Protein Alignment LManV and man2a2

DIOPT Version :10

• Sequence 1: NP_609252.1
• Gene: LManV / 34205
• FlyBaseID: FBgn0032068
• Length: 982
• Species: Drosophila melanogaster
• Sequence 2: NP_001006777.1
• Gene: man2a2 / 448465
• XenbaseID: XB-GENE-981388
• Length: 909
• Species: Xenopus tropicalis
• Alignment Length: 789
• Identity: 208/789 - (26%)
• Similarity: 352/789 - (44%)
• Gaps: 129/789 - (16%)

  Fly    25 GYESCHETK---SNMINIHLVPHSHDDVGWLKTVDQYYYGHRNNIQHAGVQYIIDTVISELIKNP 86
            |::..::.|   :..:.:.:|||||:|.||:||.|:|||..        .|:|::.::.:|.::|
 Frog   151 GFDITYDPKEWDNEPLQVFVVPHSHNDPGWIKTFDKYYYDQ--------TQHILNNMVVKLHEDP 207

  Fly    87 DRRFIQVETSFFSKWWNEQSETMRAVVKMLVNEGRLQFINGAWSMNDEAAVNYQSVIDQFTVG-- 149
            .|:||..|.|||||||:..:...||.|:.||..|:|:...|.|.|.|||..:|.::|||...|
 Frog   208 RRKFIWSEISFFSKWWDNINSQKRAAVRRLVASGQLEMTTGGWVMPDEANTHYFAMIDQMIEGHQ 272

  Fly   150 --LKFLDDTFGVCGRPRVGWQIDPFGHSREQASIYAQMGFDGEFFSRMDHNDKGRRMNDLALEMI 212
              .|.||.|      ||.||.:||||||.....|..:.........|:.::.|.......:||.:
 Frog   273 WLKKNLDAT------PRSGWAVDPFGHSSTMPYILRRSNLTSMLIQRVHYSIKKHFAATQSLEFM 331

  Fly   213 WDAS-ESLSQVKLFTGLLYTFYWDTPGFC---------FD--------VHC--SDDPIIDSDSYD 257
            |..: :..|...:|..::..:.:|.|..|         ||        ::|  ...|...:||
 Frog   332 WRQTWDPDSSTDIFCHMMPFYSYDVPHTCGPDPKICCQFDFRRLPGGRINCPWKVPPRAITDS-- 394

  Fly   258 NNVKSRVDDFIAYAAQVAEKFRTNHIMIPMGGDFQY---EDAEVNYKNMDKLIKYVNERQSSGSK 319
             ||..|.:..:....:.::.:|:..:::|:|.||:|   ::.:..:.|..||..|:|.......:
 Frog   395 -NVAERANILLDQYKKKSKLYRSKVVLVPLGDDFRYDKIQEWDAQFLNYQKLFDYMNSHPELHVQ 458

  Fly   320 YNIIYSTPTCYLNSVHKSV--------QSYPNKTLDFFPYGSDTNSFWTGYYTSRPTQKRFERDG 376
            ..  :.|.:.|.::::|.:        ..:|..:.|||.|....:.:|||||||||..|..:|..
 Frog   459 AQ--FGTLSDYFDALYKRMGVVPGIKPPDFPVVSGDFFSYADREDHYWTGYYTSRPFYKSMDRVL 521

  Fly   377 NHILQVAKQLSAF----AELSSTQQKEDL-EY-----LREIMGVMQHHDAITGTEKQHVSDDYDR 431
            ...|:.|:.|.:.    |..:.|:.|..| :|     .|..:|:.|||||||||.|:.|..||..
 Frog   522 ESHLRGAEILYSLAINHARKAGTESKYPLSDYALLTDARRNLGLFQHHDAITGTAKEAVVIDYGV 586

  Fly   432 ILYDAIVGGVKTAGDALRKLTNLPNGEF------------ESCL-QLNISECAFTKDGADNVVVT 483
            .|..:::...:...:|...|......::            ||.| |.::.|....|..|....|.
 Frog   587 RLLHSLMNLKRIIINAAHYLVVADKEKYHYDHSVPFFSTDESRLTQESLPEKTVIKLTASPRYVV 651

  Fly   484 LYNALAHTTKQYVRVPVKNENYQVTDEKGRVVASEIVPVPAEVLALEFRDSDTQHELVFKASVDK 548
            ::|.:.......|.:.|...|.:|..|.|:.||:::.||...|..:    :...:::.|.|.:..
 Frog   652 VFNPVEQNRLCVVSLLVNTYNVRVLTEDGQPVAAQLSPVWQSVTDM----NPDVYQVSFTARLPS 712

  Fly   549 IANYYIK---KVDSKES-SNGVRV------ISQPKAN------AETYDDEETIVQTSLIKLVLDN 597
            :.....:   .:|:..: .:.|||      :|..|.:      ||:..|:..| :...:::....
 Frog   713 LGLSIFQLHASIDTHTTLKSNVRVHLHGRELSIKKQDVFPVKVAESSTDDFHI-ENQYMQVWFSG 776

  Fly   598 KTGLLKRVEMNGVSENIEQS-------YGLYRTYD-SGAYVFRQYNQGDFVIQEDGVEFTVYDGA 654
            .|||||.::..|  |..||.       ||...:.| ||||:|....:......:|.....|.:|.
 Frog   777 TTGLLKSIKRAG--EEQEQKINMQFLIYGTRTSKDKSGAYLFLPDGEAKPYTPKDPPVVKVTEGP 839

  Fly   655 LVKEVHQRFSEYISQVIR---------ISEDKPYVEFEWLVGPIPVEEEFGTEVVTIFSSEIASN 710
            ...||..:: :::.||:|         :|.|        :...|.:.:....|:....|::|.|.
 Frog   840 FYSEVTCQY-QHVQQVMRLYNLPGTEGLSLD--------ISSLIDIRDHVNKEIAMRLSTDIQSE 895

  Fly   711 GVFYTDSNG 719
            .:|:||.||
 Frog   896 DIFFTDLNG 904

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
LManV	NP_609252.1	GH38N_AMII_LAM_like	37..311	CDD:212121	91/300 (30%)
		PLN02701	39..873	CDD:178304	206/772 (27%)
man2a2	NP_001006777.1	PLN02701	128..>906	CDD:178304	208/789 (26%)