DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG9314 and Cat

DIOPT Version :9

Sequence 1:	NP_001260268.1	Gene:	CG9314 / 34198	FlyBaseID:	FBgn0032061	Length:	506	Species:	Drosophila melanogaster
Sequence 2:	NP_536731.1	Gene:	Cat / 40048	FlyBaseID:	FBgn0000261	Length:	506	Species:	Drosophila melanogaster

Alignment Length:	506	Identity:	356/506 - (70%)
Similarity:	424/506 - (83%)	Gaps:	0/506 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MCSRDTASNQLIDYKNNDSEVQREITTSSGTPVGVKDAIQTVGPRGPALLQDFQFLDEVMHFDSE 65
            |..||.||||||||||:.:.....|||.:|.|:|:|||.||||||||.||||..||||:.|||.|
  Fly     1 MAGRDAASNQLIDYKNSQTVSPGAITTGNGAPIGIKDASQTVGPRGPILLQDVNFLDEMSHFDRE 65

  Fly    66 RIPERVAYAKGAGAFGYFECTHDISKFCAASIFDKVRKRTAVAMRFSVACGEQGSADTVREQRGF 130
            ||||||.:|||||||||||.||||:::|||.|||||:|||.:|:|||...||.|||||.|:.|||
  Fly    66 RIPERVVHAKGAGAFGYFEVTHDITQYCAAKIFDKVKKRTPLAVRFSTVGGESGSADTARDPRGF 130

  Fly   131 AVKFYTDDGIWDIVGCNMPVHYVRDPMLFPSLVHAQKRNPQTHLKDPDMFWDFMTLRPETLHALL 195
            ||||||:||:||:||.|.||.::|||:||||.:|.||||||||||||||||||:|||||:.|.:.
  Fly   131 AVKFYTEDGVWDLVGNNTPVFFIRDPILFPSFIHTQKRNPQTHLKDPDMFWDFLTLRPESAHQVC 195

  Fly   196 MYFSDRGTPDGYRHLHGYGVHTYRMINASGETQYVRFHFKTDQGIKNLDARRCEELMSHDPDYAI 260
            :.||||||||||.|::|||.||:::|||.||..|.:|||||||||||||.:..::|.|.||||:|
  Fly   196 ILFSDRGTPDGYCHMNGYGSHTFKLINAKGEPIYAKFHFKTDQGIKNLDVKTADQLASTDPDYSI 260

  Fly   261 RDLYNSIKKGNYPSWSMYIQVMLNEEAKKCRFNPFDVTKVWPQKDFPLLPVGKIVLDRNPTNYFT 325
            |||||.||...:|||:||||||..|:|||.::|||||||||.||::||:||||:||||||.|||.
  Fly   261 RDLYNRIKTCKFPSWTMYIQVMTYEQAKKFKYNPFDVTKVWSQKEYPLIPVGKMVLDRNPKNYFA 325

  Fly   326 EVEQLAFSPAHMVPGIEPSPDKMLQGRLFAYGDSQRHRLGVNYMQIPVNCPYRVNVRNFQRDGAM 390
            ||||:||||||:|||:||||||||.||||:|.|:.|||||.||:||||||||:|.:.||||||||
  Fly   326 EVEQIAFSPAHLVPGVEPSPDKMLHGRLFSYSDTHRHRLGPNYLQIPVNCPYKVKIENFQRDGAM 390

  Fly   391 TVTDNQNGAPNYFPNSFCGPRESPRALGLQTCCPLSGDVYRFMSGDTEDNFSQVTDFWTYTLDNC 455
            .|||||:||||||||||.||:|.|||..|.:|||::|||||:.||||||||.||||||.:.||.|
  Fly   391 NVTDNQDGAPNYFPNSFNGPQECPRARALSSCCPVTGDVYRYSSGDTEDNFGQVTDFWVHVLDKC 455

  Fly   456 GRKRLVRNLSEHLTEASQFLQERAVKLFTMVHSDFGRLMTEALNTARISKF 506
            .:||||:|::.||:.|||||||||||.||.||:||||::||.||.|:.|||
  Fly   456 AKKRLVQNIAGHLSNASQFLQERAVKNFTQVHADFGRMLTEELNLAKSSKF 506

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9314	NP_001260268.1	KatE	10..501	CDD:223824	346/490 (71%)
		Catalase	28..406	CDD:278622	271/377 (72%)
		Catalase-rel	438..498	CDD:284128	41/59 (69%)
Cat	NP_536731.1	KatE	10..505	CDD:223824	347/494 (70%)
Cat	NP_536731.1	catalase_clade_3	66..498	CDD:163712	308/431 (71%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45473074
Domainoid	1	1.000	381	1.000	Domainoid score	I161
eggNOG	1	0.900	-	-		E1_COG0753
Homologene	1	1.000	-	-		H55514
Inparanoid	1	1.050	384	1.000	Inparanoid score	I519
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG62736
OrthoDB	1	1.010	-	-		D172396at33208
OrthoFinder	1	1.000	-	-		FOG0001359
OrthoInspector	1	1.000	-	-		otm25018
orthoMCL	1	0.900	-	-		OOG6_100495
Panther	1	1.100	-	-	P	PTHR11465
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X851
	13	12.810