DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG9314 and cat

DIOPT Version :9

Sequence 1:	NP_001260268.1	Gene:	CG9314 / 34198	FlyBaseID:	FBgn0032061	Length:	506	Species:	Drosophila melanogaster
Sequence 2:	NP_570987.2	Gene:	cat / 30068	ZFINID:	ZDB-GENE-000210-20	Length:	526	Species:	Danio rerio

Alignment Length:	497	Identity:	280/497 - (56%)
Similarity:	368/497 - (74%)	Gaps:	4/497 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 RDTASNQLIDYKNNDSEVQREI-TTSSGTPVGVKDAIQTVGPRGPALLQDFQFLDEVMHFDSERI 67
            |:.:::|:..:|......:.:: ||.:|.|:|.|....|.|||||.|:||..|.||:.|||.|||
Zfish     5 REKSTDQMKLWKEGRGSQRPDVLTTGAGVPIGDKLNAMTAGPRGPLLVQDVVFTDEMAHFDRERI 69

  Fly    68 PERVAYAKGAGAFGYFECTHDISKFCAASIFDKVRKRTAVAMRFSVACGEQGSADTVREQRGFAV 132
            ||||.:|||||||||||.||||:::..|.:|:.:.|.|.:|:|||...||.||:||||:.|||||
Zfish    70 PERVVHAKGAGAFGYFEVTHDITRYSKAKVFEHIGKTTPIAVRFSTVAGEAGSSDTVRDPRGFAV 134

  Fly   133 KFYTDDGIWDIVGCNMPVHYVRDPMLFPSLVHAQKRNPQTHLKDPDMFWDFMTLRPETLHALLMY 197
            |||||:|.||:.|.|.|:.::||.:||||.:|:||||||||||||||.|||.:||||:||.:...
Zfish   135 KFYTDEGNWDLTGNNTPIFFIRDTLLFPSFIHSQKRNPQTHLKDPDMVWDFWSLRPESLHQVSFL 199

  Fly   198 FSDRGTPDGYRHLHGYGVHTYRMINASGETQYVRFHFKTDQGIKNLDARRCEELMSHDPDYAIRD 262
            |||||.||||||::|||.||::::||.|:..|.:||:||:|||||:.....:.|.:.||||:|||
Zfish   200 FSDRGIPDGYRHMNGYGSHTFKLVNAQGQPVYCKFHYKTNQGIKNIPVEEADRLAATDPDYSIRD 264

  Fly   263 LYNSIKKGNYPSWSMYIQVMLNEEAKKCRFNPFDVTKVWPQKDFPLLPVGKIVLDRNPTNYFTEV 327
            |||:|..||:|||:.|||||..|:|:..::||||:||||..|:|||:|||:.||:|||.|||.||
Zfish   265 LYNAIANGNFPSWTFYIQVMTFEQAENWKWNPFDLTKVWSHKEFPLIPVGRFVLNRNPVNYFAEV 329

  Fly   328 EQLAFSPAHMVPGIEPSPDKMLQGRLFAYGDSQRHRLGVNYMQIPVNCPYRVNVRNFQRDGAMTV 392
            |||||.|::|.||||||||||||||||:|.|:.|||||.||:|:|||||||..|.|:||||.|.:
Zfish   330 EQLAFDPSNMPPGIEPSPDKMLQGRLFSYPDTHRHRLGANYLQLPVNCPYRTRVANYQRDGPMCM 394

  Fly   393 TDNQNGAPNYFPNSFCGPRESPRALGLQTCCPLSGDVYRFMSGDTEDNFSQVTDFWTYTLDNCGR 457
            .|||.|||||:||||..|...||.  |::.|.:|.||.|:.|.| :||.:||..|:|..|:...|
Zfish   395 HDNQGGAPNYYPNSFSAPDVQPRF--LESKCKVSPDVARYNSAD-DDNVTQVRTFFTQVLNEAER 456

  Fly   458 KRLVRNLSEHLTEASQFLQERAVKLFTMVHSDFGRLMTEALN 499
            :||.:|::.||..|..|:|:|.|:....||||:|..:...|:
Zfish   457 ERLCQNMAGHLKGAQLFIQKRMVQNLMAVHSDYGNRVQALLD 498

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9314	NP_001260268.1	KatE	10..501	CDD:223824	279/491 (57%)
		Catalase	28..406	CDD:278622	237/377 (63%)
		Catalase-rel	438..498	CDD:284128	23/59 (39%)
cat	NP_570987.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..29		3/23 (13%)
cat	NP_570987.2	catalase_clade_3	68..497	CDD:163712	254/431 (59%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170596766
Domainoid	1	1.000	57	1.000	Domainoid score	I10877
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H55514
Inparanoid	1	1.050	692	1.000	Inparanoid score	I668
OMA	1	1.010	-	-		QHG62736
OrthoDB	1	1.010	-	-		D172396at33208
OrthoFinder	1	1.000	-	-		FOG0001359
OrthoInspector	1	1.000	-	-		otm25018
orthoMCL	1	0.900	-	-		OOG6_100495
Panther	1	1.100	-	-	O	PTHR11465
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X851
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	13	12.910