Protein Alignment LManIV and aman-1

DIOPT Version :9

• Sequence 1: NP_609251.2
• Gene: LManIV / 34204
• FlyBaseID: FBgn0032067
• Length: 978
• Species: Drosophila melanogaster
• Sequence 2: NP_508811.1
• Gene: aman-1 / 180749
• WormBaseID: WBGene00018877
• Length: 955
• Species: Caenorhabditis elegans
• Alignment Length: 980
• Identity: 330/980 - (33%)
• Similarity: 524/980 - (53%)
• Gaps: 86/980 - (8%)

  Fly     6 RILFLSI-LLVLFAKQSEAVCGYESC--PETKANMVNIHLVPHSHNDVGWLKTVDQSYYGYKNKI 67
            :::||.: |||:::.|.   |.:.:|  .:...|::..||:||:|:|:||:|||||.::|.|.::
 Worm     4 QVIFLFLGLLVIYSSQD---CAWNTCHKVDQDPNVITAHLIPHTHDDLGWIKTVDQYFWGAKPEL 65

  Fly    68 HHAGVQYILDSVVSQLLQDPKRRFIQVETAFFAKWWNVQSESMKKVVTKLVNEGRFEFTGGAWSM 132
            ...|||||.::|:.:||::|.|||...||.|..:|:...|:..:..:.|||..|:.|..||.|..
 Worm    66 VPVGVQYIYNTVIDELLKNPDRRFSFAETGFLWRWYTSNSDFDRHQLQKLVKNGQIEIIGGGWVQ 130

  Fly   133 NDEANVNYQGVIDQFTVGLKFLNETFGSCGRPRVGWQIDTFGHSREQAAIFAHMGYDGQFFSRMD 197
            ||||..:|..:|||.|:||:.|.:.||.||:|..|||||.||||||.|.|:..|||...:|:|:.
 Worm   131 NDEATSHYVDIIDQMTLGLQRLEQIFGECGKPVTGWQIDPFGHSREMANIYREMGYSSVYFARIH 195

  Fly   198 HNDKDTRMNDLTMEMIWDASESMSGVSLFSGMLYN-FYSDTPGFCFDILCTDQPIIDG-DSEENN 260
            :.:|..|:.:.|:|.:|:.|:.::...||:|..:| .|....|||:|.||.|.||:|. :.|..|
 Worm   196 YLEKQIRLKNKTLEFMWNTSDDITDNKLFTGAFFNDNYGPPEGFCWDSLCGDDPIMDNLNIEGYN 260

  Fly   261 VKQRVDDFISYAKNVSEVYITNHIMVPMGGDFQYEDAKVNYKNMDKLIKYINERQASGSKYNIFY 325
            ||::||.|:.:.||.:....||.:|:.||.||||.:|...|.|:||||||:|  ..:..|..:.|
 Worm   261 VKEKVDAFVDHVKNQAAHQSTNQVMLLMGSDFQYTNANSWYVNLDKLIKYVN--ADTSKKVRVIY 323

  Fly   326 STPSCYLNSLHQSLESWPNKTQDFFPYAHEKNSFWTGFFTSRPTQKRFERDGNHMLQVAKQLSVL 390
            |||:||..::.....:...|..||||||..::|:|||:|||||..|...|..:.|||:||||.|:
 Worm   324 STPACYTKAVQAKTPTLSVKHDDFFPYASGRHSYWTGYFTSRPAFKGMIRQASCMLQLAKQLDVI 388

  Fly   391 ANLTSEEHKIDLDYLRQVMGVMQHHDAITGTEKQAVSDDYDRMMYEAIVGASNNARDALRLLTNM 455
            |||..|:.. |::.||:...::|||||:|||.|:.|:.||::.:.:.:........|.::.:.
 Worm   389 ANLGPEDDS-DIEILREASALVQHHDAVTGTAKENVTRDYEKQLAKGVSEVEVVINDFMKKMN-- 450

  Fly   456 PYG---EFESCLRLNISECAFTKDGADNVLVTLYNPLAHSSTQYVRIPVKEENYQVTDEKGRTVP 517
            |.|   :...|..:|.:.|. ..:|:....|.::|.........:|||..::...:.|.....:.
 Worm   451 PDGLDPKLVLCPLINETICK-PINGSSEFSVVIFNSNGRYFNGTIRIPYSQKTAVLRDAHKNVLE 514

  Fly   518 SEVVPVPWQVLALEYRSNDTQ------HELVFKATVNKVSSYSIKKVESSEVKHSSIKKINPRED 576
            |::|.. :|:..|:    ||.      |..|....:...:.:..|..:...|..::.||.|...:
 Worm   515 SQIVET-FQIDQLK----DTDRLPYEIHVFVRVPPLGYTTVFVEKGSKPERVHFNNRKKFNTNVE 574

  Fly   577 NNSETVV----ENSVVKLVMDNHTGRLKSVEM-----NGVSEKIVQNFGVY----KSHTSCAYTF 628
            ..:|.::    ....:..:.:..|.:.:|:..     .|:..|..|..|.|    |:....|.|
 Worm   575 IQNEYLIAGFDSQGYLSYITEKATKKKRSIRQEFFYYEGIDSKDDQPSGAYIFRPKTQQPIALT- 638

  Fly   629 RQDGDIELFENDFEFTVYEGSLVKEVHQHVNDWISQVIRIYEGVSRVELEWMVGPIPIDDK--LG 691
                      :.....|..|:::.||.|.|:.::||.||:..|.:.:|.||:|||||.:.|  :.
 Worm   639 ----------SKLALEVVPGAIINEVRQKVSPFVSQQIRLPRGKNYIEFEWIVGPIPKETKNPIT 693

  Fly   692 SEFVTNFKSEISSNGVFYTDSNGRELMKRVKDKREDF-VSDLSRQPVSGNFYPVTSRIALQDDTK 755
            .||||.:.:|:.|....:||||||:.|:|..|....| .||  .:|::||:||:||...::|:..
 Worm   694 KEFVTRYTTEVHSKNQSFTDSNGRQAMERFFDGATSFEYSD--TEPIAGNYYPITSFGYIKDENA 756

  Fly   756 RLVLLNDRSQGGASLEDGALEMLIHRRHLFNDGGGVGEALNET-QYGKGLIARGKLYLILDSATD 819
            :..::.||:||..: .||.:|:::|||..::|..||.|||:|. :.|.||:|.|| :::|.:...
 Worm   757 QFSVITDRAQGMVA-SDGVVEIMLHRRCFYDDHFGVEEALDEPGKDGAGLVAMGK-HIVLFTDVK 819

  Fly   820 GDTVTERKTEKELFLPFWKFFSKTGGVEITPSKSLPDFN----------DLPQSVHLLTLEFFSE 874
            ..|...|....:.|......|:|      .|.|.  :||          :||..:||||||.:.:
 Worm   820 ASTSQLRPLAIDNFHQPVLAFNK------NPEKF--EFNRLLEYSGLKFELPIGIHLLTLEKWHK 876

  Fly   875 QEILIRFEHFLDKSEGRVI-SFNIRDIFDSLGGLAIRETTLDGNMPLSDMKRFKFHAQESGTKPS 938
            :..|||||:.....||..| .|:...||.:...::.:|..|..|..:...|       |||:...
 Worm   877 KSSLIRFENIYHGEEGNSIKEFDPTHIFTNFDIVSFKELLLGANRVVGKNK-------ESGSSFR 934

  Fly   939 SVEYS 943
            |.|.|
 Worm   935 SFEKS 939

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
LManIV	NP_609251.2	GH38N_AMII_LAM_like	39..312	CDD:212121	123/274 (45%)
		Alpha-mann_mid	359..434	CDD:214875	37/74 (50%)
		Glyco_hydro_38C	483..973	CDD:285047	138/495 (28%)
aman-1	NP_508811.1	GH38N_AMII_LAM_like	36..313	CDD:212121	124/278 (45%)
		Alpha-mann_mid	357..431	CDD:286360	37/74 (50%)
		Glyco_hydro_38C	537..944	CDD:285047	126/433 (29%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160159879
Domainoid	1	1.000	326	1.000	Domainoid score	I640
eggNOG	1	0.900	-	-		E1_KOG1959
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	644	1.000	Inparanoid score	I436
Isobase	1	0.950	-	0	Normalized mean entropy	S4230
OMA	1	1.010	-	-		QHG55625
OrthoDB	1	1.010	-	-		D201312at2759
OrthoFinder	1	1.000	-	-		FOG0001724
OrthoInspector	1	1.000	-	-		otm14669
orthoMCL	1	0.900	-	-		OOG6_101099
Panther	1	1.100	-	-	O	PTHR11607
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X1279
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	14	13.760