DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG9314 and Cat

DIOPT Version :9

Sequence 1:	NP_001260268.1	Gene:	CG9314 / 34198	FlyBaseID:	FBgn0032061	Length:	506	Species:	Drosophila melanogaster
Sequence 2:	NP_033934.2	Gene:	Cat / 12359	MGIID:	88271	Length:	527	Species:	Mus musculus

Alignment Length:	504	Identity:	294/504 - (58%)
Similarity:	369/504 - (73%)	Gaps:	4/504 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 SRDTASNQLIDYKNNDSEVQREI-TTSSGTPVGVKDAIQTVGPRGPALLQDFQFLDEVMHFDSER 66
            |||.||:|:..:|...:..:.:: ||..|.|:|.|..|.|.|.|||.|:||..|.||:.|||.||
Mouse     4 SRDPASDQMKQWKEQRASQRPDVLTTGGGNPIGDKLNIMTAGSRGPLLVQDVVFTDEMAHFDRER 68

  Fly    67 IPERVAYAKGAGAFGYFECTHDISKFCAASIFDKVRKRTAVAMRFSVACGEQGSADTVREQRGFA 131
            |||||.:|||||||||||.||||:::..|.:|:.:.|||.:|:|||...||.|||||||:.||||
Mouse    69 IPERVVHAKGAGAFGYFEVTHDITRYSKAKVFEHIGKRTPIAVRFSTVTGESGSADTVRDPRGFA 133

  Fly   132 VKFYTDDGIWDIVGCNMPVHYVRDPMLFPSLVHAQKRNPQTHLKDPDMFWDFMTLRPETLHALLM 196
            |||||:||.||:||.|.|:.::||.:||||.:|:||||||||||||||.|||.:||||:||.:..
Mouse   134 VKFYTEDGNWDLVGNNTPIFFIRDAILFPSFIHSQKRNPQTHLKDPDMVWDFWSLRPESLHQVSF 198

  Fly   197 YFSDRGTPDGYRHLHGYGVHTYRMINASGETQYVRFHFKTDQGIKNLDARRCEELMSHDPDYAIR 261
            .|||||.|||:||::|||.||::::||.||..|.:||:|||||||||.......|...||||.:|
Mouse   199 LFSDRGIPDGHRHMNGYGSHTFKLVNADGEAVYCKFHYKTDQGIKNLPVGEAGRLAQEDPDYGLR 263

  Fly   262 DLYNSIKKGNYPSWSMYIQVMLNEEAKKCRFNPFDVTKVWPQKDFPLLPVGKIVLDRNPTNYFTE 326
            ||:|:|..||||||:.|||||..:||:...|||||:|||||.||:||:||||:||::||.|||.|
Mouse   264 DLFNAIANGNYPSWTFYIQVMTFKEAETFPFNPFDLTKVWPHKDYPLIPVGKLVLNKNPVNYFAE 328

  Fly   327 VEQLAFSPAHMVPGIEPSPDKMLQGRLFAYGDSQRHRLGVNYMQIPVNCPYRVNVRNFQRDGAMT 391
            |||:||.|::|.||||||||||||||||||.|:.|||||.||:|||||||||..|.|:||||.|.
Mouse   329 VEQMAFDPSNMPPGIEPSPDKMLQGRLFAYPDTHRHRLGPNYLQIPVNCPYRARVANYQRDGPMC 393

  Fly   392 VTDNQNGAPNYFPNSFCGPRESPRALGLQTCCPLSGDVYRFMSGDTEDNFSQVTDFWTYTLDNCG 456
            :.|||.|||||:||||..|.:...||.....|.:  ||.||.|.: |||.:||..|:|..|:...
Mouse   394 MHDNQGGAPNYYPNSFSAPEQQRSALEHSVQCAV--DVKRFNSAN-EDNVTQVRTFYTKVLNEEE 455

  Fly   457 RKRLVRNLSEHLTEASQFLQERAVKLFTMVHSDFGRLMTEALNTARISK 505
            ||||..|::.||.:|..|:|::|||.||.||.|:|..:...|:.....|
Mouse   456 RKRLCENIAGHLKDAQLFIQKKAVKNFTDVHPDYGARIQALLDKYNAEK 504

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9314	NP_001260268.1	KatE	10..501	CDD:223824	288/491 (59%)
		Catalase	28..406	CDD:278622	244/377 (65%)
		Catalase-rel	438..498	CDD:284128	27/59 (46%)
Cat	NP_033934.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..34		10/29 (34%)
		KatE	17..500	CDD:223824	286/485 (59%)
		catalase_clade_3	68..497	CDD:163712	263/431 (61%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167850752
Domainoid	1	1.000	65	1.000	Domainoid score	I10023
eggNOG	1	0.900	-	-		E1_COG0753
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H55514
Inparanoid	1	1.050	693	1.000	Inparanoid score	I683
Isobase	1	0.950	-	0	Normalized mean entropy	S486
OMA	1	1.010	-	-		QHG62736
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0001359
OrthoInspector	1	1.000	-	-		otm42437
orthoMCL	1	0.900	-	-		OOG6_100495
Panther	1	1.100	-	-	O	PTHR11465
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X851
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	15	14.710