Protein Alignment CG9289 and cest-2.2

DIOPT Version :10

• Sequence 1: NP_609245.1
• Gene: CG9289 / 34195
• FlyBaseID: FBgn0032058
• Length: 674
• Species: Drosophila melanogaster
• Sequence 2: NP_001256567.1
• Gene: cest-2.2 / 179917
• WormBaseID: WBGene00013874
• Length: 672
• Species: Caenorhabditis elegans
• Alignment Length: 703
• Identity: 165/703 - (23%)
• Similarity: 245/703 - (34%)
• Gaps: 211/703 - (30%)

  Fly    68 QNGQEPKVFTTTVPDLGRLRGRTLTTDWT---GQKIMQFLDIPYGKAE----RFRPAEPAPSWKG 125
            ||.:..||..::  ..|.:.|||||..::   .|..:.|..:||.:..    |||...|...|.|
 Worm    13 QNVRSTKVKLSS--RTGTIEGRTLTASYSPLGNQTGIVFFGVPYVEPPVGNLRFRKPRPPKPWDG 75

  Fly   126 VLPAHRPHAGCPSIQDLIVFAKLEEDGFD---VEDCLRLSV--NTKAMEGKSLPVMVYIHGDFFY 185
            ||.|....|.|.|.|     .|..::|..   .||||..:|  |...:|.|:..||:.|||..|.
 Worm    76 VLEAKEYKAACMSDQ-----KKTYKNGVGGPVSEDCLYANVFTNQYCLEHKNCSVMLTIHGGRFV 135

  Fly   186 DGDSVEAAPGYLLE----------HDVVLVSVRYRLGPFGFLSTLTDEMPGNAAVTDIILALKWV 240
                :|:|..|..|          .::|:|:..||||.||......|....|..:.||:..::|.
 Worm   136 ----IESASAYDPEIIINNFVGQGRNIVVVTFNYRLGLFGLGMLNGDNQDTNFGLYDILEVVRWT 196

  Fly   241 QQHIASFGGDPQRVTLFGQVGGAALVNVLTLSPAVPAGLFHRVIYQSGTALSPAFITDAPLGATK 305
            ::.|.:||||..|:|:.|...||......:.|| :..||.|:.|..|.:..:  ....:.:....
 Worm   197 RKEIKNFGGDKDRITMQGHSAGAVFTAAFSTSP-LSKGLIHQQIIMSASMSN--LSKKSNVKELT 258

  Fly   306 AIGRIAGC---------KQSTKVDQLNKCLNRLNATMLLAAFSVHGENQPSLSG-GAYGGVQLVI 360
            .:.||.||         ..:.:|::...||...:|..:|.|......|.....| |...|:..|
 Worm   259 VVARIVGCLPDEHGFPKLSNVEVEKAYTCLRSKSAQQILDAQLYMLRNTTYYIGQGHIDGIYQV- 322

  Fly   361 GGPSGILPEHPGRLLAAEKFQAYPTMGGSVKHGGTFMLRDIFADIFNETILDDTMTGRQYI--DT 423
                    ::|..|.|........||.|:.    |..|.|      :..|:|...||::.|  ..
 Worm   323 --------DYPDNLYATNSIYPINTMIGTT----TAELMD------SRYIVDPKNTGKKEILLQN 369

  Fly   424 IIEQANGADPSGSWKEFSDEEIFTQ---NDVKNG-TFKRLTP------GLIDLCSTISLKNPVLL 478
            :.|..       .::.:.:.|.|:|   |..||| ..|.|..      |.|.|.:..|.|:
 Worm   370 LCEHI-------GYELYKEPEEFSQKCRNFYKNGEDAKSLGDDMEFYYGAIQLANVHSSKD---- 423

  Fly   479 VLQANAKKLPNSTYLYSFDYE-----------------GEQNRYATGEDEANFVPFDMGVSLTDD 526
                      .:.::|||||:                 ||...||.|.:..||
 Worm   424 ----------TNVFVYSFDYKEAGNAYKKYDKSLSPKHGEDFAYAFGTNRGNF------------ 466

  Fly   527 NLYLFPWPRFLALNSNRDLKVARRMVALWTSFATTGVPQAPGLPAWPAMNDETGPYMKIDRTVSF 591
                          |.:|..:......::..|...|.|.......|.....|...|..||...:|
 Worm   467 --------------STKDYVIEYIYSGMFADFVNFGDPSPLEDQEWAQYTPEKREYFLIDFDKNF 517

  Fly   592 -----GDNYLDEYRIAVE--------EAKHGY----------NLVN------------------- 614
                 .|:|   |..|:|        ..|..:          ||:|
 Worm   518 TMPGMKDHY---YPKALEFWSTCGSKSFKEHFSPSVDIFIIGNLLNPIMSHLNHNETGPDKTFEQ 579

  Fly   615 -DEYYDLQEALL----AASKLD--------------------SLNDANEEDEE 642
             |:.|:.:|..|    |..||:                    .|...|||::|
 Worm   580 FDKLYNEREEFLKLLKAVRKLEIQKKMWRGRSSKDLMLKELVDLEKINEEEQE 632

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG9289	NP_609245.1	COesterase	71..598	CDD:395084	144/592 (24%)
cest-2.2	NP_001256567.1	alpha/beta hydrolases	25..534	CDD:473884	145/589 (25%)