DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment LManIII and AT5G13980

DIOPT Version :9

Sequence 1:	NP_001285762.1	Gene:	LManIII / 34203	FlyBaseID:	FBgn0032066	Length:	1003	Species:	Drosophila melanogaster
Sequence 2:	NP_196902.2	Gene:	AT5G13980 / 831246	AraportID:	AT5G13980	Length:	1024	Species:	Arabidopsis thaliana

Alignment Length:	1063	Identity:	378/1063 - (35%)
Similarity:	547/1063 - (51%)	Gaps:	112/1063 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MSSVKNLAILLALFASYIVQSEAVCYESCPETKSNMINIHLVPHSHDDLGWLKTVDQYYYGNKHN 65
            |...|.|..::.|....:|:|..:.|.:........:|:|:|||||||:||||||||||.|:.::
plant     1 MDLAKFLCWIVLLLGISLVESRYMVYNTSHTIVPGKLNVHVVPHSHDDVGWLKTVDQYYVGSNNS 65

  Fly    66 IQHAGVQYIFDTVVAELSKDSRRRFIQVETGFFAKWWEDQSETKKKLVKTLVNEGRLEFTGGAWS 130
            ||.|.||.:.|::|..|..|..|:||.||..||.:||.:|||..|::||.|::.|:||...|...
plant    66 IQVACVQNVLDSIVPALLADKNRKFIYVEQAFFQRWWNEQSEEIKRIVKELIHSGQLELINGGMC 130

  Fly   131 MNDEAAVNYQSVIDQFAVGLKFLNDNFGVCGRPRVGWQIDAFGHSREQASMF-AQMAFDGQFFAR 194
            |:||||.:|..:|||..:|.:|:...|.|  .||:|||||.||||..||.:. |::.||..||.|
plant   131 MHDEAAPHYIDMIDQTTLGHRFIIREFNV--TPRIGWQIDPFGHSAVQAYLLGAEVGFDSVFFGR 193

  Fly   195 MDQNDKNKRVDNLGLEMVWDASETL-EEMDFFTGMLYNHYSAPPGFCFDSLCQDDPII--DGKSY 256
            :|..|:.||.....||::|..|::| .....|.|....:|..|||..:..:..|.|::  |...:
plant   194 IDYQDREKRYKEKTLEVIWRGSKSLGSSSQIFAGAFPTNYEPPPGGFYYEITDDSPVVQDDPDLF 258

  Fly   257 DNNVKSRVDDFLNYASNLAGYYRSNHIMVPMGDDFQYENAYMNYKNMDKLIKYVNERQASGSKYN 321
            |.||:.||:.|:..|.:.|...|.||||..||.||:|:.|:..|:.|||||.|||    ...:.|
plant   259 DYNVQERVNAFVAAALDQANITRINHIMFTMGTDFRYQYAHTWYRQMDKLIHYVN----LDGRVN 319

  Fly   322 IFYSTAGCYLNSLHKSLQSFPNKTQDFLPHSHEAKSFWTGFFTSRPTQKRFERDGNHILQVAKQL 386
            .||||...|.::.|.:.:::|.||:|:.|::....::|||:|||||..||:.|..:.....|:||
plant   320 AFYSTPSIYTDAKHAANEAWPLKTEDYFPYADRINAYWTGYFTSRPALKRYVRVMSAYYLAARQL 384

  Fly   387 SVLADLSGEEQHKDLDYLRQIMAVMQHHDAITGTEKQEVSNDYDRLLYDAILGGANTARDALRVL 451
            ......|  ::..:.|.|...:|:.|||||::||.||.|:|||.:.|....:...:....:|..|
plant   385 EFFKGRS--QKGPNTDSLADALAIAQHHDAVSGTSKQHVANDYAKRLAIGYVEAESVVATSLAHL 447

  Fly   452 TN-QP--NGEFQSCLKLNISECAFTKENADD---FMVTLYNPLAHTSTQYVRVPVKEDSYQVTDE 510
            |. .|  |..||.||.||||.|..::.|..|   .:|..||||.......||:||......|.|.
plant   448 TKVDPTLNPTFQQCLLLNISYCPSSEVNLSDGKSLIVLAYNPLGWKRVDIVRLPVVGGDVSVHDS 512

  Fly   511 KGGLVASELVPVPWEVLSLE-------FRNNDTQ---HELVFKASVNKI--ATYFI---KKIDKT 560
            :|..|.|:|||...|.::|.       ...:.||   :.|||..:|..:  .||.|   ||.|..
plant   513 EGHEVESQLVPFTDEYVALRKYHVEAYLGQSPTQVPKYWLVFSVTVPPLGFTTYTISTAKKTDGY 577

  Fly   561 TEVDITVN-TQTEQS-VNEEESNVKVPKRFKKVHSLKTDLETLDDQETIVQNSLIKLVIDNNTGR 623
            :......| .:.||| :|....::|:        |..||           |.:.|..|    .||
plant   578 SSKSYVSNILKGEQSIINIGHGHLKL--------SFSTD-----------QGTAINYV----NGR 619

  Fly   624 LKTVEMNGVSEDIDQTFGMYKT------------ARSCHYIFRQDADLEL-VEDAFDFTVYDGES 675
                  ..::|.:.|||..|..            ..|..|:||.:....: .|.....||..|..
plant   620 ------TSMTEPVKQTFSYYSAYNGSNDKEPLIPQNSGAYVFRPNGTFPINPEGQVPLTVIHGPL 678

  Fly   676 VKEVHQHVNEWISQVIRIYEGVNRVEFEWLVGPVPIDDELGKEIVTIFKSGISSGGVFYTDSNGR 740
            |.||||.:|.||||:.|:|:|...||.|::||.:||||.:|||:||...|.:.|...|||||:||
plant   679 VDEVHQQINPWISQITRVYKGKEHVEVEFIVGNIPIDDGIGKEVVTQISSSLKSNKTFYTDSSGR 743

  Fly   741 EMMRREKDKREDFSPDLSEQPVSGNYYPVTSRMALQDSSKRMVLLNDRSQGGASLEDGRLEMMLH 805
            :.::|.:|.|.|:..|:: ||::|||||:...:.||||.|...::.||:.||:|:.||::|:|||
plant   744 DYIKRIRDYRSDWKLDVN-QPIAGNYYPINHGIYLQDSKKEFSVMVDRAFGGSSIVDGQVELMLH 807

  Fly   806 RRHIFADGSGAAEAINE----QQFGKGLIARGKLFLYLNAIEDGATASERVAEKEIHLPFWKFFS 866
            ||.:..|..|.||.:||    |....||..:||.:..::...:|| ...|...:||:.|....|:
plant   808 RRLLLDDSRGVAENLNETVCVQDKCTGLTIQGKYYYRIDPYGEGA-KWRRTFGQEIYSPLLLAFA 871

  Fly   867 KSNNIQSDVTKTLS----DFN------DLPQSVHLLTLEPYSKDEILLRLENFLDQTE----GNV 917
                 |.|..|.:|    .|:      .||.:|.||||:......:||||.:..:..|    ..|
plant   872 -----QQDDGKPMSFGAASFSGIDPSYSLPDNVALLTLQELDDGNVLLRLAHLYEVEEDKELSGV 931

  Fly   918 VSFSIRQIFDDLGGLEIRETTLDGNLPLSDM--KRLKFHHDGSGPSHSVPEYFTSLHKPLAADKT 980
            .|..::::|......::.|.:|..|...|.|  |||.:..:|.|   |..|     .|.....:.
plant   932 ASVELKKLFPGKKIGKLTEMSLSANQERSTMEKKRLVWKVEGEG---SYGE-----EKKAKRGRE 988

  Fly   981 QDASEFSVTLKPMQIRTFIIKKE 1003
            .|..:..:.|.||:|||.:|..|
plant   989 IDPRKLEMELYPMEIRTVLIHLE 1011

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
LManIII	NP_001285762.1	GH38N_AMII_LAM_like	37..311	CDD:212121	125/277 (45%)
		Alpha-mann_mid	358..433	CDD:286360	31/74 (42%)
		Glyco_hydro_38C	603..998	CDD:285047	141/427 (33%)
AT5G13980	NP_196902.2	PLN02701	36..820	CDD:178304	313/821 (38%)
AT5G13980	NP_196902.2	GH38N_AMII_LAM_like	37..313	CDD:212121	125/277 (45%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	310	1.000	Domainoid score	I311
eggNOG	1	0.900	-	-		E1_KOG1959
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	649	1.000	Inparanoid score	I170
OMA	1	1.010	-	-		QHG55625
OrthoDB	1	1.010	-	-		D201312at2759
OrthoFinder	1	1.000	-	-		FOG0001724
OrthoInspector	1	1.000	-	-		mtm1010
orthoMCL	1	0.900	-	-		OOG6_101099
Panther	1	1.100	-	-	O	PTHR11607
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X1279
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	14	13.840