Protein Alignment IDH3B and CG5028

DIOPT Version :9

• Sequence 1: NP_001317692.1
• Gene: IDH3B / 3420
• HGNCID: 5385
• Length: 387
• Species: Homo sapiens
• Sequence 2: NP_001097922.1
• Gene: CG5028 / 43102
• FlyBaseID: FBgn0039358
• Length: 402
• Species: Drosophila melanogaster
• Alignment Length: 391
• Identity: 160/391 - (40%)
• Similarity: 243/391 - (62%)
• Gaps: 17/391 - (4%)

Human    10 LTRALVSAGNPGAWRGL-------STSAAAHAASRSQAE-------DVRVEGSFPVTMLPGDGVG 60
            ||:.|:....|...||.       .|...||..|..|.:       ..:..|...||||||.|:|
  Fly     5 LTQRLLQTQTPFLTRGYPLLVTKEKTEDVAHTKSALQKKVTGTDIPSAQYGGRHAVTMLPGGGIG 69

Human    61 PELMHAVKEVFKAAAVPVEFQEHHLSEVQNMASEEKLEQVLSSMKENKVAIIGKIHTPMEYKGEL 125
            ||||..|:|:|:....|::|:...:.  .:....:.|:..::|:|.|.||:.|.|.|..:...|:
  Fly    70 PELMGYVREIFRYCGAPIDFEVIDID--PSTEGNDDLDYAITSIKRNGVALKGNIETKSQSLTEV 132

Human   126 ASYDMRLRRKLDLFANVVHVKSLPGYMTRHNNLDLVIIREQTEGEYSSLEHESARGVIECLKIVT 190
             |.::.:|.:|||:.||||.||.||...||:::|:|:||:.|:|||:.|||||..|::|.:|:||
  Fly   133 -SRNVAIRNELDLYVNVVHCKSYPGIPARHHDIDVVLIRQNTDGEYAMLEHESVPGIVESMKVVT 196

Human   191 RAKSQRIAKFAFDYATKKGRGKVTAVHKANIMKLGDGLFLQCCEEVAELYPKIKFETMIIDNCCM 255
            ...::|:|::||::|.:..|.|||.:||||||||.|||||:....|.:.||:::...|||||.||
  Fly   197 VENAERVARYAFEFARQNNRKKVTTIHKANIMKLSDGLFLEVANRVHKDYPELEHNNMIIDNTCM 261

Human   256 QLVQNPYQFDVLVMPNLYGNIIDNLAAGLVGGAGVVPGESYSAEYAVFETGARHPFAQAVGRNIA 320
            |.|.||:||||:.|.||||.|:.|:..||:||||::.|.:|...||:||.|.|:......|:|||
  Fly   262 QSVSNPHQFDVMNMTNLYGTIVSNVLCGLMGGAGLISGRNYGDHYAIFEPGTRNTGTAIAGKNIA 326

Human   321 NPTAMLLSASNMLRHLNLEYHSSMIADAVKKVIKVGKVRTRDMGGYSTTTDFIKSVIGHLQTKGS 385
            ||.||:.::.:||.||..:.|:::|.:||.:.|....:||.|:||.:::||.:::::..|..|..
  Fly   327 NPVAMISASIDMLNHLGHKEHANVIQEAVYQTIVNDAIRTPDIGGTNSSTDVVENILKILSAKRV 391

Human   386 N 386
            |
  Fly   392 N 392

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
IDH3B	NP_001317692.1	None
CG5028	NP_001097922.1	mito_nad_idh	55..386	CDD:272942	146/333 (44%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0473
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53770
OrthoDB	1	1.010	-	-		D325037at33208
OrthoFinder	1	1.000	-	-		FOG0000244
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_101342
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R585
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	7	6.760