Protein Alignment CG9289 and cest-9.2

DIOPT Version :10

• Sequence 1: NP_609245.1
• Gene: CG9289 / 34195
• FlyBaseID: FBgn0032058
• Length: 674
• Species: Drosophila melanogaster
• Sequence 2: NP_741910.3
• Gene: cest-9.2 / 259729
• WormBaseID: WBGene00007695
• Length: 617
• Species: Caenorhabditis elegans
• Alignment Length: 591
• Identity: 140/591 - (23%)
• Similarity: 218/591 - (36%)
• Gaps: 173/591 - (29%)

  Fly    71 QEPKVFTTTVPDLGRLRGRTLTTDWTGQKIMQFLDIPYGKAE----RFRPAEPAPSWKGVLPAHR 131
            |..||..|:   .||:||.|..:|....|.| |..:|:.|..    ||.|.:...||.|||.|.:
 Worm    19 QSLKVIETS---YGRVRGITEWSDDNNHKYM-FKSVPFAKPPIGKLRFAPPQYPDSWSGVLDASK 79

  Fly   132 PHAGCPSIQDLIVFAKLEEDGFDVEDCLRLSVNT--KAMEGKSLPVMVYIHGDFFYDGDSVEAAP 194
            ....|.|........:....    ||||.:::.|  |.:..| ..|:||.||. .|:|||....|
 Worm    80 YSPACLSNSSTTSTPQEHVS----EDCLYINIFTSEKCLRSK-CAVIVYFHGG-AYNGDSATMFP 138

  Fly   195 -GYLLE----HDVVLVSVRYRLGPFGFL----STLTDEMPGNAAVTDIILALKWVQQHIASFGGD 250
             .::||    .||:|.....|||.||.|    |.|..|   |..:.|.:.||.:|...|.:||||
 Worm   139 DNFILERYVAEDVILAIPGVRLGVFGQLYFGPSALLTE---NLFMFDAVQALDFVHNEIPNFGGD 200

  Fly   251 PQRVTLFGQVGGAALVNVLTLSPAVPAG--LFHRVIYQSGTALSPAFITDAPLGATKAIGRIAGC 313
            |::||:.|...|..||..|..|.:|...  ||.::|..|||.:...:  |..:..:..|....||
 Worm   201 PKQVTIMGHSSGGTLVEALGFSNSVDPDLKLFQQIIVLSGTGMFGFY--DLLVDNSFIISEKLGC 263

  Fly   314 KQSTK-------VDQLNKCLNRLNATMLLAAFSVHGENQPSLSGGAYGGVQLVIGGPSGILPEHP 371
            ...|:       :.::.:|:.:::                        |.::|
 Worm   264 FNGTQEERTDANIAEILECMRQID------------------------GHEIV------------ 292

  Fly   372 GRLLAAEKFQAYPTMGGSVKHGGTFMLRDIFADIFNETILDDTMTGRQYID---TIIEQANGADP 433
                            |..||     :.|::...|.     ..:.|..:::   .|.:..|...|
 Worm   293 ----------------GMQKH-----MEDVYKLTFK-----SLLRGAPFMELNGKIEKFRNSTSP 331

  Fly   434 SGSWKEFSDEEIFTQNDVKNGTFKRLTPGLIDLCSTISLKNPVLLVLQANAKKLPNSTYLYSFDY 498
            ..:  .|...|...:|:|:.  :..:|...:|      .:|||.:.              ..||.
 Worm   332 RNA--IFGTTEYEFRNEVER--YLYITTTFLD------FENPVAVA--------------QHFDD 372

  Fly   499 EGEQN--RYATGEDEANFV---PFDMGVSLTDDNLYLF---PWP---------RFLALN----SN 542
            |..||  ....|:..:.||   .|...::....::|||   .||         .|:.::    ..
 Worm   373 ELMQNMDTMINGDAVSIFVSAAAFSSAMANAGADVYLFETRQWPYSFHVSDMQYFIGIHREVLHT 437

  Fly   543 RDLKVARRMVA-LWTSFATTGVPQAPGLPAWPAMNDETGPYMKI-----------------DRTV 589
            .|:.:.....: |..:|..||.|.    |.|.::..|...|:::                 |:.|
 Worm   438 HDMDILDSFYSKLLVNFTKTGAPS----PEWNSLEPEKMNYLELRVDTRNGKGPVMLEGYHDKEV 498

  Fly   590 SF--GD 593
            ||  ||
 Worm   499 SFWYGD 504

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG9289	NP_609245.1	COesterase	71..598	CDD:395084	140/591 (24%)
cest-9.2	NP_741910.3	alpha/beta hydrolases	22..501	CDD:473884	136/583 (23%)