Protein Alignment LManV and alpha-Man-IIb

DIOPT Version :10

• Sequence 1: NP_609252.1
• Gene: LManV / 34205
• FlyBaseID: FBgn0032068
• Length: 982
• Species: Drosophila melanogaster
• Sequence 2: NP_650494.2
• Gene: alpha-Man-IIb / 41913
• FlyBaseID: FBgn0026616
• Length: 1249
• Species: Drosophila melanogaster
• Alignment Length: 1162
• Identity: 280/1162 - (24%)
• Similarity: 461/1162 - (39%)
• Gaps: 309/1162 - (26%)

  Fly    37 INIHLVPHSHDDVGWLKTVDQYYYGHRNNIQHAGVQYIIDTVISELIKNPDRRFIQVETSFFSKW 101
            :.|.:|||||:|.|||||...|:        .:..:.|::.:::::.:..|..||..|.||...|
  Fly   168 LKIIVVPHSHNDPGWLKTFTNYF--------QSDSRQILNLLVTKMQEYTDMTFIWSEISFLQLW 224

  Fly   102 WNEQSETMRAVVKMLVNEGRLQFINGAWSMNDEAAVNYQSVIDQFTVGLKFLDDTFGVCGRPRVG 166
            |::...|.:..:|.|::.||::...|.|.|.|||.|:...::||...|.::|.:...|  .|:||
  Fly   225 WDQAHPTKQRALKRLIDAGRIEITTGGWVMTDEANVHIYPMLDQLIEGHQWLKNNLNV--TPKVG 287

  Fly   167 WQIDPFGHSREQASIYAQMGFDGEFFSRMDHNDKGRRMNDLALEMIWDASESLSQVKLFTGLLYT 231
            |.||||||......:.:...|:|....|:.:..|.......:.:.||..
  Fly   288 WSIDPFGHGSTVPYLLSGANFEGTIIQRIHYAWKQWFARQQSGDFIWKP---------------- 336

  Fly   232 FYWD-------------TPGFCFDVH-----CSDDPII-----------DSDSY--------DNN 259
             ||.             |....||::     |...|.|           :...|        |:|
  Fly   337 -YWRSRKDKDSEAGSLLTHNMPFDIYSIKGSCGPHPFICLNFDFRKIPGEYTEYSVKAQFITDDN 400

  Fly   260 VKSRVDDFIAYAAQVAEKFRTNHIMIPMGGDFQY-EDAEVN--YKNMDKLIKYV--NERQSSGSK 319
            ::|:....:...|:.|..|..|..:||:|.||:| :|.||:  |:|..|||.::  |.|     .
  Fly   401 LESKAQLLLEQYARTASLFPHNVALIPVGDDFRYNKDREVDQQYQNYKKLIDHIMANRR-----L 460

  Fly   320 YN--IIYSTPTCYLNSVHKSVQ----SYPNKTLDFFPYGSDTNS-----FWTGYYTSRPTQKRFE 373
            ||  |.:.||:.|..::.:.::    .:|....|||.| ||..|     :|:||:|:||..|...
  Fly   461 YNADIRFGTPSDYFEAIKERMKDHTPGFPTFKGDFFVY-SDIFSEGRPAYWSGYFTTRPFYKLLS 524

  Fly   374 RDGNHILQVAKQLSAFAELSSTQQKED------------LEYLREIMGVMQHHDAITGTEKQHVS 426
            .:..|.|:.|:.:...|..::.|.|.:            :...|..:|:.|||||||||.|..|.
  Fly   525 SELEHQLRSAEIVFTLAYNTARQAKRENAIKIYEKNYELIINARRNLGLFQHHDAITGTSKAAVM 589

  Fly   427 DDYDRILYDAIVGGVKTAGDALRKLTNLPNGEFESCLQLNISE----------CAFTKD------ 475
            .||...|:::....||..               ||||:|.:.:          ..|.:|
  Fly   590 RDYAMRLFESTQNMVKMQ---------------ESCLELLLQKGQPRHHGFLLSEFERDNFNKLP 639

  Fly   476 --------GADNVVVT---------------------LYNALAHTTKQYVRVPVKNENYQVTDEK 511
                    ..|....|                     |||:||....:.|.:.|::.|.::.::|
  Fly   640 RKMPIQMANGDESTPTVPAGEGGAGGSSSSGSVGSFVLYNSLAQKRLEVVTLRVQHPNVKIVNDK 704

  Fly   512 G-RVVASEIVPV-------------PAEVLALEFRDSDTQHELVFKASVDKIA-NYYIKKVDSKE 561
            | .:...:|.||             .........|.|..|.|::|.|.::.:: :.|..:||...
  Fly   705 GVELNHIQINPVWNITDTYEQGLGTSVSGTVGRIRTSTRQFEVMFVAELEPLSLSTYRVQVDEVN 769

  Fly   562 SSNGVRVI-------SQPKANA--ETYDDEETIV-------------QTSLIKLVLDNKTGLLKR 604
            ....:..|       |||.:.:  |..:...|.|             :...::|:.|.|:|.||.
  Fly   770 FKRNIATIYCDDCTESQPASVSPPEEIESSPTSVFEARGKPAGDIQLENPHMRLLFDEKSGFLKT 834

  Fly   605 VEMNGVSENIEQ------SYGLYRT--YDSGAYVFR---QYNQGDFVIQE--DGVEFTVYDGALV 656
            :......:.:.:      .:..||:  :.||||:|:   :.::.:..:.|  ..:...:..|.:.
  Fly   835 ITRKNQKKELLKPLQCNIKFAAYRSAQFHSGAYLFKTDPEQSEAEKEVLEGYTDMRIIITSGPIA 899

  Fly   657 KEVHQRFSEYISQVIRISEDKP------YVEFEWLVGPIPVEEEFGTEVVTIFSSEIASNG---- 711
            .:|...:..:::..:||...:.      |||.:....|.|...|  ||:...|.:.|.:..
  Fly   900 SDVTVIYGPFLAHTVRIFNTRTHLDAAIYVENDIDFEPPPKNRE--TELFMRFVTNIDNIAQAPM 962

  Fly   712 ------------------VFYTDSNGRELIRREKDKREDFTPELAVQPTSGNYYPITSRIALQDS 758
                              |||:|.||.:...|.|      .|.:.::   |||:||||...:|||
  Fly   963 QRDPLKEPVDAATMPELPVFYSDQNGFQYHERIK------VPAIGIE---GNYFPITSGAFIQDS 1018

  Fly   759 NKRLAILNDRAQGGTSMKDGQIELMLHRRLVRDDGYGVGEALNEEKYGQPLIARGKVFLILNAAD 823
            ..||.:|...|||..|.:.||:|:||.||.:.||..|:||.:.:.:     :.|.|.:|::....
  Fly  1019 RLRLTLLTTHAQGAASYEPGQLEVMLDRRTLYDDYRGMGEGVVDSR-----LTRHKFWLLVEDLP 1078

  Fly   824 E-------------STSAEREAEKEFHLPLWKFFSKNTGSTTAAAKSVPSFDDFPK-----SVHL 870
            .             |..|::.| .....|...:|..|......||..:|.....||     .|||
  Fly  1079 GGQHVTQPPSYKVLSQQAQQLA-NALRYPPNLYFVSNLEQPELAAALLPLVRLLPKGPLPCDVHL 1142

  Fly   871 LTLEPFNDDEILLRVENFKD-------HIEGKVVSFNIRPIFDYLNGVEIRETTLDGNLPLS--- 925
            .||...:|.|:.|    |..       |.:|...|.:..           ||.:::...|||
  Fly  1143 TTLRTLSDPELQL----FPSASALLVLHRQGFDCSVSAG-----------RELSMEAICPLSSKG 1192

  Fly   926 ----DMKQFKFHA-EGSGIRGSEPEYYTSSHKPLSANQTQDAAEFAVTLYPMQIRTF 977
                .:.:...|. |.:.:.|:|.:....|:      ..:..||  ::|.||::|||
  Fly  1193 LGNVQLGRLSLHTIEATSLTGTEQKSSRESY------HIRSLAE--ISLEPMELRTF 1241

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
LManV	NP_609252.1	GH38N_AMII_LAM_like	37..311	CDD:212121	85/315 (27%)
		PLN02701	39..873	CDD:178304	253/1039 (24%)
alpha-Man-IIb	NP_650494.2	PLN02701	148..1246	CDD:178304	280/1162 (24%)