Protein Alignment LManV and LManII

DIOPT Version :10

• Sequence 1: NP_609252.1
• Gene: LManV / 34205
• FlyBaseID: FBgn0032068
• Length: 982
• Species: Drosophila melanogaster
• Sequence 2: NP_609408.1
• Gene: LManII / 34437
• FlyBaseID: FBgn0027611
• Length: 1080
• Species: Drosophila melanogaster
• Alignment Length: 1083
• Identity: 483/1083 - (44%)
• Similarity: 671/1083 - (61%)
• Gaps: 129/1083 - (11%)

  Fly     4 LGIVLCVAFL-ALQAKSAQAVCGYESCHETKSNMINIHLVPHSHDDVGWLKTVDQYYYGHRNNIQ 67
            ||.::..|.| ::|.|::|  |||:|||.||.||:|:|||.|:||||||||||||||||....||
  Fly    15 LGCLIHDADLRSIQPKASQ--CGYQSCHPTKPNMLNVHLVAHTHDDVGWLKTVDQYYYGSETKIQ 77

  Fly    68 HAGVQYIIDTVISELIKNPDRRFIQVETSFFSKWWNEQSETMRAVVKMLVNEGRLQFINGAWSMN 132
            .||||||||:|:..|:::|::|||.||::||.|||.||...::..|||||.:|||:||.||||||
  Fly    78 KAGVQYIIDSVVEALLRDPEKRFIYVESAFFFKWWKEQKPKVQEAVKMLVEQGRLEFIGGAWSMN 142

  Fly   133 DEAAVNYQSVIDQFTVGLKFLDDTFGVCGRPRVGWQIDPFGHSREQASIYAQMGFDGEFFSRMDH 197
            |||..:||||||||:.||:.|:||||.||||||||||||||||||.||::|||||||.||.|:|:
  Fly   143 DEATTHYQSVIDQFSWGLRLLNDTFGECGRPRVGWQIDPFGHSREMASMFAQMGFDGMFFGRLDY 207

  Fly   198 NDKGRRMNDLALEMIWDASESL-SQVKLFTGLLYTFYWDTPGFCFDVHCSDDPIID-SDSYDNNV 260
            .||..|:.....||||..|.:| .:..||:|.||..|....|||||:.|:|.|||| ..|.||||
  Fly   208 QDKDERLMTKNAEMIWHGSANLGEEADLFSGALYNNYQAPDGFCFDILCNDAPIIDGKHSPDNNV 272

  Fly   261 KSRVDDFIAYAAQVAEKFRTNHIMIPMGGDFQYEDAEVNYKNMDKLIKYVNERQSSGSKYNIIYS 325
            |.|:|.|:.:|...::.:|||:|::.|||||.|:.|:|.|||:||||:|.||||::||..|::||
  Fly   273 KERIDTFLDFAKTQSQYYRTNNIIVTMGGDFTYQAAQVYYKNLDKLIRYGNERQANGSNINLLYS 337

  Fly   326 TPTCYLNSVHKSVQSYPNKTLDFFPYGSDTNSFWTGYYTSRPTQKRFERDGNHILQVAKQLSAFA 390
            ||:|||.|:|.:..::|.|:.|||||.||.:::||||:|||||.|||||||||.|||.|||||.|
  Fly   338 TPSCYLKSLHDAGITWPTKSDDFFPYASDPHAYWTGYFTSRPTLKRFERDGNHFLQVCKQLSALA 402

  Fly   391 ELSSTQQKEDLEYLREIMGVMQHHDAITGTEKQHVSDDYDRILYDAIVGGVKTAGDALRKLT--- 452
            .....:....|.::||.:|:||||||||||||:.|:.||.:.:..|......|..:||.:||
  Fly   403 PKKPEEFDPHLTFMRETLGIMQHHDAITGTEKEKVALDYAKRMSVAFRACGATTRNALNQLTVQS 467

  Fly   453 --NLPNG------EFESCLQLNISECAFTKDGADNVVVTLYNALAHTTKQYVRVPVKNENYQVTD 509
              |:.:.      ||::|..|||:.|. ..:..|...:||||.||||..:|||:||...||::.|
  Fly   468 KDNVKDTSAKYVFEFKTCALLNITSCP-VSEANDRFALTLYNPLAHTVNEYVRIPVPYSNYRIID 531

  Fly   510 EKGRVVASEIVPVPAEVLALEFRDSDTQHELVFKA-SVDKIA--NYYIKKVDSKESSNGVRVISQ 571
            .||..:.|:.||:|..::.::.|:|..::|:||.| ::..:.  .||::|:||.|.:...:.:
  Fly   532 NKGVTLESQAVPIPQVLIDIKHRNSTAKYEIVFLATNIPALGYRTYYVEKLDSTEGNTRSKAL-- 594

  Fly   572 PKANAETYDDEETIVQTSLIKLVLDNKTGLLKRVEMNGVSENIEQSYGLYR----------TYDS 626
            ||..:..     |::..|.|:|..|. .|.|..|..:|::..:.|.:..|.          ...|
  Fly   595 PKRTSSV-----TVIGNSHIQLGFDT-NGFLSEVTADGLTRLVSQEFLFYEGAVGNNAEFLNRSS 653

  Fly   627 GAYVFRQYNQGDFVIQEDGVEFTVYDGALVKEVHQRFSEYISQVIRISEDKPYVEFEWLVGPIPV 691
            |||:||. |:.......|.||..||.|.||.||||:|:::||||:|:.....|.||||||||||:
  Fly   654 GAYIFRP-NENKIHFATDQVEIEVYKGDLVHEVHQKFNDWISQVVRVYNKDSYAEFEWLVGPIPI 717

  Fly   692 EEEFGTEVVTIFSSEIASNGVFYTDSNGRELIRREKDKREDFTPELAVQPTSGNYYPITSRIALQ 756
            ::..|.||:|.|:|:|||:|:|.|||||||:|:|:.:.|:.::.::. :..:|||||||::|.::
  Fly   718 DDGIGKEVITRFNSDIASDGIFRTDSNGREMIKRKINHRDTWSVKIN-EAVAGNYYPITTKIDVE 781

  Fly   757 DSNKRLAILNDRAQGGTSMKDGQIELMLHRRLVRDDGYGVGEALNEEKYGQPLIARGKVFLILNA 821
            |...|:|||.||||||:|:|||.:|||:||||::||.:||||||||.:||..||||||..|....
  Fly   782 DDTARMAILTDRAQGGSSLKDGSLELMVHRRLLKDDAFGVGEALNETEYGDGLIARGKHHLFFGK 846

  Fly   822 ADESTSA-----EREAEKEFHLPLWKFFSKNTGSTTAAAKSVPSFDD--------FPKSVHLLTL 873
            :.:....     ||..:.|..||.|||||..  ...:|.:...:|.:        .||.||||||
  Fly   847 STDREGVSLKGIERLTQLEKLLPTWKFFSNM--EDYSADEWQTAFTNIFSGISLVLPKPVHLLTL 909

  Fly   874 EPFNDDEILLR----VENFKDHIEGKVVSFNIRPIFDYLNGVEIRETTLDGNLPLSDMKQFKF-- 932
            ||::::::|:|    :||.:|....:.|.||::.:....:...|||||||||..|.:.::.:|
  Fly   910 EPWHENQLLVRFEHIMENGEDASYSQPVQFNVKNVLSAFDVEGIRETTLDGNAWLDESRRLQFAP 974

  Fly   933 --------------------HA-----------------------------------------EG 936
                                |.                                         ||
  Fly   975 DPEEAAFNTYATFSQPAESVHLLSAEKPMLGVKYADEALPAGQLGAESNRIRRETETRQEKKDEG 1039

  Fly   937 SGIRGSEPEYYTSSHKPLSANQTQDAAEFAVTLYPMQIRTFII 979
            ...:.:|..|  :|.|..|:||     |:.:.|.||:|||||:
  Fly  1040 RSSKSTEGPY--NSFKSDSSNQ-----EYIIELSPMEIRTFIV 1075

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
LManV	NP_609252.1	GH38N_AMII_LAM_like	37..311	CDD:212121	167/275 (61%)
		PLN02701	39..873	CDD:178304	423/872 (49%)
LManII	NP_609408.1	PLN02701	47..823	CDD:178304	391/786 (50%)
		GH38N_AMII_LAM_like	47..323	CDD:212121	167/275 (61%)