Protein Alignment CG9289 and cest-4

DIOPT Version :10

• Sequence 1: NP_609245.1
• Gene: CG9289 / 34195
• FlyBaseID: FBgn0032058
• Length: 674
• Species: Drosophila melanogaster
• Sequence 2: NP_501043.1
• Gene: cest-4 / 177445
• WormBaseID: WBGene00015930
• Length: 592
• Species: Caenorhabditis elegans
• Alignment Length: 559
• Identity: 137/559 - (24%)
• Similarity: 215/559 - (38%)
• Gaps: 142/559 - (25%)

  Fly   107 PYGKAERFRPAEPAPSWKGVLPAHRPHAGCPSIQDLIVFAKLEEDGFDVEDCLRLSVNT--KAME 169
            |.||. ||:..||...|.||..|......|.|...:....:...|    ||||.:::.|  |.::
 Worm    56 PIGKL-RFQKPEPPEKWTGVRNAKAYGPACISNSSVSTSPQKWID----EDCLHINIFTSDKCLK 115

  Fly   170 GKSLPVMVYIH-GDFFYDGDSVEAAPGYLL----EHDVVLVSVRYRLGPFGFLSTLTDE--MPGN 227
            .|...|:.|.| |...|| .:|.....|||    ..||::....:|||.|... .:.|:  .|.|
 Worm   116 SKDCAVVTYFHGGGLMYD-SAVMFNDTYLLGTFVNQDVIIAIPAFRLGIFSHF-VVEDQSIAPTN 178

  Fly   228 AAVTDIILALKWVQQHIASFGGDPQRVTLFGQVGGAALVNVLTLSPAVPAGLFHRVIYQSGTALS 292
            .|:.||:|.:::|:..|.:|||:.|:.|:.|...|.::||:||.|..:...|   .::|....:|
 Worm   179 LALYDILLGVEFVKNEIHNFGGNNQKNTIMGHSYGGSIVNILTFSSKINHDL---SLFQQSICMS 240

  Fly   293 PA--FIT-DAPLGATKAIGRIAGC--------KQSTKVDQL--NKCLNRLNATMLLAAFSVHGEN 344
            ..  |.| :..:..|....:.|||        |.:|:...|  .|||...:|..||.
 Worm   241 SGHDFETLEIQIQKTNRFAKHAGCTVPSIIEKKMTTRQSDLYRMKCLQNKDALELLR-------- 297

  Fly   345 QPSLSGGAYGGVQLVIGGPSGILPEHPGRLLAAEKFQAYPTMGGSVKHGGTFMLRDI-FADIFNE 408
                       ||               |||..|   .|||.|..|:...  ::::| :.:....
 Worm   298 -----------VQ---------------RLLEDE---GYPTYGYLVQREP--LIQEIPYQEFMKS 331

  Fly   409 TILDDTMTG--RQYID-----TIIEQANG-ADPSGSWKEFS---DEEIFTQNDVKNGTFKRLTPG 462
            ......:||  |..:|     ..|.||.| .:|...:.:|.   |:|::     :.|.....|..
 Worm   332 PKKIPMLTGCTRYEMDHSPAPKPIGQALGFENPEEVYMKFRKDWDDEVY-----EFGNHSDETQA 391

  Fly   463 LIDLCSTISLKNPVLLVLQAN---AKKLPNSTYLYSFDYEGEQNRYATGEDEANFVPFDMGVSLT 524
            ::           |.:.::.|   :|.:|  .|||.:.|......                   |
 Worm   392 IM-----------VQVRVRVNNLLSKNVP--AYLYEYTYPKHARH-------------------T 424

  Fly   525 DDNLYLFPWPRFLALNSNRDLKVARRMVALWTSFATTGVPQAPGLPAWPAMND---------ETG 580
            ||..||....||  .....::::.:....::.:||..|.|: .|.....|.|:         |||
 Worm   425 DDLFYLMGVHRF--EKDENEIELGKVYETIFMNFAKFGDPK-EGFELANAENESYYEVYWDGETG 486

  Fly   581 --PYMKIDRTVSFGDNYLDEY-RIAVEEAKHGYNLVNDE 616
              |.||    ..|.:..::.: :..||..||...|.|.:
 Worm   487 ERPQMK----TKFEEKIINYWLKDMVEYDKHITELKNQK 521

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG9289	NP_609245.1	COesterase	71..598	CDD:395084	131/538 (24%)
cest-4	NP_501043.1	alpha/beta hydrolases	26..503	CDD:473884	131/539 (24%)