Protein Alignment LManIV and man2a2

DIOPT Version :9

• Sequence 1: NP_609251.2
• Gene: LManIV / 34204
• FlyBaseID: FBgn0032067
• Length: 978
• Species: Drosophila melanogaster
• Sequence 2: XP_009296075.1
• Gene: man2a2 / 100333987
• ZFINID: ZDB-GENE-110331-1
• Length: 1174
• Species: Danio rerio
• Alignment Length: 1091
• Identity: 272/1091 - (24%)
• Similarity: 444/1091 - (40%)
• Gaps: 236/1091 - (21%)

  Fly    38 VNIHLVPHSHNDVGWLKTVDQSYYGYKNKIHHAGVQYILDSVVSQLLQDPKRRFIQVETAFFAKW 102
            :.:.:|||||||.||:||.|: ||..:       .|:||:::|:::.:||:|:||..|.::||||
Zfish   166 LQVFVVPHSHNDPGWIKTFDK-YYNDQ-------TQHILNNMVTKMAEDPRRKFIWSEISYFAKW 222

  Fly   103 WNVQSESMKKVVTKLVNEGRFEFTGGAWSMNDEANVNYQGVIDQFTVGLKFLNETFGSCGRPRVG 167
            |.......::|:.||:..|:.|...|.|.|.||||.:|..:|||...|.::|....|.  .||.|
Zfish   223 WESADVHKQEVMRKLILSGQLEMVTGGWVMTDEANAHYFAMIDQLIEGHQWLERNLGV--TPRSG 285

  Fly   168 WQIDTFGHSREQAAIFAHMGYDGQFFSRMDHNDKD----TRMNDLTMEMIWDASESMSGVSLFSG 228
            |.:|.||||.....:............|:.::.|.    ||..:......||..   |...:|..
Zfish   286 WAVDPFGHSATMPYLLKRANISSMLIQRVHYSIKKHFAATRSLEFMWRQAWDIE---SSTDMFCH 347

  Fly   229 MLYNFYS-DTPGFCF---DILCT-DQPIIDGDS------------EENNVKQRVDDFISYAKNVS 276
            |: .||| |.|..|.   .|.|. |...:.|..            .:.||.:|....:...:..|
Zfish   348 MM-PFYSYDVPHTCGPDPKICCQFDFKRLPGSRVNCPWKVPPRAINDANVAERAGVLLDQYRKKS 411

  Fly   277 EVYITNHIMVPMGGDFQYEDA---KVNYKNMDKLIKYINERQASGSKYNIFYSTPSCYLNSLHQS 338
            :::.:..::||:|.||:|:.|   ...|.|..||..|:|.......|..  ::|.|.|.::::::
Zfish   412 KLFRSKVLLVPLGDDFRYDKALEWDQQYLNYQKLFDYMNSHPEMHVKAQ--FATLSDYFDAVYKA 474

  Fly   339 --------LESWPNKTQDFFPYAHEKNSFWTGFFTSRPTQKRFERDGNHMLQVAKQLSVLANLTS 395
                    ...:|..:.|||.||..::.:|:|::||||..|..:|.....|:.|:.|..||...:
Zfish   475 NGVTSGARPPDYPVLSGDFFAYADREDHYWSGYYTSRPFYKNLDRILESHLRGAEILYSLAVAHA 539

  Fly   396 EEHKID-----LDY-----LRQVMGVMQHHDAITGTEKQAVSDDYDRMMYEAIVGASN---NA-- 445
            ....::     .||     .|:.:|:.|||||||||.|:||..||...:..::||...   ||
Zfish   540 RHAGVEGRYPVSDYSLLTDARRNIGLFQHHDAITGTAKEAVVIDYGNRLLRSLVGLKRVIINAAH 604

  Fly   446 ------RDALRLLTNMPYGEFESCLRLNISECAFTKDG-ADNVLV---------TLYNPLAHSST 494
                  :|..|.....|:        |...:...|:|. ....|:         .|:||:.....
Zfish   605 FLIIKNKDIYRFYQTEPF--------LETDDRRATQDSLPQRTLIELESSPRYLVLFNPVEQERL 661

  Fly   495 QYVRIPVKEENYQVTDEKGRTVPSEVVPVPWQVLALEYRSNDTQHELVFKATV------------ 547
            ..|.:.|.....:|..|.|:|:|.:        |:.::.|.......|::|:.
Zfish   662 CLVTVLVNSARVRVLTEDGQTLPVQ--------LSAQWMSATEMSGEVYQASFMARLPALGLAVF 718

  Fly   548 ---------NKVSSYSIKKVESSEVKHSSIKKINPREDNNSETV------VENSVVKLVMDNHTG 597
                     ..:.|.::.:|..   :..||:.::|. ...|:||      :::..:.|.....||
Zfish   719 HLYDSADSPMTLRSETLLRVPG---RGQSIRGLDPL-PVRSQTVDGQPFYIQSQSLTLGFSGATG 779

  Fly   598 RLKSVEMNGVSEKI-VQ----NFGVYKS-HTSCAYTFRQDGDIELFENDFE--FTVYEGSLVKEV 654
            .|:|:......::: ||    .:|...| ..|.||.|..||:.:.:.....  ..|.||.|..||
Zfish   780 LLESIRRKDDPQEVRVQIQFLTYGTRPSKDKSGAYLFLPDGNAKPYSQREAPIVRVVEGPLFAEV 844

  Fly   655 HQHVNDWISQVIRIYE--GVSRVELEWMVGPIPIDDKLGSEFVTNFKSEISSNGVFYTDSNGREL 717
            ..|...: .|.:||:.  ||..:.|: :...:.|.|:...|....|.::|.|...||||.||.::
Zfish   845 VAHYQHF-QQTVRIHNVPGVDGLSLD-ITTMVDIRDQNNKELAMRFVTDIQSGDTFYTDLNGFQI 907

  Fly   718 MKRVKDKREDFVSDLSRQPVSGNFYPVTSRIALQDDTKRLVLLNDRSQGGASLEDGALEMLIHRR 782
            ..|         ....:.|:..||||:.|...:||...||.|...::.|..||..|.||:::.||
Zfish   908 QPR---------RYFQKLPLQANFYPMPSTAYIQDSQYRLTLHTAQALGVTSLASGQLEVILDRR 963

  Fly   783 HLFNDGGGVGEALNETQYGKGLIARGKLYLILDSATD--------------------GDTVTERK 827
            .:.:|..|:|:.|.:.:.     ...:..|:|:..::                    ||...|..
Zfish   964 LMQDDNRGLGQGLKDNKR-----TANRFRLLLERRSNSAKPAGSYANMLNKIIAGILGDGQEEPV 1023

  Fly   828 TEKELFLPFWKFFS---------KTGGVEITPSKS--------LPDFNDLPQSVHLLTLEFFSEQ 875
            ..:.:..|  ...|         :...:.:.|.|.        .|....||...|||.|......
Zfish  1024 DSRPVSFP--SLLSHMTSTILNHEVLALPVLPRKHGVPPMRTFAPLAGTLPCDFHLLNLRSIQSP 1086

  Fly   876 E---------ILIRFEHFLDKS-EGRVISFNIRDIFDSLGGLAIRETTLDGNMPLSDMKRFKFHA 930
            :         .|:.....||.. |.:...||.              ||..|.:.:|.:.|
Zfish  1087 QDAHSPSPYMALLLHRLGLDCGLEPQNPGFNC--------------TTTQGQLSVSGLFR----- 1132

  Fly   931 QESG-----TKPSSVEYSTAQHKPLEAVKSDEASLFAVTLYPMQIRTFIIK 976
               |     .:|.|:....:| .||    |:::|   |:|.||:|..:.:|
Zfish  1133 ---GLDLQLLQPMSLSLMHSQ-PPL----SNDSS---VSLEPMEISAYKLK 1172

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
LManIV	NP_609251.2	GH38N_AMII_LAM_like	39..312	CDD:212121	92/296 (31%)
		Alpha-mann_mid	359..434	CDD:214875	31/84 (37%)
		Glyco_hydro_38C	483..973	CDD:285047	126/587 (21%)
man2a2	XP_009296075.1	PLN02701	128..1173	CDD:178304	272/1091 (25%)
		CE4_SF	165..508	CDD:301698	105/357 (29%)
		Alpha-mann_mid	503..588	CDD:214875	31/84 (37%)
		Glyco_hydro_38C	741..1169	CDD:285047	110/476 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910