Protein Alignment LManIV and alpha-Man-IIb

DIOPT Version :9

• Sequence 1: NP_609251.2
• Gene: LManIV / 34204
• FlyBaseID: FBgn0032067
• Length: 978
• Species: Drosophila melanogaster
• Sequence 2: NP_001262614.1
• Gene: alpha-Man-IIb / 41913
• FlyBaseID: FBgn0026616
• Length: 1249
• Species: Drosophila melanogaster
• Alignment Length: 1129
• Identity: 286/1129 - (25%)
• Similarity: 481/1129 - (42%)
• Gaps: 248/1129 - (21%)

  Fly    38 VNIHLVPHSHNDVGWLKTVDQSYYGYKNKIHHAGVQYILDSVVSQLLQDPKRRFIQVETAFFAKW 102
            :.|.:|||||||.|||||. .:|:       .:..:.||:.:|:::.:.....||..|.:|...|
  Fly   168 LKIIVVPHSHNDPGWLKTF-TNYF-------QSDSRQILNLLVTKMQEYTDMTFIWSEISFLQLW 224

  Fly   103 WNVQSESMKKVVTKLVNEGRFEFTGGAWSMNDEANVNYQGVIDQFTVGLKFLNETFGSCGRPRVG 167
            |:....:.::.:.:|::.||.|.|.|.|.|.|||||:...::||...|.::|......  .|:||
  Fly   225 WDQAHPTKQRALKRLIDAGRIEITTGGWVMTDEANVHIYPMLDQLIEGHQWLKNNLNV--TPKVG 287

  Fly   168 WQIDTFGHSREQAAIFAHMGYDGQFFSRMDHNDKDTRMNDLTMEMIWDA-------SESMSGVSL 225
            |.||.|||......:.:...::|....|:.:..|.......:.:.||..       .:|.:|..|
  Fly   288 WSIDPFGHGSTVPYLLSGANFEGTIIQRIHYAWKQWFARQQSGDFIWKPYWRSRKDKDSEAGSLL 352

  Fly   226 FSGMLYNFYSDTPGFC----FDILCTDQPIIDGDSEENNVKQR--VDDFI---------SYAKNV 275
            ...|.::.|| ..|.|    |..|..|...|.|:..|.:||.:  .||.:         .||:..
  Fly   353 THNMPFDIYS-IKGSCGPHPFICLNFDFRKIPGEYTEYSVKAQFITDDNLESKAQLLLEQYARTA 416

  Fly   276 SEVYITNHIMVPMGGDFQY-EDAKVN--YKNMDKLIKYINERQASGSKYN--IFYSTPSCYLNSL 335
            | ::..|..::|:|.||:| :|.:|:  |:|..|||.:|   .|:...||  |.:.|||.|..::
  Fly   417 S-LFPHNVALIPVGDDFRYNKDREVDQQYQNYKKLIDHI---MANRRLYNADIRFGTPSDYFEAI 477

  Fly   336 HQSLE----SWPNKTQDFFPY----AHEKNSFWTGFFTSRPTQKRFERDGNHMLQVAKQLSVLAN 392
            .:.::    .:|....|||.|    :..:.::|:|:||:||..|....:..|.|:.|:.:..||.
  Fly   478 KERMKDHTPGFPTFKGDFFVYSDIFSEGRPAYWSGYFTTRPFYKLLSSELEHQLRSAEIVFTLAY 542

  Fly   393 LTSEEHK-------IDLDY-----LRQVMGVMQHHDAITGTEKQAVSDDYDRMMYEAIVGASNNA 445
            .|:.:.|       .:.:|     .|:.:|:.|||||||||.|.||..||...::|:........
  Fly   543 NTARQAKRENAIKIYEKNYELIINARRNLGLFQHHDAITGTSKAAVMRDYAMRLFESTQNMVKMQ 607

  Fly   446 RDALRLL--TNMP------YGEFESCLRLNISEC--------------------------AFTKD 476
            ...|.||  ...|      ..|||   |.|.::.                          ..:..
  Fly   608 ESCLELLLQKGQPRHHGFLLSEFE---RDNFNKLPRKMPIQMANGDESTPTVPAGEGGAGGSSSS 669

  Fly   477 GADNVLVTLYNPLAHSSTQYVRIPVKEENYQVTDEKGRTVPS-EVVPVPWQVLAL---------- 530
            |:....| |||.||....:.|.:.|:..|.::.::||..:.. ::.|| |.:...
  Fly   670 GSVGSFV-LYNSLAQKRLEVVTLRVQHPNVKIVNDKGVELNHIQINPV-WNITDTYEQGLGTSVS 732

  Fly   531 ----EYRSNDTQHELVFKATVNKVSSYSIKKVESSEVK--------------HSSIKKINPRED- 576
                ..|::..|.|::|.|.:..: |.|..:|:..||.              .|....::|.|:
  Fly   733 GTVGRIRTSTRQFEVMFVAELEPL-SLSTYRVQVDEVNFKRNIATIYCDDCTESQPASVSPPEEI 796

  Fly   577 NNSETVV-------------ENSVVKLVMDNHTGRLKSVEMNGVSEKIVQ------NFGVYKS-- 620
            .:|.|.|             ||..::|:.|..:|.||::......:::::      .|..|:|
  Fly   797 ESSPTSVFEARGKPAGDIQLENPHMRLLFDEKSGFLKTITRKNQKKELLKPLQCNIKFAAYRSAQ 861

  Fly   621 -HTSCAYTFRQD-----GDIELFE--NDFEFTVYEGSLVKEVHQHVNDWISQVIRIYEGVSRV-- 675
             | |.||.|:.|     .:.|:.|  .|....:..|.:..:|......:::..:||:...:.:
  Fly   862 FH-SGAYLFKTDPEQSEAEKEVLEGYTDMRIIITSGPIASDVTVIYGPFLAHTVRIFNTRTHLDA 925

  Fly   676 ------ELEWMVGPIPIDDKLGSEFVTN-------------FKSEISSN-----GVFYTDSNGRE 716
                  ::::...|...:.:|...||||             .|..:.:.     .|||:|.||.:
  Fly   926 AIYVENDIDFEPPPKNRETELFMRFVTNIDNIAQAPMQRDPLKEPVDAATMPELPVFYSDQNGFQ 990

  Fly   717 LMKRVKDKREDFVSDLSRQPVSGNFYPVTSRIALQDDTKRLVLLNDRSQGGASLEDGALEMLIHR 781
            ..:|:|         :....:.||::|:||...:||...||.||...:||.||.|.|.||:::.|
  Fly   991 YHERIK---------VPAIGIEGNYFPITSGAFIQDSRLRLTLLTTHAQGAASYEPGQLEVMLDR 1046

  Fly   782 RHLFNDGGGVGEALNETQYGKGLIARGKLYLILDSATDGDTVTERKTEKEL------------FL 834
            |.|::|..|:||.:.:::     :.|.|.:|:::....|..||:..:.|.|            :.
  Fly  1047 RTLYDDYRGMGEGVVDSR-----LTRHKFWLLVEDLPGGQHVTQPPSYKVLSQQAQQLANALRYP 1106

  Fly   835 PFWKFFSKTGGVEITPS-----KSLPDFNDLPQSVHLLTLEFFSEQEILIRFEHFLDKSEGRVIS 894
            |...|.|.....|:..:     :.||. ..||..|||.||...|:.|:.:    |...|...|:.
  Fly  1107 PNLYFVSNLEQPELAAALLPLVRLLPK-GPLPCDVHLTTLRTLSDPELQL----FPSASALLVLH 1166

  Fly   895 FNIRDIFD---SLGGLAIRETTLDGNMPLS-------DMKRFKFHAQESGTKPSSVEYSTAQHKP 949
               |..||   |.|    ||.:::...|||       .:.|...|..|:.:...:.:.|:.:...
  Fly  1167 ---RQGFDCSVSAG----RELSMEAICPLSSKGLGNVQLGRLSLHTIEATSLTGTEQKSSRESYH 1224

  Fly   950 LEAVKSDEASLFAVTLYPMQIRTF 973
            :.       ||..::|.||::|||
  Fly  1225 IR-------SLAEISLEPMELRTF 1241

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
LManIV	NP_609251.2	GH38N_AMII_LAM_like	39..312	CDD:212121	88/297 (30%)
		Alpha-mann_mid	359..434	CDD:214875	31/86 (36%)
		Glyco_hydro_38C	483..973	CDD:285047	140/601 (23%)
alpha-Man-IIb	NP_001262614.1	PLN02701	148..1246	CDD:178304	286/1129 (25%)
		GH38N_AMII_GMII_SfManIII_like	167..514	CDD:212120	104/360 (29%)
		Alpha-mann_mid	508..596	CDD:286360	31/87 (36%)
		Glyco_hydro_38C	813..1241	CDD:285047	110/461 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45450133
Domainoid	1	1.000	50	1.000	Domainoid score	I680
eggNOG	1	0.900	-	-		E1_KOG1959
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	49	1.000	Inparanoid score	I462
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	5	4.790