Protein Alignment LManIII and man2a2

DIOPT Version :10

• Sequence 1: NP_609250.2
• Gene: LManIII / 34203
• FlyBaseID: FBgn0032066
• Length: 1003
• Species: Drosophila melanogaster
• Sequence 2: NP_001006777.1
• Gene: man2a2 / 448465
• XenbaseID: XB-GENE-981388
• Length: 909
• Species: Xenopus tropicalis
• Alignment Length: 804
• Identity: 221/804 - (27%)
• Similarity: 356/804 - (44%)
• Gaps: 154/804 - (19%)

  Fly    31 ETKSNMINIHLVPHSHDDLGWLKTVDQYYYGNKHNIQHAGVQYIFDTVVAELSKDSRRRFIQVET 95
            |..:..:.:.:|||||:|.||:||.|:|||..        .|:|.:.:|.:|.:|.||:||..|.
 Frog   160 EWDNEPLQVFVVPHSHNDPGWIKTFDKYYYDQ--------TQHILNNMVVKLHEDPRRKFIWSEI 216

  Fly    96 GFFAKWWEDQSETKKKLVKTLVNEGRLEFTGGAWSMNDEAAVNYQSVIDQFAVGLKFLNDNFGVC 160
            .||:|||::.:..|:..|:.||..|:||.|.|.|.|.|||..:|.::|||...|.::|..|..
 Frog   217 SFFSKWWDNINSQKRAAVRRLVASGQLEMTTGGWVMPDEANTHYFAMIDQMIEGHQWLKKNLD-- 279

  Fly   161 GRPRVGWQIDAFGHSREQASMFAQMAFDGQFFARMDQNDKNKRVDNLGLEMVW------DASETL 219
            ..||.||.:|.||||.....:..:.........|:..:.|........||.:|      |:|
 Frog   280 ATPRSGWAVDPFGHSSTMPYILRRSNLTSMLIQRVHYSIKKHFAATQSLEFMWRQTWDPDSS--- 341

  Fly   220 EEMDFFTGML-YNHYSAP------PGFCFDSLCQDD-------------PIIDGKSYDNNVKSRV 264
              .|.|..|: :..|..|      |..|    ||.|             .:......|:||..|.
 Frog   342 --TDIFCHMMPFYSYDVPHTCGPDPKIC----CQFDFRRLPGGRINCPWKVPPRAITDSNVAERA 400

  Fly   265 DDFLNYASNLAGYYRSNHIMVPMGDDFQYEN------AYMNYKNMDKLIKYVNER-----QASGS 318
            :..|:.....:..|||..::||:||||:|:.      .::||:   ||..|:|..     ||.
 Frog   401 NILLDQYKKKSKLYRSKVVLVPLGDDFRYDKIQEWDAQFLNYQ---KLFDYMNSHPELHVQAQ-- 460

  Fly   319 KYNIFYSTAGCYLNSLHKSL--------QSFPNKTQDFLPHSHEAKSFWTGFFTSRPTQKRFERD 375
                 :.|...|.::|:|.:        ..||..:.||..::.....:|||::||||..|..:|.
 Frog   461 -----FGTLSDYFDALYKRMGVVPGIKPPDFPVVSGDFFSYADREDHYWTGYYTSRPFYKSMDRV 520

  Fly   376 GNHILQVAKQLSVL----ADLSGEEQHKDL-DY-----LRQIMAVMQHHDAITGTEKQEVSNDYD 430
            ....|:.|:.|..|    |..:|.|....| ||     .|:.:.:.|||||||||.|:.|..||.
 Frog   521 LESHLRGAEILYSLAINHARKAGTESKYPLSDYALLTDARRNLGLFQHHDAITGTAKEAVVIDYG 585

  Fly   431 -RLLYDAILGGANTARDALR-----VLTNQPNGEFQSCLK-LNISECAFTKEN----------AD 478
             |||:..:    |..|..:.     |:.::....:...:. .:..|...|:|:          |.
 Frog   586 VRLLHSLM----NLKRIIINAAHYLVVADKEKYHYDHSVPFFSTDESRLTQESLPEKTVIKLTAS 646

  Fly   479 DFMVTLYNPLAHTSTQYVRVPVKEDSYQVTDEKGGLVASELVPVPWEVLSLEFRNNDTQHELVFK 543
            ...|.::||:.......|.:.|...:.:|..|.|..||::|.|| |:  |:...|.|. :::.|.
 Frog   647 PRYVVVFNPVEQNRLCVVSLLVNTYNVRVLTEDGQPVAAQLSPV-WQ--SVTDMNPDV-YQVSFT 707

  Fly   544 ASVNKIATYFIKKIDKTTEVDITVNTQTEQSVNEEESNVKVPKRFKKVHSLKTDL-------ETL 601
            |.:..:.....       ::..:::|.|..     :|||:|....:::...|.|:       .:.
 Frog   708 ARLPSLGLSIF-------QLHASIDTHTTL-----KSNVRVHLHGRELSIKKQDVFPVKVAESST 760

  Fly   602 DDQETIVQNSLIKLVIDNNTGRLKTVEMNGVSED--IDQTFGMYKTA----RSCHYIFRQDADLE 660
            ||..  ::|..:::.....||.||:::..|..::  |:..|.:|.|.    :|..|:|..|.:.:
 Frog   761 DDFH--IENQYMQVWFSGTTGLLKSIKRAGEEQEQKINMQFLIYGTRTSKDKSGAYLFLPDGEAK 823

  Fly   661 --LVEDAFDFTVYDGESVKEV---HQHVNEWISQVIRIY-----EGVNRVEFEWLVGPVPIDDEL 715
              ..:|.....|.:|....||   :|||    .||:|:|     ||:: ::...|   :.|.|.:
 Frog   824 PYTPKDPPVVKVTEGPFYSEVTCQYQHV----QQVMRLYNLPGTEGLS-LDISSL---IDIRDHV 880

  Fly   716 GKEIVTIFKSGISSGGVFYTDSNG 739
            .|||.....:.|.|..:|:||.||
 Frog   881 NKEIAMRLSTDIQSEDIFFTDLNG 904

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
LManIII	NP_609250.2	PLN02701	20..820	CDD:178304	221/804 (27%)
		GH38N_AMII_LAM_like	37..311	CDD:212121	96/305 (31%)
man2a2	NP_001006777.1	PLN02701	128..>906	CDD:178304	221/804 (27%)