Protein Alignment CG9289 and nlgn3a

DIOPT Version :10

• Sequence 1: NP_609245.1
• Gene: CG9289 / 34195
• FlyBaseID: FBgn0032058
• Length: 674
• Species: Drosophila melanogaster
• Sequence 2: XP_005157256.1
• Gene: nlgn3a / 562702
• ZFINID: ZDB-GENE-071219-1
• Length: 878
• Species: Danio rerio
• Alignment Length: 711
• Identity: 185/711 - (26%)
• Similarity: 292/711 - (41%)
• Gaps: 182/711 - (25%)

  Fly    66 QGQNGQEPKVFTTTVPDLGRLRGR--TLTTDWTGQKIMQFLDIPYGK----AERFRPAEPAPSWK 124
            :|| |..|.|.|    ..|:|||.  .|.::..| .:.|:|.:||..    .:||.|.||..||.
Zfish    63 RGQ-GYYPTVNT----QYGKLRGARVPLHSEILG-PVDQYLGVPYATPPVGEKRFLPPEPPSSWS 121

  Fly   125 GVLPAHRPHAGCP-----SIQDL-----------IVFAKLEEDGFDVEDCLRLSV---------- 163
            |:..|......||     ::.::           ||...:::..   ||||.|::
Zfish   122 GIKNATHFAPVCPQNIHNAVPEIMMPIWFTFNLDIVATSIQDQN---EDCLYLNIYVPTEDVKRI 183

  Fly   164 --------NTK---------AMEGKSL-----------------PVMVYIHGDFFYDG------D 188
                    |.|         ..:|:.|                 ||||||||..:.:|      .
Zfish   184 SKECTRKPNKKICRKGGTHSKKQGEDLSDNDGDEDEDIRDTGAKPVMVYIHGGSYMEGTGNMIDG 248

  Fly   189 SVEAAPGYLLEHDVVLVSVRYRLGPFGFLSTLTDEMPGNAAVTDIILALKWVQQHIASFGGDPQR 253
            ||.|:.|     :|:::::.:|:|..|||||......||..:.|.|.||:|:.::|..||||..|
Zfish   249 SVLASYG-----NVIVITLNFRVGVLGFLSTGDQAAKGNYGLLDQIQALRWISENIGYFGGDSNR 308

  Fly   254 VTLFGQVGGAALVNVLTLSPAVPAGLFHRVIYQSGTALSPAFITDAPLGATKAIGRIAGCKQSTK 318
            :|:||...||:.|::||||.. ..|||||.|.|||:|||...:...|:..|:.:....||.....
Zfish   309 ITVFGSGIGASCVSLLTLSHH-SEGLFHRAIIQSGSALSSWAVNYQPVKYTRLLAEKVGCNVLDT 372

  Fly   319 VDQLNKCLNRLNATMLLAAFSVHGENQPSLSGGAYGGVQLVIGGPSGILPEHPGRLLAAEKFQAY 383
            :|.:: ||.:.:|..|     |..:.||:....|:|.   ||.|  .::|:.|..|:...:|..|
Zfish   373 LDMVD-CLRKKSAREL-----VEQDIQPARYHVAFGP---VIDG--DVIPDDPEILMEQGEFLNY 426

  Fly   384 PTMGGSVKHGGTFMLRDIFADIFNETILD--DTMTGR-------QYIDTIIEQANGADPSGSWKE 439
            ..|.|..:..|   ||      |.|.::|  |.::|.       .::|::.....|.|......:
Zfish   427 DIMLGVNQGEG---LR------FVENVVDSEDGVSGNDFDFSVSDFVDSLYGYPEGKDTLRETIK 482

  Fly   440 FSDEEIFTQ-NDVKNGTFKRLTPGLIDLCSTISLKNPVLLVLQANAKKLPNSTYLYSFDYEGEQN 503
            |    ::|. .|..|...:|.|  |:.|.:......|.::....:| :..:.||.|:|.:..:..
Zfish   483 F----MYTDWADRDNPETRRKT--LVALFTDHQWVEPSVVTADLHA-RYGSPTYFYAFYHHCQSL 540

  Fly   504 RYATGEDEA--NFVPFDMGVSL---TDDNLYLFPWPRFLALNSNRDLKVARRMVALWTSFATTGV 563
            ......|.|  :.||:..|:.:   ||    |||. .|    |..|:.::..::..||:||.||.
Zfish   541 MKPAWSDAAHGDEVPYVFGIPMIGPTD----LFPC-NF----SKNDIMLSAVVMTYWTNFAKTGD 596

  Fly   564 PQAPGLP----------------AWPAMNDETGPYMKIDRTVSFGDNYLDEYRIAVEEA------ 606
            |..| :|                ||...|.:...|:.|    .......|.|| |.:.|
Zfish   597 PNKP-VPQDTKFIHTKANRFEEVAWSKYNPQDQLYLHI----GLKPRVRDHYR-ATKVAFWKHLV 655

  Fly   607 KHGYNLVNDEYYDLQEALLAASKLDSLNDANEEDEEDQDDAEGQRAASQTGGQNWVFIARK 667
            .|.|||     :|:.......:|:..|           :..:...:..:..|:.|.|..::
Zfish   656 PHLYNL-----HDMFHYTSTTTKVPPL-----------ETTQNSLSTKRPNGKAWPFNTKR 700

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG9289	NP_609245.1	COesterase	71..598	CDD:395084	167/629 (27%)
nlgn3a	XP_005157256.1	COesterase	69..651	CDD:395084	172/637 (27%)