKSRKEVRQNRGFAKSELVFQVEAPPLGYSTYIISMVQDQPPVSRSKNAV--- 583

  Fly   570 SQPKANAETYDDEETIVQTSLIKLVLDNKTGLLKRVEMNGVSENIE--QSYGLYRT--------- 623
              |.:           :|...:|:..|:.||||..:......:.|.  |::..|..
Zfish   584 --PSS-----------IQNKFLKVTFDSTTGLLSSLTNLETQQTIRLTQNFFWYNASAGNNKESH 635

  Fly   624 YDSGAYVFRQYNQGDFVIQEDG--VEFTVYDGALVKEVHQRFSEYISQVIRISEDKPYVEFEWLV 686
            ..||||:||..:...|:|.:..  ...::|:.  |:||.||||.::|||:|:.||:..:|.||.|
Zfish   636 QPSGAYIFRPNSSDPFIISKTAEIQAVSLYNS--VQEVTQRFSPWVSQVVRLYEDRRELELEWTV 698

  Fly   687 GPIPVEEEFGTEVVTIFSSEIASNGVFYTDSNGRELIRREKDKREDFTPELAVQPTSGNYYPITS 751
            ||:|||:..|.||:|...::|.|:|.|||||||||::.|.||.|..:..: ..:|.:||||||.|
Zfish   699 GPVPVEDGLGKEVITRLDTDIQSSGYFYTDSNGREVLERRKDYRPTWDLK-QTEPIAGNYYPINS 762

  Fly   752 RIALQDSNKRLAILNDRAQGGTSMKDGQIELMLHRRLVRDDGYGVGEALNEE-KYGQPLIARGKV 815
            |..::|..::|.::.||:||.:|:.:|.:|:||||||:.||..||||.|:|. ::...|:|||::
Zfish   763 RAYIKDDKRQLTVVTDRSQGASSIYNGSLEIMLHRRLLYDDFRGVGEPLSEPGEFAHGLVARGRL 827

  Fly   816 FLILNAADESTSAEREAEKEFHLPLWKFFSKNTGSTTAAAKSVPSFDD----------------- 863
            .|.|:..        ||..:.|.||         :.:...:.:.||.|
Zfish   828 LLTLSPP--------EAAADLHRPL---------AQSMVLQPLLSFQDGAPSPGTKLEFSGLQAA 875

  Fly   864 FPKSVHLLTLEPFNDDEILLRVENFKDHIEGKV----VSFNIRPIFDYLNGVEIRETTLDGNLPL 924
            .|.:|||||:..::.|.:|:|:|:.....|.|.    |:.|::.:|..|..:...|.:|..|...
Zfish   876 LPPAVHLLTVSQWDQDSVLVRLEHQYQAKESKTHSQPVTVNLQKLFSTLQVLGASEMSLGANQWK 940

  Fly   925 SDMKQFKFHAEGSGIRGSEPEYYTSSHKPLSANQTQDAAEFAVTLYPMQIRTFIIK 980
            .||.:..::.|...:             |.:|   :|.:.:.|||.||:||||:::
Zfish   941 EDMIRLHWNTEKDAL-------------PPTA---RDPSSWEVTLKPMEIRTFLLR 980

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
LManV	NP_609252.1	GH38N_AMII_LAM_like	37..311	CDD:212121	168/276 (61%)
		PLN02701	39..873	CDD:178304	381/885 (43%)
man2b1	XP_005169420.1	PLN02701	44..982	CDD:178304	411/1000 (41%)
		GH38N_AMII_LAM_like	44..322	CDD:212121	169/277 (61%)