DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment LManIV and AT5G66150

DIOPT Version :9

Sequence 1:	NP_609251.2	Gene:	LManIV / 34204	FlyBaseID:	FBgn0032067	Length:	978	Species:	Drosophila melanogaster
Sequence 2:	NP_201416.1	Gene:	AT5G66150 / 836747	AraportID:	AT5G66150	Length:	1047	Species:	Arabidopsis thaliana

Alignment Length:	1072	Identity:	357/1072 - (33%)
Similarity:	555/1072 - (51%)	Gaps:	148/1072 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 GRILFLSILLVLFAKQSEAVCGYESCPETKANMV----NIHLVPHSHNDVGWLKTVDQSYYGYKN 65
            |.:..:..||:|...:|....||... .|:|.:|    |:|||||||:||||||||||.|.|..|
plant    11 GSLCVIVFLLLLSLVESVKGGGYVKY-GTEAKVVPGKLNVHLVPHSHDDVGWLKTVDQYYVGSNN 74

  Fly    66 KIHHAGVQYILDSVVSQLLQDPKRRFIQVETAFFAKWWNVQSESMKKVVTKLVNEGRFEFTGGAW 130
            :|.:|.|:.:|||||..||:||.|:|:..|.|||.:||..||...::.|.:||..|:.||..|.|
plant    75 RIQNACVRNVLDSVVDSLLRDPNRKFVFAEMAFFTRWWEEQSPERQEQVRRLVKSGQLEFVNGGW 139

  Fly   131 SMNDEANVNYQGVIDQFTVGLKFLNETFGSCGRPRVGWQIDTFGHSREQAAIF-AHMGYDGQFFS 194
            :|||||..:|..:|||.|.|.:|:.:.|.:  .||..||||.||||..||.:. |.:|.|...|:
plant   140 AMNDEATCHYIDMIDQTTKGHRFIKQQFNT--TPRAAWQIDPFGHSSVQAYLLGAELGLDSVHFA 202

  Fly   195 RMDHNDKDTRMNDLTMEMIWDASESM-SGVSLFSGMLYNFYSDTPGFCFDIL-----CTDQPIID 253
            |:|:.|::.|..:.::|:||..|::: |...:|:.:.:..|....||.:::.     ..|.|..|
plant   203 RIDYQDREKRKAEKSLEVIWRGSKTLDSSSQIFTNIFFVHYGPPTGFHYEVTDDYVPLQDNPRFD 267

  Fly   254 GDSEENNVKQRVDDFISYAKNVSEVYIT----NHIMVPMGGDFQYEDAKVNYKNMDKLIKYINER 314
            |    .|:|:.|:||:    |.|.||..    ||:|..||.||||:.|:..::.||:||.|:|:
plant   268 G----YNIKEAVNDFV----NASLVYANVSRGNHVMWTMGDDFQYQFAESWFRQMDRLIHYVNK- 323

  Fly   315 QASGSKYNIFYSTPSCYLNSLHQSLESWPNKTQDFFPYAHEKNSFWTGFFTSRPTQKRFERDGNH 379
               ..:.|..|||||.|:::.:.:..:||.||.||||||....::|||:|||||..||:.|..:.
plant   324 ---DGRVNALYSTPSLYVDAKNVANVTWPLKTHDFFPYADRAYAYWTGYFTSRPALKRYVRALSG 385

  Fly   380 MLQVAKQLSVLANLTSEEHKIDLDY-LRQVMGVMQHHDAITGTEKQAVSDDYDRMMYEAIVGASN 443
            ....|:||..|....|....   .| |...:|:.|||||:|||.||.|::||   |....:|||.
plant   386 YYMAARQLEFLVGKNSGGPN---TYSLGDALGIAQHHDAVTGTAKQHVTNDY---MKRLALGASE 444

  Fly   444 N---ARDALRLLTN-MPYGE--------FESCLRLNISECAFTKD---GADNVLVTLYNPLAHSS 493
            .   ...||..|.| .|.|.        .:.|..:|||.|..|::   |..::::..||.|..:.
plant   445 AEAVVNSALACLMNKAPKGGCTKPAIAFSQQCSLMNISYCPSTEETLPGQKSLILVAYNSLGWNR 509

  Fly   494 TQYVRIPVKEENYQVTDEKGRTVPSEVVPVPWQVLALEYRSNDT------------QHELVFKAT 546
            |:.:||||.:....|.|..|.|:.::.:|:  ..:....||..|            ::.|||||.
plant   510 TEIIRIPVNDAGLSVEDSSGNTLDAQYIPM--DNVTSNLRSFYTKAYLGISSLQRPKYWLVFKAK 572

  Fly   547 VNKV--SSYSIKKVE---SSEVKHSSIKKINPREDNNSETVVENSVVKLVMDNHTGRLKSV--EM 604
            |..:  :::.|.|..   |:..||||: .::|.   |:.|.:....:|:|..:.:|||:.:  ..
plant   573 VPPLGWNTFFISKASAQGSNNHKHSSV-MLSPM---NNTTEIGPGNLKMVFSSDSGRLERMYNSR 633

  Fly   605 NGVSEKIVQNFGVYKSH--------TSCAYTFRQDGDI--------------ELFEN---DFEFT 644
            .|...|:.||:..|.|:        .|.||.||.:|.:              ....|   ..:..
plant   634 TGADIKVDQNYFWYASNVGDAKDPQVSGAYIFRPNGSLAYPVSSSKICTVTSAFIGNGNVQSKLQ 698

  Fly   645 VYEGSLVKEVHQHVNDWISQVIRIYEGVSRVELEWMVGPIPI--DDKLGSEFVTNFKSEISSNGV 707
            :..|.|:.||||..:.|::||:|:|:.....|.|:.:|||.:  ....|.|.:|...:::::...
plant   699 IVRGPLIDEVHQQFSPWVAQVVRLYKEKEHAEFEFTIGPISVGKGHLTGKEIITRMVTDMTTAKE 763

  Fly   708 FYTDSNGRELMKRVKDKREDFVSDLSRQPVSGNFYPVTSRIALQDDTKRLVLLNDRSQGGASLED 772
            ||||||||:.:|||:|.|.|:..::: :|::||:||:...:.::|:...|.:|.||:.||||::|
plant   764 FYTDSNGRDFLKRVRDNRTDWHLEVN-EPIAGNYYPLNLGMYIKDEKAELSVLVDRATGGASIKD 827

  Fly   773 GALEMLIHRRHLFNDGGGVGEALNET----QYGKGLIARGKLYLILDSATDGDTVTERKTEKELF 833
            |.:|:::|||...:|..||.|:|.||    ....||..||..|:.::...:|.. ..|:|.:|::
plant   828 GEIELMLHRRTSMDDSRGVEESLVETVCVNDTCAGLTIRGNYYVSINKVGEGGR-WRRETGQEIY 891

  Fly   834 LPF-----------WKFFSKTGGVEITPSKSLPDFNDLPQSVHLLTLEFFSEQEILIRFEHFLDK 887
            .|.           ||..:...|.      ::.....|||::.|:|||......:|:|..|..:.
plant   892 SPLLMAFAHENKEKWKASNTVKGY------AMDHLYTLPQNIALITLEELDLGNVLLRLAHLYEA 950

  Fly   888 SE----GRVISFNIRDIFDSLGGLAIRETT---LDGNMPLSDMK-RFKFHAQESGTKPSSVEYST 944
            .|    .::....::.:|   .|..|:|.|   |..|.....|| :.|:..:....:|||
plant   951 GEDSDYSKIAKVELKKLF---SGKMIKEVTEMSLSANQEKVKMKEKMKWKVEGEAEQPSS----- 1007

  Fly   945 AQHKPLEAVKSDEASLFAVTLYPMQIRTFIIK 976
                ||.....|:::| .|.|.||:||||:::
plant  1008 ----PLRGGPVDKSTL-VVELGPMEIRTFVVQ 1034

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
LManIV	NP_609251.2	GH38N_AMII_LAM_like	39..312	CDD:212121	121/283 (43%)
		Alpha-mann_mid	359..434	CDD:214875	32/75 (43%)
		Glyco_hydro_38C	483..973	CDD:285047	157/558 (28%)
AT5G66150	NP_201416.1	GH38N_AMII_LAM_like	47..323	CDD:212121	121/285 (42%)
		Alpha-mann_mid	365..438	CDD:214875	33/78 (42%)
		Glyco_hydro_38C	498..1031	CDD:285047	157/559 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	310	1.000	Domainoid score	I311
eggNOG	1	0.900	-	-		E1_KOG1959
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	649	1.000	Inparanoid score	I170
OMA	1	1.010	-	-		QHG55625
OrthoDB	1	1.010	-	-		D201312at2759
OrthoFinder	1	1.000	-	-		FOG0001724
OrthoInspector	1	1.000	-	-		mtm1010
orthoMCL	1	0.900	-	-		OOG6_101099
Panther	1	1.100	-	-	O	PTHR11607
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X1279
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	14	13.840