Protein Alignment CG9289 and NLGN4X

DIOPT Version :10

• Sequence 1: NP_609245.1
• Gene: CG9289 / 34195
• FlyBaseID: FBgn0032058
• Length: 674
• Species: Drosophila melanogaster
• Sequence 2: XP_005274621.1
• Gene: NLGN4X / 57502
• HGNCID: 14287
• Length: 836
• Species: Homo sapiens
• Alignment Length: 637
• Identity: 167/637 - (26%)
• Similarity: 264/637 - (41%)
• Gaps: 155/637 - (24%)

  Fly    71 QEPKVFTTTVPDLGRLRG-RT-LTTDWTGQKIMQFLDIPYGK----AERFRPAEPAPSWKGVLPA 129
            |.|.|.|    :.|::|| || |..:..| .:.|:|.:||..    ..||:|.||..||.|:...
Human    44 QYPVVNT----NYGKIRGLRTPLPNEILG-PVEQYLGVPYASPPTGERRFQPPEPPSSWTGIRNT 103

  Fly   130 HRPHAGCPS-------IQDLIVF---AKLE------EDGFDVEDCLRLSV--------NTKAM-- 168
            .:..|.||.       :.|::..   |.|:      :|  ..||||.|::        |||..
Human   104 TQFAAVCPQHLDERSLLHDMLPIWFTANLDTLMTYVQD--QNEDCLYLNIYVPTEDGANTKKNAD 166

  Fly   169 ---------------EGKSLPVMVYIHGDFFYDG------DSVEAAPGYLLEHDVVLVSVRYRLG 212
                           :....||||||||..:.:|      .|:.|:.|     :|:::::.||||
Human   167 DITSNDRGEDEDIHDQNSKKPVMVYIHGGSYMEGTGNMIDGSILASYG-----NVIVITINYRLG 226

  Fly   213 PFGFLSTLTDEMPGNAAVTDIILALKWVQQHIASFGGDPQRVTLFGQVGGAALVNVLTLSPAVPA 277
            ..|||||......||..:.|.|.||:|:::::.:|||||:|||:||...||:.|::|||| ....
Human   227 ILGFLSTGDQAAKGNYGLLDQIQALRWIEENVGAFGGDPKRVTIFGSGAGASCVSLLTLS-HYSE 290

  Fly   278 GLFHRVIYQSGTALSPAFITDAPLGATKAIGRIAGCKQSTKVDQLNKCLNRLNATMLLAAFSVHG 342
            |||.:.|.|||||||...:...|...|:.:....||......|.: :||...|...|:
Human   291 GLFQKAIIQSGTALSSWAVNYQPAKYTRILADKVGCNMLDTTDMV-ECLRNKNYKELI------- 347

  Fly   343 ENQPSLSGGAYGGVQLVIGGP---SGILPEHPGRLLAAEKFQAYPTMGGSVKHGGTFMLRDIFAD 404
              |.:::...|.    :..||   ..::|:.|..|:...:|..|..|.| |..|
Human   348 --QQTITPATYH----IAFGPVIDGDVIPDDPQILMEQGEFLNYDIMLG-VNQG----------- 394

  Fly   405 IFNETILDDTMTGRQYIDTIIEQANGADPSG---SWKEFSD----------------EEIFTQ-N 449
                       .|.:::|.|::..:|..|:.   |...|.|                :.::|. .
Human   395 -----------EGLKFVDGIVDNEDGVTPNDFDFSVSNFVDNLYGYPEGKDTLRETIKFMYTDWA 448

  Fly   450 DVKNGTFKRLTPGLIDLCSTISLKNPVLLVLQANAKKLPNSTYLYSFDYEGEQNRYATGEDEA-- 512
            |.:|...:|.|  |:.|.:......|.:.....:| :..:.||.|:|.:..:.....:..|.|
Human   449 DKENPETRRKT--LVALFTDHQWVAPAVATADLHA-QYGSPTYFYAFYHHCQSEMKPSWADSAHG 510

  Fly   513 NFVPFDMGVSLTDDNLYLFPWPRFLALNSNRDLKVARRMVALWTSFATTGVPQAPGLP------- 570
            :.||:..|:.:      :.|...|....|..|:.::..::..||:||.||.|..| :|
Human   511 DEVPYVFGIPM------IGPTELFSCNFSKNDVMLSAVVMTYWTNFAKTGDPNQP-VPQDTKFIH 568

  Fly   571 ---------AWPAMNDETGPYMKIDRTVSFGDNY-LDEYRIAVEEAKHGYNL 612
                     ||...|.:...|:.|.......|:| ..:....:|...|.:||
Human   569 TKPNRFEEVAWSKYNPKDQLYLHIGLKPRVRDHYRATKVAFWLELVPHLHNL 620

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG9289	NP_609245.1	COesterase	71..598	CDD:395084	163/621 (26%)
NLGN4X	XP_005274621.1	COesterase	44..610	CDD:395084	163/625 (26%)