DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG9314 and ctl-3

DIOPT Version :9

Sequence 1:	NP_001260268.1	Gene:	CG9314 / 34198	FlyBaseID:	FBgn0032061	Length:	506	Species:	Drosophila melanogaster
Sequence 2:	NP_741058.1	Gene:	ctl-3 / 175086	WormBaseID:	WBGene00013220	Length:	512	Species:	Caenorhabditis elegans

Alignment Length:	494	Identity:	264/494 - (53%)
Similarity:	343/494 - (69%)	Gaps:	9/494 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 ASNQLIDYKNNDSEVQREITTSSGTPVGVKDAIQTVGPRGPALLQDFQFLDEVMHFDSERIPERV 71
            |.:||..|::.:.| ...:|||:|.|:..|.|:.|.|.|||.|:||..::||:.|||.|||||||
Worm    21 AEDQLKAYRDRNQE-PHLLTTSNGAPIYSKTAVLTAGRRGPMLMQDIVYMDEMAHFDRERIPERV 84

  Fly    72 AYAKGAGAFGYFECTHDISKFCAASIFDKVRKRTAVAMRFSVACGEQGSADTVREQRGFAVKFYT 136
            .:|||.||.||||.||||:|:|.|.:|:||.|:|.:.:|||...||.|||||||:.|||::||||
Worm    85 VHAKGGGAHGYFEVTHDITKYCKADMFNKVGKQTPLLVRFSTVAGESGSADTVRDPRGFSLKFYT 149

  Fly   137 DDGIWDIVGCNMPVHYVRDPMLFPSLVHAQKRNPQTHLKDPDMFWDFMTLRPETLHALLMYFSDR 201
            ::|.||:||.|.|:.::||.:.||:.:||.|||||||::||:..:||...|||::|.::..:|||
Worm   150 EEGNWDLVGNNTPIFFIRDAIHFPNFIHALKRNPQTHMRDPNALFDFWMNRPESIHQVMFLYSDR 214

  Fly   202 GTPDGYRHLHGYGVHTYRMINASGETQYVRFHFKTDQGIKNLDARRCEELMSHDPDYAIRDLYNS 266
            |.|||:|.::|||.||::|:|..|...|.:||||..||.||||.....:|.|.|||||||||:|:
Worm   215 GIPDGFRFMNGYGAHTFKMVNKEGNPIYCKFHFKPAQGSKNLDPTDAGKLASSDPDYAIRDLFNA 279

  Fly   267 IKKGNYPSWSMYIQVMLNEEAKKCRFNPFDVTKVWPQKDFPLLPVGKIVLDRNPTNYFTEVEQLA 331
            |:..|:|.|.|:||||..|:|:|..|||||||||||..|:||:.|||:||:||..|||.||||.|
Worm   280 IESRNFPEWKMFIQVMTFEQAEKWEFNPFDVTKVWPHGDYPLIEVGKMVLNRNVKNYFAEVEQAA 344

  Fly   332 FSPAHMVPGIEPSPDKMLQGRLFAYGDSQRHRLGVNYMQIPVNCPYRVNVRNFQRDGAMTVTDNQ 396
            |.|||:|||||.|||||||||:|:|.|:..||||.||:|:|||||||......||||||.. ::|
Worm   345 FCPAHIVPGIEFSPDKMLQGRIFSYTDTHYHRLGPNYIQLPVNCPYRSRAHTTQRDGAMAY-ESQ 408

  Fly   397 NGAPNYFPNSFCG--PRESPRALGLQTCCPLSGDVYRFMSGDTEDNFSQVTDFWTYTLDNCGRKR 459
            ..|||||||||.|  .|:..:....||    :|||.|:.:|| :.|:.|...||...|....|.|
Worm   409 GDAPNYFPNSFRGYRTRDDVKESTFQT----TGDVDRYETGD-DHNYEQPRQFWEKVLKEEERDR 468

  Fly   460 LVRNLSEHLTEASQFLQERAVKLFTMVHSDFGRLMTEAL 498
            ||.||:..|....:.:|...||.||.||.|||..:...|
Worm   469 LVGNLASDLGGCLEEIQNGMVKEFTKVHPDFGNALRHQL 507

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9314	NP_001260268.1	KatE	10..501	CDD:223824	263/491 (54%)
		Catalase	28..406	CDD:278622	221/377 (59%)
		Catalase-rel	438..498	CDD:284128	22/59 (37%)
ctl-3	NP_741058.1	KatE	38..507	CDD:223824	258/474 (54%)
ctl-3	NP_741058.1	catalase_clade_3	79..507	CDD:163712	237/433 (55%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160167836
Domainoid	1	1.000	601	1.000	Domainoid score	I95
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H55514
Inparanoid	1	1.050	665	1.000	Inparanoid score	I391
Isobase	1	0.950	-	0	Normalized mean entropy	S486
OMA	1	1.010	-	-		QHG62736
OrthoDB	1	1.010	-	-		D172396at33208
OrthoFinder	1	1.000	-	-		FOG0001359
OrthoInspector	1	1.000	-	-		mtm4808
orthoMCL	1	0.900	-	-		OOG6_100495
Panther	1	1.100	-	-	O	PTHR11465
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X851
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	16	15.820