Protein Alignment LManV and Man2b1

DIOPT Version :10

• Sequence 1: NP_609252.1
• Gene: LManV / 34205
• FlyBaseID: FBgn0032068
• Length: 982
• Species: Drosophila melanogaster
• Sequence 2: NP_001411770.1
• Gene: Man2b1 / 17159
• MGIID: 107286
• Length: 1024
• Species: Mus musculus
• Alignment Length: 1032
• Identity: 401/1032 - (38%)
• Similarity: 599/1032 - (58%)
• Gaps: 109/1032 - (10%)

  Fly     7 VLCVAF---LALQAKSAQAVCGYESCHETKSNMINIHLVPHSHDDVGWLKTVDQYYYGH------ 62
            ||.::|   |.|.|..|:| .||::|..||..|:|:||:||:||||||||||||||||.
Mouse    31 VLPISFLFWLLLAAPGARA-AGYKTCPPTKPGMLNVHLLPHTHDDVGWLKTVDQYYYGMDLDFLN 94

  Fly    63 -----RNNIQHAGVQYIIDTVISELIKNPDRRFIQVETSFFSKWWNEQSETMRAVVKMLVNEGRL 122
                 .:::|||.||||:|:|:|.|::.|.||||.||.:|||:||.:|:...:..|:.||.:|||
Mouse    95 FMPTVLSDVQHASVQYILDSVVSSLLEKPTRRFIYVEMAFFSRWWKQQTSATQDAVRNLVRQGRL 159

  Fly   123 QFINGAWSMNDEAAVNYQSVIDQFTVGLKFLDDTFGVCGRPRVGWQIDPFGHSREQASIYAQMGF 187
            :|:||.|.||||||.:|.:::||.|:||:||.||||..|.|||.|.||||||||||||::|||||
Mouse   160 EFVNGGWVMNDEAATHYGAIVDQMTLGLRFLQDTFGSDGLPRVAWHIDPFGHSREQASLFAQMGF 224

  Fly   188 DGEFFSRMDHNDKGRRMNDLALEMIWDASESLS--QVKLFTGLLYTFYWDTPGFCFDVHCSDDPI 250
            ||.|..|:|:.||..|...|.:|.:|.||:||.  ...||||:|...|......|:||.|:|.|:
Mouse   225 DGFFLGRIDYQDKLNRKKKLRMEELWRASDSLEPPAADLFTGVLPNNYNPPKYLCWDVLCTDPPV 289

  Fly   251 IDSD-SYDNNVKSRVDDFIAYAAQVAEKFRTNHIMIPMGGDFQYEDAEVNYKNMDKLIKYVNERQ 314
            :|:. |.:.|.|:.|:.|:..|:.....:||||.::.||.||.||:|.:.:|||||||:.||.:|
Mouse   290 VDNPRSPEFNAKTLVNYFLKLASSQKGFYRTNHTVMTMGSDFHYENANMWFKNMDKLIRLVNAQQ 354

  Fly   315 SSGSKYNIIYSTPTCYLNSVHKSVQSYPNKTLDFFPYGSDTNSFWTGYYTSRPTQKRFERDGNHI 379
            .:||..:::||||||||..::|:..::..|..|||||....:.|||||::|||..||:||...:.
Mouse   355 VNGSLVHVLYSTPTCYLWELNKANLTWTVKEDDFFPYADGPHMFWTGYFSSRPALKRYERLSYNF 419

  Fly   380 LQVAKQLSAFAELSST---QQKEDLEYLREIMGVMQHHDAITGTEKQHVSDDYDRILYDAIVGGV 441
            |||..||.|.....:.   ....|...|:|.|.|:|||||::||.:|:|.:||.|.|
Mouse   420 LQVCNQLEALVGPEANVGPYGSGDSAPLQEAMAVLQHHDAVSGTARQNVVNDYARQL-------- 476

  Fly   442 KTAG---------DALRKLTNLPNGEFESCLQLNISECAFTKDGADNVVVTLYNALAHTTKQYVR 497
             .||         :||.:|::... .|..|.:||||.|..::. ::...|||||.|.....|.||
Mouse   477 -AAGWGPCEVLVSNALARLSHYKQ-NFSFCRELNISICPVSQT-SERFQVTLYNPLGRKVDQMVR 538

  Fly   498 VPVKNENYQVTDEKGRVVASEIVPVPAEVLALEFRDSDTQHELVFKASVDKI--ANYYIKKVDSK 560
            :||...|:.|.|...:.::|.:|.||:      :.....|.||:|.|||..:  :.|.:.|: |.
Mouse   539 LPVYEGNFIVKDPHDKNISSNVVMVPS------YYSETYQWELLFPASVPALGFSTYSVAKM-SD 596

  Fly   561 ESSNGVRVISQPKANAETYDDEETIVQTSLIKLVLDNKTGLLKRVEMNGVSENIEQSYGL----- 620
            .:.....::|:|:.:...:   ..:::...::...|:.||||.::      ||:||:..|
Mouse   597 LNHQAHNLLSRPRKHKSHH---VLVIENKYMRATFDSGTGLLMKI------ENLEQNLSLPVSQG 652

  Fly   621 YRTYD-----------SGAYVFRQYNQGDFVIQEDGVEFTVYDGALVKEVHQRFSEYISQVIRIS 674
            :..|:           ||||:||. |.|..:......:.::...|||:||||.||.:.|||||:.
Mouse   653 FFWYNASVGDEESSQASGAYIFRP-NVGKPIPVSRWAQISLVKTALVQEVHQNFSAWCSQVIRLY 716

  Fly   675 EDKPYVEFEWLVGPIPVEEEFGTEVVTIFSSEIASNGVFYTDSNGRELIRREKDKREDFTPELAV 739
            :.:.::|.||.||||||.:::|.||::.|.:.:.:.|.|:|||||||:::|..|.|..:|.. ..
Mouse   717 KGQRHLELEWTVGPIPVRDDWGKEVISRFDTPMKTKGQFFTDSNGREILKRRDDYRPTWTLN-QT 780

  Fly   740 QPTSGNYYPITSRIALQDSNKRLAILNDRAQGGTSMKDGQIELMLHRRLVRDDGYGVGEALNEEK 804
            :|.:|||||:.:||.:.|...:|.:|.||:|||:|::||.:|||:||||:.||..||.|.|.|..
Mouse   781 EPVAGNYYPVNTRIYITDGQMQLTVLTDRSQGGSSLQDGSLELMVHRRLLVDDDRGVSEPLLETD 845

  Fly   805 YGQPLIARGKVFLILNAADESTSAER-EAEKEFHLPLWKFFSKNTGSTTAAAKSVPSF------D 862
            .|..:  ||:..::|::..::.:..| .||:|...|  :......||:...:::.|..      .
Mouse   846 TGDKV--RGRHLVLLSSVSDAAARHRLLAEQEVLAP--QVVLSLGGSSPYHSRATPKTQFSGLRQ 906

  Fly   863 DFPKSVHLLTLEPFNDDEILLRVEN---FKDHIEGKV---VSFNIRPIFDYLNGVEIRETTLDGN 921
            :.|..||||||..:....:|||:|:   .|:..:..:   |:.|::.:|.......::||||..|
Mouse   907 ELPPQVHLLTLARWGPKMLLLRLEHQFALKEDSDRNLSSPVTLNVQNLFQTFTINYLQETTLAAN 971

  Fly   922 LPLSDMKQFKFHAEGSGIRGSEPEYYTSSHKPLSANQTQDAAEFAVTLYPMQIRTFI 978
            .|||...:.|:      :..:.|   ||..:|...:.|      :|||.||:||||:
Mouse   972 QPLSRASRLKW------MTNTGP---TSYPEPSKLDPT------SVTLKPMEIRTFL 1013

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
LManV	NP_609252.1	GH38N_AMII_LAM_like	37..311	CDD:212121	147/287 (51%)
		PLN02701	39..873	CDD:178304	353/884 (40%)
Man2b1	NP_001411770.1	None