Protein Alignment CG9289 and cest-3

DIOPT Version :10

• Sequence 1: NP_609245.1
• Gene: CG9289 / 34195
• FlyBaseID: FBgn0032058
• Length: 674
• Species: Drosophila melanogaster
• Sequence 2: NP_510042.2
• Gene: cest-3 / 181385
• WormBaseID: WBGene00008451
• Length: 588
• Species: Caenorhabditis elegans
• Alignment Length: 557
• Identity: 122/557 - (21%)
• Similarity: 211/557 - (37%)
• Gaps: 133/557 - (23%)

  Fly    69 NGQEPKVFTTTVPDLGRLRGRTLTTDWTGQKIMQFLDIPYGKAERFRPAEPAPSWKGVLPAHRPH 133
            ||...::.:||   .|:|.|:|:..|....|.:.|...|.||. ||...|....||.:..|....
 Worm    17 NGSGQRIISTT---YGKLEGKTVNVDQHMFKNVPFAKPPLGKL-RFSLPEWTNPWKNIRNATEYS 77

  Fly   134 AGCPSIQDLIVFAKLEEDGFDV-EDCLRLSV--NTKAMEGKSLPVMVYIHGDFFYDGDSVEAAPG 195
            ..|.|...:    :.:.:.|.: ||||.|:|  |...::.|:...:||.||.......:|:....
 Worm    78 PSCFSNSSM----RTDSNFFPMSEDCLYLNVFTNEYCLKSKNCSTVVYYHGGGINMDSAVQFNDT 138

  Fly   196 YLLE----HDVVLVSVRYRLGPFGFLSTLTDEM-PGNAAVTDIILALKWVQQHIASFGGDPQRVT 255
            ::||    .:||.:...||||.||.|...::.: |.|.|:.|..|||:::.|.|::|||....:.
 Worm   139 FILERYVKENVVFIIPAYRLGIFGLLYFGSNNLVPQNLAIHDCELALRFIHQEISNFGGHKDDIN 203

  Fly   256 LFGQVGGAALVNVLTLSPAVPAG--LFHRVIYQSGTALSPAFITDAPLGATKAIGRIA---GCKQ 315
            |.|...||.:..:...|..:...  |.:|:|     .|||....|.|....|.....|   ||.:
 Worm   204 LMGHSAGAHISLIFGFSRHIDPDHKLINRII-----VLSPVPSYDMPELLIKNCYDFAERVGCYK 263

  Fly   316 ---STKVDQLNKCLNRLNATMLLAAFSVHGENQPSLSGGAYGGVQLVIGGPSGILPEHPGRLLAA 377
               :.:..::.|||.:.:|..|::.                                  .||:..
 Worm   264 RNVTARDTEIVKCLRKKDARGLMSM----------------------------------QRLMEN 294

  Fly   378 EKFQAYPTMGGSVKHGGTFMLRD-IFADIFNETILDDTMTGRQYIDTI----IEQANGADPSGSW 437
            ::...:..:.|.     .||.|| ..||.....:..|.:.|.. :|.:    :::.|.| .:||:
 Worm   295 DRLYFWNFLAGE-----PFMYRDESIADFKEYAVKRDMLIGNT-VDEVKWKRLKKENPA-IAGSF 352

  Fly   438 KEFSDE-------EIFTQNDVKNGTFKRLTPGLIDLCSTISLKNPVLLVLQANAKKLPNSTYLYS 495
            .::.:.       ..:..:...|.|::..|.|:....:|.:       ..||||   ..:.||:.
 Worm   353 MDWENPYEVAHKFNFYHDSAPVNSTYESFTQGIFVSTATYA-------EAQANA---GGTVYLFQ 407

  Fly   496 FDYEGEQN----RYATGEDEANFVPFDMGVSLTDDNLYLFPWPRFLALNSNRDLKVARRMVALWT 556
            .:.:...:    :|..|....::...||.:.   |..|                   .:|:..:|
 Worm   408 SNQQPSSHVSDMQYFVGTHREDYHTSDMDIM---DTFY-------------------SKMIVNFT 450

  Fly   557 SFATTGVPQAPGLPA---------------WPAMNDE 578
            .|.:......|.:|:               ||.|.::
 Worm   451 KFGSPSPVWEPLVPSRMNYYALEVNTEKGIWPRMEED 487

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG9289	NP_609245.1	COesterase	71..598	CDD:395084	120/555 (22%)
cest-3	NP_510042.2	alpha/beta hydrolases	21..496	CDD:473884	120/553 (22%)