Protein Alignment LManIII and aman-1

DIOPT Version :10

• Sequence 1: NP_609250.2
• Gene: LManIII / 34203
• FlyBaseID: FBgn0032066
• Length: 1003
• Species: Drosophila melanogaster
• Sequence 2: NP_508811.1
• Gene: aman-1 / 180749
• WormBaseID: WBGene00018877
• Length: 955
• Species: Caenorhabditis elegans
• Alignment Length: 1002
• Identity: 327/1002 - (32%)
• Similarity: 506/1002 - (50%)
• Gaps: 99/1002 - (9%)

  Fly     6 NLAILLALFASYIVQSEAVC-YESCPETKS--NMINIHLVPHSHDDLGWLKTVDQYYYGNKHNIQ 67
            ||.::.......::.|...| :.:|.:...  |:|..||:||:||||||:||||||::|.|..:.
 Worm     2 NLQVIFLFLGLLVIYSSQDCAWNTCHKVDQDPNVITAHLIPHTHDDLGWIKTVDQYFWGAKPELV 66

  Fly    68 HAGVQYIFDTVVAELSKDSRRRFIQVETGFFAKWWEDQSETKKKLVKTLVNEGRLEFTGGAWSMN 132
            ..|||||::||:.||.|:..|||...||||..:|:...|:..:..::.||..|::|..||.|..|
 Worm    67 PVGVQYIYNTVIDELLKNPDRRFSFAETGFLWRWYTSNSDFDRHQLQKLVKNGQIEIIGGGWVQN 131

  Fly   133 DEAAVNYQSVIDQFAVGLKFLNDNFGVCGRPRVGWQIDAFGHSREQASMFAQMAFDGQFFARMDQ 197
            |||..:|..:|||..:||:.|...||.||:|..|||||.||||||.|:::.:|.:...:|||:..
 Worm   132 DEATSHYVDIIDQMTLGLQRLEQIFGECGKPVTGWQIDPFGHSREMANIYREMGYSSVYFARIHY 196

  Fly   198 NDKNKRVDNLGLEMVWDASETLEEMDFFTGMLYN-HYSAPPGFCFDSLCQDDPIIDGKSYDN-NV 260
            .:|..|:.|..||.:|:.|:.:.:...|||..:| :|..|.|||:||||.||||:|..:.:. ||
 Worm   197 LEKQIRLKNKTLEFMWNTSDDITDNKLFTGAFFNDNYGPPEGFCWDSLCGDDPIMDNLNIEGYNV 261

  Fly   261 KSRVDDFLNYASNLAGYYRSNHIMVPMGDDFQYENAYMNYKNMDKLIKYVNERQASGSKYNIFYS 325
            |.:||.|:::..|.|.:..:|.:|:.||.||||.||...|.|:||||||||  ..:..|..:.||
 Worm   262 KEKVDAFVDHVKNQAAHQSTNQVMLLMGSDFQYTNANSWYVNLDKLIKYVN--ADTSKKVRVIYS 324

  Fly   326 TAGCYLNSLHKSLQSFPNKTQDFLPHSHEAKSFWTGFFTSRPTQKRFERDGNHILQVAKQLSVLA 390
            |..||..::.....:...|..||.|::....|:|||:|||||..|...|..:.:||:||||.|:|
 Worm   325 TPACYTKAVQAKTPTLSVKHDDFFPYASGRHSYWTGYFTSRPAFKGMIRQASCMLQLAKQLDVIA 389

  Fly   391 DLSGEEQHKDLDYLRQIMAVMQHHDAITGTEKQEVSNDYDRLLYDAILGGANTARDALRVLTNQP 455
            :| |.|...|::.||:..|::|||||:|||.|:.|:.||::.|...:........|.::.:  .|
 Worm   390 NL-GPEDDSDIEILREASALVQHHDAVTGTAKENVTRDYEKQLAKGVSEVEVVINDFMKKM--NP 451

  Fly   456 NG---EFQSCLKLNISECAFTKENADDFMVTLYNPLAHTSTQYVRVPVKEDSYQVTDEKGGLVAS 517
            :|   :...|..:|.:.|. ....:.:|.|.::|.........:|:|..:.:..:.|....::.|
 Worm   452 DGLDPKLVLCPLINETICK-PINGSSEFSVVIFNSNGRYFNGTIRIPYSQKTAVLRDAHKNVLES 515

  Fly   518 ELVP------------VPWEVLSLEFRNNDTQHELVFKASVNKIATYFIKKIDKTTEVDITVNTQ 570
            ::|.            :|:|:           |..| :.......|.|::|..|...|..  |.:
 Worm   516 QIVETFQIDQLKDTDRLPYEI-----------HVFV-RVPPLGYTTVFVEKGSKPERVHF--NNR 566

  Fly   571 TEQSVNEEESNVKVPKRFKKVHSLKTDLETLDDQETIVQNSLIKLVIDNNTGRLKTVEM-----N 630
            .:.:.|.|..|..:...|             |.|      ..:..:.:..|.:.:::..     .
 Worm   567 KKFNTNVEIQNEYLIAGF-------------DSQ------GYLSYITEKATKKKRSIRQEFFYYE 612

  Fly   631 GVSEDIDQTFGMYKTARSCHYIFRQDADLEL-VEDAFDFTVYDGESVKEVHQHVNEWISQVIRIY 694
            |:....||..|.        ||||......: :.......|..|..:.||.|.|:.::||.||:.
 Worm   613 GIDSKDDQPSGA--------YIFRPKTQQPIALTSKLALEVVPGAIINEVRQKVSPFVSQQIRLP 669

  Fly   695 EGVNRVEFEWLVGPVPID--DELGKEIVTIFKSGISSGGVFYTDSNGREMMRREKDKREDFSPDL 757
            .|.|.:||||:|||:|.:  :.:.||.||.:.:.:.|....:||||||:.|.|..|....|....
 Worm   670 RGKNYIEFEWIVGPIPKETKNPITKEFVTRYTTEVHSKNQSFTDSNGRQAMERFFDGATSFEYSD 734

  Fly   758 SEQPVSGNYYPVTSRMALQDSSKRMVLLNDRSQGGASLEDGRLEMMLHRRHIFADGSGAAEAINE 822
            :| |::|||||:||...::|.:.:..::.||:||..: .||.:|:|||||..:.|..|..||::|
 Worm   735 TE-PIAGNYYPITSFGYIKDENAQFSVITDRAQGMVA-SDGVVEIMLHRRCFYDDHFGVEEALDE 797

  Fly   823 Q-QFGKGLIARGKLFLYLNAIEDGATASERVAEKEIHLPFWKFFSKSNNIQSDVTKTLSDFN--- 883
            . :.|.||:|.||..:....::...:....:|....|.|...|   :.|.:......|.:::
 Worm   798 PGKDGAGLVAMGKHIVLFTDVKASTSQLRPLAIDNFHQPVLAF---NKNPEKFEFNRLLEYSGLK 859

  Fly   884 -DLPQSVHLLTLEPYSKDEILLRLENFLDQTEGN-VVSFSIRQIFDDLGGLEIRETTLDGNLPLS 946
             :||..:||||||.:.|...|:|.||.....||| :..|....||.:...:..:|..|..|..:.
 Worm   860 FELPIGIHLLTLEKWHKKSSLIRFENIYHGEEGNSIKEFDPTHIFTNFDIVSFKELLLGANRVVG 924

  Fly   947 DMKRLKFHHDGSGPSHSVPEYFTSLHK 973
            ..|.       ||.|      |.|..|
 Worm   925 KNKE-------SGSS------FRSFEK 938

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
LManIII	NP_609250.2	PLN02701	20..820	CDD:178304	282/827 (34%)
		GH38N_AMII_LAM_like	37..311	CDD:212121	128/275 (47%)
aman-1	NP_508811.1	PLN02701	23..871	CDD:178304	299/899 (33%)
		GH38N_AMII_LAM_like	36..313	CDD:212121	130/278 (47%)